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Image: The SpiroNose (generic name: “eNose”) linked to the online BreathBase platform analyzes the mixture of volatile organic compounds (VOCs) in exhaled breath in real-time based on advanced signal processing and an extensive online reference database, infused with AI (Photo courtesy of Breathomix)

Electronic Nose Technology May Facilitate Accurate Diagnosis of Sarcoidosis

Sarcoidosis is a granulomatous inflammatory disease without a known cause that can affect roughly any organ. The lungs are involved in the vast majority of patients (89% to 99%). Diagnosis can be challenging because no standardized diagnostic procedure exists. The three major criteria for diagnosis are compatible clinical features, pathology tissue assessment, and exclusion of other granulomatous diagnoses. More...
12 Apr 2022
Image: Visualizing the invisible: New fluorescent DNA label reveals nanoscopic cancer features using a custom-built system on the Olympus IX71 Inverted Microscope (Photo courtesy of Fluorescence Microscopes)

New Fluorescent DNA Label Reveals Nanoscopic Cancer Features

Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk. More...
15 Mar 2022
Image: PyroMark Q96 ID instrument for quantitative analysis of genetic or epigenetic DNA modifications using Pyrosequencing technology (Photo courtesy of Karolinska Institutet)

Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis (

Differential leukocyte counts are usually measured based on cellular morphology or surface marker expression. It has recently been shown that leukocyte counts can also be determined by cell-type–specific DNA methylation (DNAm). Such epigenetic leukocyte counting is applicable to small blood volumes and even frozen material, but for clinical translation, the method needs to be further refined and validated. More...
14 Mar 2022
Image: A `lab-in-a-box`, the PLUM reader (Portable, Low-cost, User-friendly, Multimode), presents results from up to 384 patient samples and displays them in a single image capture (Photo courtesy of Livia Guo, LSK Technologies)

Paper-Based Portable Diagnostic Platform Accurately Detects Mosquito-Borne Diseases Under Field Conditions

Field trails conducted in Latin America have shown that a paper-based portable diagnostic platform could accurately detect patients with mosquito-borne diseases with sensitivities equivalent to laboratory PCR tests. More...
09 Mar 2022
Image: ASSIST PLUS pipetting robot with D-ONE single channel pipetting module (Photo courtesy of INTEGRA Biosciences)

Single Channel Pipetting Module Enables Hands-Free Transfers from Individual Tubes or Wells

A new single channel pipetting module for hands-free transfers from individual tubes or wells effectively automates tedious tasks such as serial dilutions, sample normalization, hit picking or pipetting of complex plate layouts, thereby increasing productivity and reproducibility in the lab while reducing hands-on time, processing errors and physical strain. More...
01 Mar 2022
Image: A new blood-clotting test that uses only a single drop of blood and a smartphone with a plastic attachment that holds a tiny cup beneath the phone’s camera (Photo courtesy of Mark Stone/University of Washington)

Micro-Mechanical Blood Clot Testing Using Smartphones

Researchers have developed a new blood-clotting test that uses only a single drop of blood and a smartphone vibration motor and camera. More...
23 Feb 2022
Image: The Xpert Xpress Flu/RSV Assay is intended as an aid in the diagnosis of influenza and respiratory syncytial virus infections (Photo courtesy of Cepheid)

P-O-C Assay Detects Respiratory Syncytial Virus in Older Adults

The point-of-care Xpert Xpress Flu/RSV test appeared nearly as accurate as routine real-time RT-PCR for detecting respiratory syncytial virus (RSV) infections in older adults, a Dutch study found. More...
22 Feb 2022
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.