Pathology

$Image: Determination of the amyloid‐beta (Aβ) secondary structure distribution in blood plasma by an immuno‐IR‐sensor correlates with PET scanning and CSF markers in Alzheimer\'s disease (AD) patients, with potentials to be an accurate, simple, and minimally invasive biomarker for early AD detection (Photo courtesy of Ruhr University Bochum).$

Amyloid Blood Biomarker Detects Alzheimer's Disease

There is, as yet, no cure for Alzheimer's disease. It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention. Alzheimer's disease is thought to begin long before patients show typical symptoms like memory loss. More...
17 Apr 2018

Confocal Fluorescence Microscopy Used for Rapid Tissue Evaluation

Optical imaging techniques are currently available for imaging tissues without the need for any type of extensive tissue preparation. There are several applications for their potential use in surgical pathology practice. More...
16 Apr 2018

Sampling Device Increases Detection of Barrett’s Esophagus

Esophageal adenocarcinoma, one of the most fatal and fastest growing cancers in the USA, can be prevented if detected at a precancerous stage. In Barrett’s esophagus (BE), esophageal squamous mucosa is replaced by metaplastic columnar mucosa predisposed to developing esophageal adenocarcinoma (EAC). More...
12 Apr 2018

Aggressive Meningioma Linked to Transcription Factor Activity

Meningioma, a cancer of the cerebral and spinal meninges, is the most common primary CNS tumor in the USA. Meningioma is the most common primary intracranial tumor, but the molecular drivers of aggressive meningioma are incompletely understood. More...
12 Apr 2018

Image: The Ion Personal Genome Machine (PGM) System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data (Photo courtesy of Thermo Fisher Scientific).

Gut Microbiome Analysis Predicts Hospitalizations in Cirrhosis

Cirrhosis is a leading cause of mortality and healthcare expenditure due to hospitalizations worldwide. Bacterial products such as endotoxin play a key role in the development of a proinflammatory milieu and disease progression in cirrhosis. More...
11 Apr 2018

Image: UW-OncoPlex is a diagnostic tool that uses genetic sequencing to look for mutations that cause cancer (Photo courtesy of University of Washington).

Genomic Test Detects Lynch Syndrome in Colorectal Cancer

Lynch syndrome (LS) affects approximately 3% of all patients with colorectal cancer (CRC), making it the most common hereditary syndrome that predisposes individuals to develop CRC. Universal tumor screening for LS in CRC is recommended and involves up to six sequential tests. More...
11 Apr 2018

Image: A senior medical laboratory scientist conducting the IsolateFibromyalgia blood test (Photo courtesy of IquityLabs).

Novel RNA Blood Test Launched for Fibromyalgia

It is estimated that about five million Americans suffer from fibromyalgia, a poorly understood disorder characterized by deep tissue pain, fatigue, headaches, mood swings and insomnia. It often takes years for a patient to be diagnosed with fibromyalgia and some doctors still refuse to recognize it as a disease. More...
10 Apr 2018

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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.