Hematology
Genome Sequencing More Informative than Cytogenetic Analysis in Myeloid Cancers
Genetic profiling is a routine component of the diagnostic workup for an increasing number of cancers and is used to predict clinical outcomes and responses to targeted therapies. Genomic analysis is essential for risk stratification in patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). More...24 Mar 2021
Genetic Mutations Identified for Rare VEXAS Syndrome
VEXAS syndrome is a serious inflammatory condition which develops in men over 50, causing them to become very sick and fatigued, and can be fatal. It was originally thought to be rare, but a new study has identified genetic mutations which indicate that the disease is actually much more common. More...23 Mar 2021
Paraproteins Identification Methods Compared for Monoclonal Gammopathies
Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. More...18 Mar 2021
Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers
Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by detectable hematopoietic-associated gene mutations in a person without evidence of hematologic malignancy. Somatic mutations at hotspots (genetic loci observed to be frequently mutated across cancer patients) often drive or contribute to cancer pathogenesis. More...16 Mar 2021
COVID-19 Induces a Hyperactive Phenotype in Circulating Platelets
Coronavirus Disease 2019 (COVID-19) is characterized by a marked pro-inflammatory response with fever, elevated inflammatory markers, and clinical and radiological features of pneumonitis being evident among affected individuals. More...15 Mar 2021
Hemoglobin Levels Measured with AI Microscope, Microfluidic Chips
A complete blood count can help ascertain the health of a patient and typically includes an estimate of the hemoglobin concentration, which can indicate several conditions, including anemia, polycythemia, and pulmonary fibrosis. More...10 Mar 2021
Blood Tests Offer Early Indicator of Severe COVID-19
For most patients, COVID-19 manifests as an upper respiratory tract infection that is self-limited. However, the progression of COVID-19 in a large subset of patients to respiratory distress, multiorgan failure, and death has resulted in an enormous global impact. More...09 Mar 2021
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In Other News
Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients
Next Generation Sequencing Finds More Gene Mutations for Leukemia
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Automated Leucocyte VCS Parameters Evaluated for Pathogenic Infections
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
RDW Levels Associated with Adverse Outcomes in COVID-19 Patients
ABO Histo-Blood Groups Influence Makeup of Gut Microbiome
Specific RUNX1 Mutations Cause Different Disease Types
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Coagulopathy Testing Linked to Better COVID-19 Outcomes
Preterm Infants Tolerate Restrictive Red Blood Cell Transfusion Strategy
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Automated Hematologic Reference Intervals Defined for Newborns
Blood Type Linked to Risk of COVID-19 Infection Severity
Chronic Lymphocytic Leukemia Increases Peripheral Blood Hematopoietic Stem Cells
Next-Generation Sequencing Detects Residual Disease in Acute Lymphoblastic Leukemia
Elevated Soluble C5b9 Biomarker Found in SARS-CoV-2 Infected Children
Two Automated Hematology Analyzers Compared for Performance
Diagnostic Assays Evaluated for Vitamin B12 and Folate Deficiency
Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies
Anticoagulant Adjustment Evaluated Using Different Prothrombin Time Tests
CD200 Expression Marks Leukemia Stem Cells in Human AML
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
