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Microbiology

Image: Integrating programmable DNAzymes with electrical readout for rapid and culture-free bacterial detection using a handheld platform (Photo courtesy of McMaster University)

New Technology Can Diagnose Infections in Minutes

The detection and identification of bacteria currently rely on enrichment steps such as bacterial culture and nucleic acid amplification to increase the concentration of target analytes. These steps increase assay time, cost and complexity, making it difficult to realize a truly rapid point-of-care test. More...
08 Jul 2021
Image: The Luminex200 Instrument System sets the standard for multiplexing, providing the ability to perform up to 100 different tests in a single reaction volume on a flow cytometry-based platform (Photo courts of Luminex Corporation)

Biological Markers Associated with Severe Dengue Identified

Dengue is the most common mosquito-borne viral disease to affect humans globally. In 2019, the World Health Organization identified dengue as one of the top 10 threats to global health, with transmission occurring in 129 countries and an estimated 3.9 billion people being at risk. More...
06 Jul 2021
Image: The MicroIDSys Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) system (Photo courtesy of ASTA Corp)

Direct Bacterial Identification and Antimicrobial Susceptibility Test Evaluated

Rapid and accurate microbial identification and antimicrobial susceptibility testing (AST) are essential for timely use of appropriate antimicrobial agents for bloodstream infection. Rapid, accurate diagnostic tests, and innovative treatments constitute the key for improvement of bloodstream infection outcome. More...
01 Jul 2021
Image: The Bioanalyzer RNA 6000 Nano assay provides reliable and reproducible characterization of total RNA and mRNA from multiple sample types, from as low as 5 ng of total RNA (Photo courtesy of Agilent)

Respiratory Syncytial Virus Bronchiolitis Has Different Subtypes

Bronchiolitis is the leading cause of hospitalization in infants in the USA, accounting for about 110,000 hospitalizations annually. In addition to the substantial acute morbidity, around 30% of infants hospitalized for bronchiolitis (“severe bronchiolitis”) subsequently develop asthma in childhood. More...
30 Jun 2021
Image: Xpert MTB/RIF Ultra assay is an automated molecular test that has improved the detection of tuberculosis and rifampicin resistance (Photo courtesy of Cepheid)

Highly Sensitive Molecular Test Detects Cases of Tuberculosis

Tuberculosis (TB) is a bacterial infection spread through inhaling tiny droplets from the coughs or sneezes of an infected person. It mainly affects the lungs, but it can affect any part of the body, including the tummy (abdomen), glands, bones and nervous system. More...
28 Jun 2021
Image: A molecular model of the spike proteins (red) of SARS-CoV-2 binding to the angiotensin-converting enzyme 2 (ACE2) protein, the receptor (blue) which is it’s entry route to the target cell (Photo courtesy of the Juan Gaertner/ Science Photo Library)

Plasma ACE2 Predicts Prognosis of COVID-19 Hospitalized Patients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a devastating global pandemic. The disease caused by SARS-CoV-2 infection has been termed coronavirus disease of 2019 (COVID-19) with clinical manifestations ranging from asymptomatic and subclinical infection to severe hyperinflammatory syndrome and death. More...
24 Jun 2021
Image: The OnSite Dengue Ag Rapid Test is a lateral flow chromatographic immunoassay for the qualitative detection of dengue NS1 antigen (DEN1, 2, 3, 4) in human serum, plasma or whole blood (Photo courtesy of CTK BioTech)

Novel Dengue Virus IgG Rapid Diagnostic Test Evaluated

Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. More...
16 Jun 2021
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.