Hematology
Next Generation Sequencing Finds More Gene Mutations for Leukemia
Myeloid malignancies are characterized by uncontrolled proliferation and/or defects in differentiation of abnormal myeloid progenitor cells. Myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs) are often thought to be precursors to a higher grade myeloid malignancies, namely acute myeloid leukemia (AML). More...18 Feb 2021
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and currently the third leading cause of cancer deaths in the USA. Despite the fact that it only accounts for about 3% of new cancer cases, it is responsible for more than 7% of all cancer deaths, and only10% of patients survive five years with the disease. More...17 Feb 2021
Automated Leucocyte VCS Parameters Evaluated for Pathogenic Infections
Malaria and dengue are highly endemic in most parts of India. Mangalore, a city in coastal Karnataka, India, has high prevalence of both these vector‐borne infections with extensive range of clinical presentations. The outbreak of these infections is common during and after the rainy season. More...16 Feb 2021
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
Mild to moderate bleeding disorders (MBDs) are characterized by symptoms such as epistaxis, easy bruising, or menorrhagia, but bleeding can also be severe under certain circumstances such as hemorrhage after surgery or birth. More...11 Feb 2021
RDW Levels Associated with Adverse Outcomes in COVID-19 Patients
The red cell distribution width (RDW) blood test measures the amount of red blood cell variation in volume and size. RDW is not used as an isolated parameter when interpreting a complete blood count (CBC); instead, it provides shades of meaning in the context of the hemoglobin (Hgb) and mean corpuscular value (MCV). More...04 Feb 2021
ABO Histo-Blood Groups Influence Makeup of Gut Microbiome
Recent genome-wide association studies yielded inconsistent, underpowered and rarely replicated results such that the role of human host genetics as a contributing factor to microbiome assembly and structure remains uncertain. More...01 Feb 2021
Specific RUNX1 Mutations Cause Different Disease Types
Mutations of the hematopoietic master regulator RUNX1 are associated with acute myeloid leukemia, familial platelet disorder and other hematological malignancies whose phenotypes and prognoses depend upon the class of the RUNX1 mutation. More...28 Jan 2021
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In Other News
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Coagulopathy Testing Linked to Better COVID-19 Outcomes
Preterm Infants Tolerate Restrictive Red Blood Cell Transfusion Strategy
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Automated Hematologic Reference Intervals Defined for Newborns
Blood Type Linked to Risk of COVID-19 Infection Severity
Chronic Lymphocytic Leukemia Increases Peripheral Blood Hematopoietic Stem Cells
Next-Generation Sequencing Detects Residual Disease in Acute Lymphoblastic Leukemia
Elevated Soluble C5b9 Biomarker Found in SARS-CoV-2 Infected Children
Two Automated Hematology Analyzers Compared for Performance
Diagnostic Assays Evaluated for Vitamin B12 and Folate Deficiency
Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies
Anticoagulant Adjustment Evaluated Using Different Prothrombin Time Tests
CD200 Expression Marks Leukemia Stem Cells in Human AML
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
Paper Diagnostic Directly Measures Fibrinogen in Whole Blood
Newborns Getting Preoperative Blood Transfusions Have More Complications
Single-Cell Sequencing Reveals Clonal Diversity Among AML Patients
Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes
New Technology Rapidly Diagnoses Sickle Cell Disease
Methods for Automated Anti-Neutrophil Cytoplasmic Antibodies Compared
Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma
Elevated Clotting Factor V Found with Severe COVID-19
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
