Pathology

Urinary Cell-Free DNA Detects Urothelial Carcinoma
Most bladder cancers start in the innermost lining of the bladder, which is called the urothelium or transitional epithelium. As the cancer grows into or through the other layers in the bladder wall, it has a higher stage, becomes more advanced, and can be harder to treat. More...08 Jan 2020

Cardiac Blood Test Predicts Post-Surgical Outcomes
Globally, of the 200 million adults who undergo major surgery, 18% will experience serious cardiac and vascular complications including death within 30 days following their intervention, such as hip and knee replacements, bowel resections and abdominal aortic aneurysm repair. More...08 Jan 2020

Extrachromosomal Circular DNA Drives Oncogenic Genome Remodeling in Neuroblastoma
Circularized DNA falling outside of linear chromosomes may serve as a recurrent source of somatic rearrangements in neuroblastoma, a pediatric cancer affecting immature cells in the sympathetic nervous system. More...02 Jan 2020
Liquid Biopsy Detects Breast Cancer Residual Disease
The concept of circulating DNA or tumor cells to identify patients with residual cancer present after early-stage, putatively curative treatment has made rapid strides across multiple tumor types since some of the first promising tests in colorectal cancer. More...02 Jan 2020
Standard Pathology Tests Outperform Molecular Subtyping in Bladder Cancer
Evolving diagnostic approaches include compiling databanks on gene expression and mutations present in a cancer type to find patterns of gene expression that are then used to subtype tumors that "pathologically look similar" but are molecularly different. More...02 Jan 2020

Stool DNA Test Helps Detect Precancerous Lesions
Colorectal cancer (CRC) is the third most common cancer and is one of the leading causes of cancer-related mortality. Although CRC incidence is increasing, a decrease in mortality has been observed due to the implementation of CRC screening and improved therapies. More...27 Dec 2019

In Other News
Childhood Kidney Cancer Arises from Altered Normal Tissue
Chronic Comorbidities Are Prevalent Among People with Chagas Disease
Pulmonary Embolism Diagnosed by Improved Interpretation of Blood Tests
Genetic Architectures of Schizophrenia Compared in Different Populations
Marker Panel Detects Early Liver Cancer with Increased Sensitivity
Rare Genetic Variants Associated with Sudden Cardiac Death
New Blood Test Marks Progress in Battle Against Sepsis
Longitudinal Molecular Trajectories of Adult Diffuse Glioma Examined
New Biomarker Discovered for Cancer Stem Cells
Mycobacterium Infection Found in Gastric Patients’ Stomachs
Novel, High-Accuracy Blood Test Can Screen for Multiple Cancers
Crohn's Disease-Associated Bacteria Tolerate Antibiotics
Second Malignancy Risk Higher for Some Leukemia Survivors
Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants
Innovative Blood Test Aids Early Detection of Breast Cancer
Aqueous Humor Is Superior to Blood to Diagnose Retinoblastoma
Automated Immunoassay Systems Evaluated for KL‐6 Antigen Quantification
High Levels Of Blood Hormones Raise Prostate Cancer Risk
Prostate Cancer Methylation Levels Linked to Epigenetic Profiles
Metastatic Tumor Profiles Lead to Potential Treatment Targets
Full Analytical Data Validated for Target Selector ctDNA Assays
Post-Treatment Colon Cancer Recurrence Identified by ctDNA Detection
Metabolic Classification of Thyroid Nodules Uses MS Imaging
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.







