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Pathology

Image: Since fluid from the Pap test occasionally contains cells from the endometrium or ovaries, scientists found they could detect cancer cells from these organs that are present in the fluid by using different brushes (Photo courtesy of Johns Hopkins University).

Cervical Fluid Test Developed for Gynecological Cancers

Together, endometrial and ovarian cancers account for about 25,000 deaths each year and are the third leading cause of cancer-related mortality in women in the USA. Most of these deaths are caused by high-grade tumor subtypes, which tend to metastasize before the onset of symptoms. More...
03 Apr 2018
Image: The HiSeq2000 instrument used for whole-genome sequencing targeted resequencing, gene expression level detection, DNA methylation profiling, de novo sequencing, metagenomic studies, and ChiP-seq (Photo courtesy of Illumina).

Chromosome Interaction Profiling Reveals Cancer Risk Genes

Breast cancer is a heterogeneous disease with two main subtypes defined by the presence (ER+) or absence (ER−) of the estrogen receptor. Approximately 80% of newly diagnosed breast cancers are ER+ although this proportion varies with age at diagnosis and ethnicity. More...
29 Mar 2018
Image: New cutting edge technology can be used to grade cancer tumors, eradicating human subjectivity. A traditional stained H+E biopsy (L) and a Digistain view (R) (Photo courtesy of Imperial College London).

Cutting Edge Technology Used to Grade Cancer Tumors

Biopsy specimens are processed into formalin-fixed-paraffin-embedded (FFPE) blocks and currently, hematoxylin and eosin (H + E) stained sections are widely used for the histopathological diagnosis of cancer and other pathologies. More...
28 Mar 2018
Image: The NextSeq 500 benchtop sequencer delivers on-demand exome, transcriptome and whole-genome sequencing (Photo courtesy of Illumina).

Distinct Epigenetic Features Found in Alzheimer's Brains

Aging is the strongest risk factor for Alzheimer’s disease (AD), although the underlying mechanisms remain unclear though AD tends to coincide with certain chromatin shifts in the aging brain. More...
21 Mar 2018
Image: Extracellular vesicles (red) released from a patient’s tumor and captured on the surfaces of the EVHB-Chip (Photo courtesy of Professor Shannon Stott, PhD).

Microfluidic Device Captures Tumor-Specific Extracellular Vesicles

A microfluidic device has been developed that can capture glioblastoma-derived extracellular vesicles, with high specificity, using very small blood samples, which would be useful for pediatric patients. More...
21 Mar 2018
Image: The CellDetect platform is the only histochemical solution providing color discrimination between normal, pre-cancer and cancer cells alongside morphological examination (Photo courtesy of Micromedic Technologies).

Non-Invasive Urine Test Detects Prostate Cancer

Prostate cancer is the second most common cancer among men worldwide. About one man in nine will be diagnosed with prostate cancer during his lifetime. It is estimated that in the USA for 2018 there will be about 165,000 new cases of prostate cancer and about 29,000 deaths from prostate cancer. More...
15 Mar 2018
Image: The QX200 AutoDG automated droplet generator, part of the Bio-Rad QX200 PCR System (Photo courtesy of Compass Design).

Blood Test Predicts Patient Response to Chemotherapy

Early changes in circulating tumor DNA (ctDNA) level may provide early response prediction, but the impact of tumor heterogeneity is unknown. More...
14 Mar 2018
New
Gold Member
C-Reactive Protein Reagent
CRP Ultra Wide Range Reagent Kit
Automated Blood Typing System
IH-500 NEXT
New
Gold Member
Syphilis Screening Test
VDRL Antigen MR
New
Thyroxine ELISA
T4 ELISA


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.