Immunology
Maternal Multiomic Changes Could Predict Onset of Labor
Currently, predictions of when labor will start are imprecise and based on gestational age and an average pregnancy length of 40 weeks, even though the onset of labor between week 37 and 42 of pregnancy is considered normal. Having a better idea of when labor may arrive could help with planning and managing medical concerns like fetal lung maturation. More...18 May 2021
Gel and Capillary Electrophoresis Compared for Human Proteins
The electrophoresis of serum proteins remains a laboratory cornerstone for the diagnosis and monitoring of patients with plasma cell disorders, such as monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenström macroglobulinemia, and AL amyloidosis. More...12 May 2021
Developed Immunoassay Predicts Benefits of Anti-PD-1 Therapy in NSCLC
Lung cancer is the most common cause of cancer-related deaths worldwide. However, current targeted therapies and immunotherapies have gradually improved patient survival. Anti-programmed cell death-1 (PD-1) antibodies (Abs) are key drugs in non-small-cell lung cancer treatment; however, clinical benefits with anti-PD-1 monotherapy are limited. More...12 May 2021
Synovial Fluid Neutrophils Phenotyped in Oligoarticular Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is an inflammatory rheumatic joint disease affecting children. Despite disease onset being at a young age, symptoms may be lifelong and include irreversible joint damage or growth disturbances. More...29 Apr 2021
ANGPTL8 Levels Associated with Hyperlipidemia in Primary Nephrotic Syndrome
The typical clinical manifestations of Primary Nephrotic Syndrome (PNS) include massive proteinuria, hypoproteinemia, edema and/or hyperlipidemia. Of these, marked proteinuria is the core clinical manifestation, and its severity often parallels the degree of hyperlipidemia. More...28 Apr 2021
Serum α-L-Fucosidase Activity Measured for COVID-19 Infection
An unusual fucosylated LacdiNAc in the receptor-binding domains of the spike protein of COVID-19 has been observed. Reduced fucosylation was also found in a specific Fc domain of IgG antibodies in COVID-19 patients that enhanced the interactions with the activating FcγR, FcγRIIIa. More...22 Apr 2021
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In Other News
Urinary Heat Shock Protein 70 Evaluated in Chronic Prostatitis
Breath Test Determines Severity of Methylmalonic Acidemia Disease
Snibe Diagnostic’s Maglumi HIV Ab/Ag Combi CLIA Assay (4th-Generation) Secures CE Mark (List A)
Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality
T Cells Recognize Recent SARS-CoV-2 Variants
Type 1 Diabetes Onset Preceded by Gene Expression Changes
Serious Infections Prevalent in ANCA-Associated Vasculitis
Immunoassay Developed for Quantitative Detection of Serum Interleukin‐6
Performance of Five Lipoprotein(a) Immunoassays Evaluated
Flow-Cytometric Expression of Endoglin Assessed in B-Acute Lymphoblastic Leukemia
Toxoplasmosis Immune Status in Pregnancy Determined by Immunochromatography Assay
Toxoplasmic Encephalitis in HIV Patients Detected in Urine
Paraproteins Identification Methods Compared for Monoclonal Gammopathies
Chemiluminescence Anti‐Müllerian Hormone Assay Performance Characterized
Cardiac Troponins Assessed for Acute Heart Failure
Biomarker Protein Investigated in Juvenile Idiopathic Arthritis
Immune Response to Insulin Identifies Risk of Juvenile-Diabetes
Fibrinogen to Albumin Ratio Reflects ANCA‐Associated Vasculitis Activity
Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients
Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease
Urinary Antigen Test Kit Evaluated for Diagnosing Legionella Pneumonia
Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma
T Cell Response Profiled in COVID-19 Patients
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.