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Pathology

Image: The gut contains trillions of microorganisms, but new research finds one bacterium that drives the growth of colorectal cancer cells (Photo courtesy of MNT).

Bacterium Actively Drives CRC Tumor Growth

Colorectal cancer (CRC) is a leading cause of cancer-related death. The recognition that microbial agents can contribute to the development of CRC raises hope for improving CRC diagnosis and treatment by incorporating both microbial and patient characteristics into clinical strategies. More...
27 Jul 2017
Image: A diagram of microRNA-mediated dynamic bidirectional shift between the subclasses of glioblastoma stem-like cells (Photo courtesy of Brigham and Women\'s Hospital).

Specific MicroRNA Identifies Glioblastoma Subtypes

Glioblastoma multiforme (GBM), an extremely aggressive brain cancer, is a very complex disease. It is characterized by a fast-growing tumor in the brain composed of many subpopulations of cells, including glioblastoma stem cells, which play a crucial role in glioblastoma initiation, expansion and therapy-resistance. More...
26 Jul 2017
Image: The Afirma Gene Expression Classifier kit for thyroid FNA Analysis reduces thyroid cancer surgery treatment costs (Photo courtesy of Veracyte).

Molecular Testing Evaluated for Thyroid Nodules

Thyroid nodules are a common clinical concern and increasing use of diagnostic imaging likely explains a large part of the increased incidence of thyroid nodules and the subsequent diagnosis of thyroid cancer that has been observed during the last three decades. More...
26 Jul 2017
Image: The AbsoluteIDQ p180 kit identifies and quantifies more than 180 metabolites from five different compound classes (Photo courtesy of Biocrates Life Sciences).

Pre-Diagnostic Metabolite Concentrations Related to Cancer Risk

Prostate cancer is the second most commonly diagnosed cancer in men worldwide, but circulating insulin-like growth factor I is the only established risk factor that is potentially modifiable. More...
25 Jul 2017
Image: The device employs two systems in miniature: a flow system and an optical system. The ratio of the two systems provides a quantitative indication about how the cancer is progressing (Photo courtesy of the Universitat Rovira i Virgili).

Optofluidic Device Quantifies CTCs in Blood

Researchers have developed a portable device that rapidly detects and counts circulating tumor cells (CTCs) in blood samples. It can help provide early diagnosis and help assess a patient’s level of health with convenient, inexpensive, effective testing for monitoring patients with cancer. More...
25 Jul 2017

Parkinson’s Disease Patients at Higher Risk for Melanoma

Study finds that people with Parkinson’s disease have a much higher risk of the skin cancer melanoma, and vice versa. Physicians treating patients with one disease should be vigilant for signs of the other in order to achieve early diagnosis and treatment, and patients should be educated about the risk of developing the other illness. More...
24 Jul 2017
Image: A histopathology of a skin biopsy from a patient with amyloidosis. Protein clumps are in red (Photo courtesy of Professor Michael Polydefkis).

Nerve Biomarkers Found for Amyloid Polyneuropathy

A modified skin biopsy that hastens the earlier diagnosis of an inherited and progressively fatal nerve disease has been described that seems to offer a clearer view of the disorder's severity and progression. More...
19 Jul 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.