Pathology
Tumor DNA Platform Classifies Colorectal Cancer
Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. More...15 Jan 2020
Plasma HSP90α Levels Used for Detection of Hepatocellular Carcinoma
Liver cancer is composed mostly of primary liver cancers and secondary liver cancers. Hepatocellular carcinoma (HCC), as the major type of primary liver cancer, is the fifth most common tumor worldwide and the third leading cause of cancer mortality, responsible for 745,500 cancer deaths annually. More...14 Jan 2020
Urinary Cell-Free DNA Detects Urothelial Carcinoma
Most bladder cancers start in the innermost lining of the bladder, which is called the urothelium or transitional epithelium. As the cancer grows into or through the other layers in the bladder wall, it has a higher stage, becomes more advanced, and can be harder to treat. More...08 Jan 2020
Cardiac Blood Test Predicts Post-Surgical Outcomes
Globally, of the 200 million adults who undergo major surgery, 18% will experience serious cardiac and vascular complications including death within 30 days following their intervention, such as hip and knee replacements, bowel resections and abdominal aortic aneurysm repair. More...08 Jan 2020
Extrachromosomal Circular DNA Drives Oncogenic Genome Remodeling in Neuroblastoma
Circularized DNA falling outside of linear chromosomes may serve as a recurrent source of somatic rearrangements in neuroblastoma, a pediatric cancer affecting immature cells in the sympathetic nervous system. More...02 Jan 2020
Liquid Biopsy Detects Breast Cancer Residual Disease
The concept of circulating DNA or tumor cells to identify patients with residual cancer present after early-stage, putatively curative treatment has made rapid strides across multiple tumor types since some of the first promising tests in colorectal cancer. More...02 Jan 2020
Standard Pathology Tests Outperform Molecular Subtyping in Bladder Cancer
Evolving diagnostic approaches include compiling databanks on gene expression and mutations present in a cancer type to find patterns of gene expression that are then used to subtype tumors that "pathologically look similar" but are molecularly different. More...02 Jan 2020
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Innovative Blood Test Aids Early Detection of Breast Cancer
Aqueous Humor Is Superior to Blood to Diagnose Retinoblastoma
Automated Immunoassay Systems Evaluated for KL‐6 Antigen Quantification
High Levels Of Blood Hormones Raise Prostate Cancer Risk
Prostate Cancer Methylation Levels Linked to Epigenetic Profiles
Metastatic Tumor Profiles Lead to Potential Treatment Targets
Full Analytical Data Validated for Target Selector ctDNA Assays
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.