Hematology

Automated Leucocyte VCS Parameters Evaluated for Pathogenic Infections
Malaria and dengue are highly endemic in most parts of India. Mangalore, a city in coastal Karnataka, India, has high prevalence of both these vector‐borne infections with extensive range of clinical presentations. The outbreak of these infections is common during and after the rainy season. More...16 Feb 2021

TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
Mild to moderate bleeding disorders (MBDs) are characterized by symptoms such as epistaxis, easy bruising, or menorrhagia, but bleeding can also be severe under certain circumstances such as hemorrhage after surgery or birth. More...11 Feb 2021

RDW Levels Associated with Adverse Outcomes in COVID-19 Patients
The red cell distribution width (RDW) blood test measures the amount of red blood cell variation in volume and size. RDW is not used as an isolated parameter when interpreting a complete blood count (CBC); instead, it provides shades of meaning in the context of the hemoglobin (Hgb) and mean corpuscular value (MCV). More...04 Feb 2021

ABO Histo-Blood Groups Influence Makeup of Gut Microbiome
Recent genome-wide association studies yielded inconsistent, underpowered and rarely replicated results such that the role of human host genetics as a contributing factor to microbiome assembly and structure remains uncertain. More...01 Feb 2021

Specific RUNX1 Mutations Cause Different Disease Types
Mutations of the hematopoietic master regulator RUNX1 are associated with acute myeloid leukemia, familial platelet disorder and other hematological malignancies whose phenotypes and prognoses depend upon the class of the RUNX1 mutation. More...28 Jan 2021

Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Fanconi anemia (FA) is a complex genetic disorder frequently associated with progressive marrow failure and a strong predisposition to early malignancies, particularly squamous cell carcinomas and hepatocellular carcinomas. More...20 Jan 2021

Coagulopathy Testing Linked to Better COVID-19 Outcomes
Significant infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to development of coagulopathy, most typically a hypercoagulable state. In addition to thrombotic conditions, coronavirus disease 2019 (COVID-19) patients may develop hemorrhagic complications, which have been under recognized or inadequately emphasized in prior studies. More...19 Jan 2021
In Other News
Preterm Infants Tolerate Restrictive Red Blood Cell Transfusion Strategy
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Automated Hematologic Reference Intervals Defined for Newborns
Blood Type Linked to Risk of COVID-19 Infection Severity
Chronic Lymphocytic Leukemia Increases Peripheral Blood Hematopoietic Stem Cells
Next-Generation Sequencing Detects Residual Disease in Acute Lymphoblastic Leukemia
Elevated Soluble C5b9 Biomarker Found in SARS-CoV-2 Infected Children
Two Automated Hematology Analyzers Compared for Performance
Diagnostic Assays Evaluated for Vitamin B12 and Folate Deficiency
Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies
Anticoagulant Adjustment Evaluated Using Different Prothrombin Time Tests
CD200 Expression Marks Leukemia Stem Cells in Human AML
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
Paper Diagnostic Directly Measures Fibrinogen in Whole Blood
Newborns Getting Preoperative Blood Transfusions Have More Complications
Single-Cell Sequencing Reveals Clonal Diversity Among AML Patients
Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes
New Technology Rapidly Diagnoses Sickle Cell Disease
Methods for Automated Anti-Neutrophil Cytoplasmic Antibodies Compared
Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma
Elevated Clotting Factor V Found with Severe COVID-19
RBC Distribution Width Associated with COVID-19 Mortality Risk
Microfluidic Label-Free Bioprocessing of Reticulocytes from Erythroid Culture
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.