Hematology
Chronic Lymphocytic Leukemia Increases Peripheral Blood Hematopoietic Stem Cells
Chronic lymphocytic leukemia (CLL) is an indolent B-cell malignancy invariably infiltrating the bone marrow. The disease remains incurable, and after emergence of therapy, resistant disease patients succumb to infections because of secondary bone marrow failure. More...31 Dec 2020
Next-Generation Sequencing Detects Residual Disease in Acute Lymphoblastic Leukemia
The use of next-generation sequencing (NGS) to detect residual disease in acute lymphoblastic leukemia (ALL) patients after treatment can better gauge their risk of relapse and overall survival than multiparameter flow cytometry. More...24 Dec 2020
Elevated Soluble C5b9 Biomarker Found in SARS-CoV-2 Infected Children
Most children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have mild or minimal disease, with a small proportion developing severe disease or multisystem inflammatory syndrome in children (MIS-C). More...21 Dec 2020
Two Automated Hematology Analyzers Compared for Performance
A complete blood count (CBC) is a highly automated laboratory test. The use of highly advanced measurement methods increases the accuracy and sensitivity of the determination of individual hematological parameters, especially in the case of white blood cells differentiation. More...17 Dec 2020
Diagnostic Assays Evaluated for Vitamin B12 and Folate Deficiency
Current guidelines pertaining to diagnosing macrocytic anemia in association with vitamin B12 and folate deficiency recommend that vitamin B12, folate, homocysteine, and methylmalonic acid assays should be assessed concurrently due to their close relationship in metabolism. More...07 Dec 2020
Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies
Myeloid malignancies are clonal diseases of hematopoietic stem or progenitor cells. Myeloid malignancies, including acute myeloid leukemia (AML), arise from the expansion of these hematopoietic stem and progenitor cells that acquire somatic mutations. More...01 Dec 2020
Anticoagulant Adjustment Evaluated Using Different Prothrombin Time Tests
Preanalytical variables may affect the results of routine coagulation assays. One important variable is hematocrit (Ht), which affects coagulation testing results. A sample with high Ht has lower plasma quantity, resulting in a dilution effect on the sample by an excess of the anticoagulant sodium citrate. More...26 Nov 2020
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In Other News
CD200 Expression Marks Leukemia Stem Cells in Human AML
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
Paper Diagnostic Directly Measures Fibrinogen in Whole Blood
Newborns Getting Preoperative Blood Transfusions Have More Complications
Single-Cell Sequencing Reveals Clonal Diversity Among AML Patients
Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes
New Technology Rapidly Diagnoses Sickle Cell Disease
Methods for Automated Anti-Neutrophil Cytoplasmic Antibodies Compared
Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma
Elevated Clotting Factor V Found with Severe COVID-19
RBC Distribution Width Associated with COVID-19 Mortality Risk
Microfluidic Label-Free Bioprocessing of Reticulocytes from Erythroid Culture
New Diagnosed Anemia Linked to Crohn’s Disease Risk
Hematological Parameters Evaluated for Cervicocranial Arterial Dissection Stroke
Quantitative Agglutination Determined on Automatic Hematology Analyzer
Complex ABO Glycan Phenotypes Predicted by Lectin Microarrays
Positive Lymphocyte Gene Rearrangement Evaluated for Hematologic Malignancies
Lymphocyte Count Correlated to Comorbid Diabetes and COVID-19
Clonal Hematopoiesis Prevalence Determined in Healthy Donors
Hodgkin Lymphoma Therapy Response Linked to T-Cell Receptor Repertoire
Microfluidic Device Explores Ovarian Cancer Interactions
Biomarkers Evaluated for Severity of Diabetic Kidney Disease
Nanoparticle System Captures Heart-Disease Biomarker From Blood
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.