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Immunology

Image: Isoelectric focusing on agarose gel for immunoglobulins: a) Original scanned color image, b) gray scale image (Photo courtesy of the Catholic University of Lille).

Images Evaluated for CSF Electrophoresis of IgG Bands

Multiple sclerosis (MS) involves inflammatory lesions of white matter in the central nervous system (CNS) that spread over time. In MS immune reactions lead to intrathecal synthesis of specific immunoglobulins (IgGs) that can be detected in biological fluid samples both quantitatively and qualitatively by isoelectric focusing of supplementary oligoclonal IgG bands. More...
02 Jan 2018
Image: A diagram depicting high internal/external surface area ratio and binding capacity of nanocages. Affinity ligands covalently immobilized in the inner volume establish high-affinity noncovalent interaction with tuberculosis (TB) antigens (Photo courtesy of George Mason University).

Urine Test Developed for Accurate TB Detection

An accurate screening test for active pulmonary tuberculosis (TB) is urgently needed for patients who are not co-infected with human immunodeficiency virus (HIV). Worldwide, TB is one of the most prevalent bacterial infections, with the highest mortality in developing countries. More...
28 Dec 2017
Image: A photomicrograph of a dendritic cell (green) infected by Toxoplasma gondii (red) (Photo courtesy of The Wenner-Gren Institute).

Researchers Decode Toxoplasmosis’ Control of Immune Cells

The infection toxoplasmosis is caused by the parasite Toxoplasma gondii and is widely spread. It is estimated that 30%-50% of the global human population are carriers. Cats are the parasites' main host, but the infection is also spread among other animals, including humans. More...
20 Dec 2017
Image: The Neurofilament light (NF-L) ELISA allows fast quantification in less than three hours of NF-L in cerebrospinal fluid (Photo courtesy of UmanDiagnostics).

Blood Test Monitors Nerve Protein in MS Patients

Multiple sclerosis is a chronic inflammatory disease of the central nervous system (CNS) in which neuronal damage is present at an early stage. Due to both unpredictable and heterogeneous disease course and treatment response, biomarkers reflecting these processes are highly sought after. More...
12 Dec 2017
Image: The Access Hybritech new p2PSA test, part of the Prostate Health Index (phi) (Photo courtesy of Beckman Coulter).

Physicians Perform Fewer Prostate Biopsies Post-Phi Testing

Prostate cancer is the third-leading cause of cancer death in men, with one in seven receiving a diagnosis during his lifetime. In 2017, approximately 161,360 new cases of prostate cancer were identified, with 60% of those occurring in men 65 years of age or older. More...
04 Dec 2017
Image: The INNOTEST β-AMYLOID(1-42) is a solid-phase enzyme immunoassay for the quantitative determination of β-amyloid(1-42) in human cerebrospinal fluid (CSF) (Photo courtesy of Fujirebio Diagnostics).

New Immunoassays Measures Beta-Amyloid 42 in CSF

Cerebrospinal fluid (CSF) β-amyloid (Aβ) 42 and amyloid positron emission tomography (PET) have proved to have high diagnostic accuracy for Alzheimer disease (AD) years before the onset of clinical symptoms and are becoming an important part of the diagnostic workup. More...
30 Nov 2017
Image: The ARCHITECT i2000SR immunoassay analyzer (Photo courtesy of Abbott).

Newly Developed Automated Immunoassay Analyzed

Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted treatments. More...
29 Nov 2017
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.