Molecular Diagnostics
Multicancer Blood Test Aids Screen for Cancer Guide Intervention
As minimally invasive screening tests, liquid biopsies could help reduce cancer-specific morbidity and mortality through earlier detection. However, there is debate on how to effectively screen large populations for cancer, including individuals who do not have symptoms or history of the disease. More...12 May 2020
CRISPR-Based Microarray System Enables Massive Testing for Viral Pathogens
A novel microfluidic nucleic acid-based diagnostic system is capable of detecting a specific virus from a catalog of more than 160 human pathogens, including the COVID-19 coronavirus, simultaneously in more than 1,000 samples. More...11 May 2020
![Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2020-05-07/GMS-062B.jpg "Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention)")
A Series of Sensitive and Specific DNA-Based Assays Detects and Differentiates Salmonella Serotypes
A team of Australian researchers developed a series of sensitive and specific assays to detect and identify different serotypes (serovars) of Salmonella, a common cause of bacterial foodborne disease worldwide. More...07 May 2020
Targeted Next-Generation Sequencing Validated for Lysosomal Storage Disorders Diagnosis
Lysosomal storage disorders (LSDs) are a group of more than 50 inherited rare disorders characterized by the accumulation of specific undegraded metabolites in the lysosomes. This overstorage is commonly caused by a deficient or absent activity of one of the many lysosomal hydrolases or, in a few cases, by the deficit of other non-enzymatic lysosomal proteins. More...04 May 2020
Phosphorylated Tau Protein Blood Test Distinguishes Alzheimer’s Disease from Other Neurological Disorders
A recently developed blood test has confirmed the hypothesis that elevated levels of circulating phosphorylated tau 181 (pTau181) protein correlate with Alzheimer's disease (AD) and distinguish it from other neurological disorders that may be misdiagnosed as AD. More...04 May 2020
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In Other News
Proteomic Analysis of Urinary Extracellular Vesicles for the Diagnosis of Prostate Cancer
Liquid Biopsy Assay for the Early Detection of Pancreatic Cancer
Scabies Detected by Molecular Methods in Skin Scrapings
Genetic Alterations Analyzed in Pediatric Low-Grade Glioma
Molecular Differences Discovered Among Ovarian Cancer Subgroups
Human NK Cells Identified by Single-Cell RNA Sequencing
Important Genetic Mechanism Behind Inflammatory Bowel Disease Revealed
Acetylated Tubulin Is a Biomarker for Severe Depression
Missing BAP1 Gene Associated with Immunosuppressive Molecules in Uveal Melanoma
Large Proteomics Study Identifies New Fluid Biomarkers for Diagnosis of Alzheimer’s Disease
A Non-Invasive Urine Test for Prediction of Kidney Transplant Failure
Real-Time Assay Evaluated for Two Sexually Transmitted Diseases
RT-LAMP Assay Developed for SARS-CoV-2
Genetic Risk Score Predicts Prostate Cancer Drug Response
Novel Inherited Mutation Predisposes Children to Medulloblastoma
SARS-CoV-2 Found in Sputum/Feces After Negative Pharyngeal Specimens
Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Protein Biomarker Is Early Predictor of Likelihood of Developing Liver Disease
Liquid Biopsy Lung Cancer Screening Method Developed
Circulating RNA Biomarker Predicts Likelihood of Developing Alzheimer’s Disease
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Early Tumor Detection by Analysis of Circulating Free DNA Methylation Patterns
Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.