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Microbiology

Image: The Mini8 Plus real time polymerase chain reaction (RT-PCR) thermocycler (Photo courtesy of Coyote Bioscience).

Direct Molecular Assay Developed for Zika Diagnosis

Zika virus (ZIKV), a mosquito-borne Flavivirus, is a positive single-stranded RNA virus with a nucleic acid length of about 10.7kb. This virus has been spreading rapidly and there have been large-scale outbreaks worldwide in recent years. ZIKV has drawn attention as it may cause severe symptoms while no specific medical treatment or vaccine is currently available. More...
14 Aug 2019
Image: The GeneXpert MTB/RIF assay is designed as a rapid diagnosis test of Tuberculosis (TB) and drug resistance (Photo courtesy of Cepheid).

Serum Siderocalin Measured in Patients with TB and HIV

Tuberculosis (TB) continues to be a significant cause of morbidity and mortality worldwide. The progression from uninfected or latently infected to active TB is often insidious and has minimal symptoms in the initial months, resulting in delayed diagnosis and poor outcomes. More...
14 Aug 2019
Image: The BC-6800 benchtop automatic hematology analyzer (Photo courtesy of Mindray).

Hematology Analyzer Screens for Malaria in Clinical Setting

Malaria is a vector-borne infectious disease that continues to have high morbidity and mortality globally. Diagnosis based only on clinical symptoms has very low specificity as there is no combination of symptoms that reliably distinguishes malaria from other causes of fever or influenza. More...
14 Aug 2019
Image: A colored scanning electron micrograph (SEM) of Enterococcus faecalis. These bacteria generate 12,13-diHOME and the concentration of the lipid itself in the babies’ stool samples predicted which infants went on to develop allergies (Photo courtesy of Pete Wardell/CDC).

Allergy Risk Increased by Compound Found in Infant Gut

Gut microbiota (formerly called gut flora) is the name given today to the microbe population living in our intestine. A recent study of newborn infants has identified a compound produced by gut bacteria that appears to predispose certain infants to allergies and asthma later in life. More...
14 Aug 2019
Image: Burkholderia pseudomallei colonies grown on Ashdown\'s agar after four days incubation showing the characteristic cornflower head morphology (Photo courtesy of Gavin Koh).

Cost-Effectiveness of Media for Melioidosis Diagnosis Reviewed

Melioidosis is a frequently fatal disease caused by a soil bacterium called Burkholderia pseudomallei that is widespread in the rural tropics. The yield of B. pseudomallei from sites with a normal flora is increased by culture using selective, differential media such as Ashdown’s agar and selective broth. More...
09 Aug 2019
Image: The device without a smartphone (left) and with a smartphone attached (right) (Photo courtesy of Rohan Mehra - Division for Strategic Public Relations).

Smartphone-Based Device Used for Influenza Virus Detection

A simple and inexpensive smartphone-based device was able to detect influenza virus particles in clinical samples with almost 100 times greater sensitivity than commercial rapid influenza diagnostic tests. More...
05 Aug 2019
Image: Bacteria in the gut are pulled into the helical channels by an osmotic “pump” generated by a calcium salt-filled chamber within the pill (Photo courtesy of Nano Lab, Tufts University).

Novel Diagnostic Device Profiles Population of Gut Microbiome

Researchers used a three-dimensional (3D) printer to manufacture a novel pill-like diagnostic tool capable of profiling the bacterial species comprising the gut microbiome in the critical area between the stomach and the colon. More...
05 Aug 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.