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Clinical Chemistry

Image: A liquid chromatography-tandem mass spectrometer (LC-MS/MS) (Photo courtesy of University of Michigan).

Low Total Testosterone Linked to Chronic Disease

A male's total testosterone level may be linked to more than just sexual health and muscle mass preservation. Low amounts of the hormone could also be associated with chronic disease, even among men 40 years of age and younger. More...
01 May 2018
Image: The G5 mobile continuous glucose monitoring (CGM) system (Photo courtesy of Dexcom).

Continuous Glucose Monitor Benefits Diabetics

Continuous glucose monitors (CGM) offer significant, daily benefits to people with type 1 diabetes, providing near-real time measurements of blood sugar levels, but they can be expensive. More...
24 Apr 2018
Image: The N Latex Cystatin C Assay for the detection of decline in renal function (Photo courtesy of Siemens Healthcare).

BTP Viewed As Glomerular Filtration Rate Marker

Beta Trace Protein (BTP) is a promising marker of glomerular filtration rate (GFR) as it was reported to be increased in the serum of patients with renal disease. Some evidence suggests that it is more sensitive than creatinine (Cr) at detecting early changes in GFR. More...
24 Apr 2018
Image: The Synergy H1 Hybrid Multi-Mode Microplate Reader (Photo courtesy of BioTek).

Vitamin D Blood Test May Speed Pediatric Bipolar Diagnosis

Major mood disorders (MMD), specifically bipolar disorder (BD) and major depressive disorder (MDD), are some of the most prevalent albeit under-diagnosed health problems in children and adolescents. Worldwide among adolescents, MDD and BD are the first and fourth most disabling conditions, respectively. More...
18 Apr 2018
Image: Determination of the amyloid‐beta (Aβ) secondary structure distribution in blood plasma by an immuno‐IR‐sensor correlates with PET scanning and CSF markers in Alzheimer\'s disease (AD) patients, with potentials to be an accurate, simple, and minimally invasive biomarker for early AD detection (Photo courtesy of Ruhr University Bochum).

Amyloid Blood Biomarker Detects Alzheimer's Disease

There is, as yet, no cure for Alzheimer's disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention. Alzheimer's disease is thought to begin long before patients show typical symptoms like memory loss. More...
17 Apr 2018
Image: A diagram of two different forms of heart failure compared with a normal heart (Photo courtesy of The Medical University of South Carolina).

CV Biomarkers Associated with Incident Heart Failure

Nearly half of all patients with heart failure have preserved ejection fraction as opposed to reduced ejection fraction, yet associations of biomarkers with future heart failure subtype are incompletely understood. More...
12 Apr 2018
Image: The Dexcom 6 is an integrated continuous glucose monitoring (iCGM) system for determining blood glucose (Photo courtesy of DEXCOM).

Interoperable Glucose Monitoring System Authorized

An integrated continuous glucose monitoring (iCGM) system for determining blood glucose levels in children aged two years and older and adults with diabetes has been authorized. More...
10 Apr 2018
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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