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Microbiology

Image: Photomicrograph of Mycobacterium tuberculosis - Ziehl-Neelsen Acid-Fast Stains bacteria red (Photo courtesy of Rockefeller University)

Potential Immune Markers Found for Active Tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those affected. More...
18 May 2021
Image: Results of the Recombinase Polymerase Amplification-Lateral Flow (RPA-LF) assay for cutaneous leishmaniasis (Photo courtesy of University of Texas Medical Branch)

RPA-LF Assay Evaluated for Cutaneous Leishmaniasis in Colombia

Cutaneous leishmaniasis (CL) is a recognized public health challenge in the Americas, with an average of 55,000 cases per year between 2001 and 2018 in 17 countries of the region. Most cases (79.4%) have been acquired in and continue to occur in rural areas. More...
17 May 2021
Image: BinaxNOW COVID-19 Ag Cards (Photo courtesy of Abbott Laboratories)

Serial SARS-CoV-2 Rapid Antigen Testing Evaluated During Outbreaks

Serial, facility-wide testing for SARS-CoV-2 can help identify cases in outbreak settings, allowing for rapid implementation of transmission-based precautions and infection prevention and control strategies. More...
13 May 2021
Image: Schematic diagram of a rich meconium metabolome in human infants is associated with early-life gut microbiota composition and reduced allergic sensitization (Photo courtesy of University of British Columbia)

Meconium Microbiome Can Help Predict Risk of Developing Allergies

Meconium, which is typically passed within the first day of life, is made up of a variety of materials ingested and excreted during development, ranging from skin cells, amniotic fluid and various molecules known as metabolites. More...
12 May 2021
Image: The AMPLIX real-time polymerase chain reaction system (Photo courtesy of Biosynex)

LAMP Assay Developed to Diagnose High HBV DNA Levels

Worldwide, 257 million people are chronically infected with hepatitis B virus (HBV) and 887,000 annually die from cirrhosis or liver cancer. Since more than 95% of HBV-infected people live in low-income and middle-income countries (LMICs) and only 12-25% of infected people are eligible for anti-HBV therapy. More...
05 May 2021
Image: Histopathology of the lung showing diffuse alveolar damage seen in patients who are infected with the COVID-19 virus (Photo courtesy of Sanjay Mukhopadhyay, MD)

Genetic Factors Linked to Severe COVID-19, Viral Infections in Children

Although children, in general, are thought to experience relatively mild infections with SARS-CoV-2, a subset of infected children do become very ill and develop a condition known as Multisystem Inflammatory Syndrome in Children (MIS-C). More...
29 Apr 2021
Image: A 47-year-old man with mucormycosis and (b) electron micrograph of his skin showing sporangia of Mucorales fungi: non-apophysate sporangia with pronounced columellae and conspicuous collarette at the base of the columella following sporangiospore dispersal (Photo courtesy of IntechOpen Limited)

Different Methods Compared for Isolating Fungal DNA

Mucormycosis (previously called zygomycosis) is a serious, but rare fungal infection, caused by a group of molds called mucormycetes. These molds live throughout the environment. Mucormycosis mainly affects people who are immunocompromised or diabetic. More...
26 Apr 2021
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