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Hematology

Image: Mutations in cell free DNA (cfDNA) or cells in the peripheral blood along with anemia or thrombocytopenia are the hallmark of myelodysplastic syndrome (MDS). The diagnosis of MDS is confirmed when mutations in hematopoietic cells are detected at relatively high levels (Photo courtesy of Genomic Testing Cooperative).

Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes

The age-related acquisition of somatic mutations that lead to clonal expansion in regenerating hematopoietic stem cell populations has recently been associated with both hematological cancer and coronary heart disease, and this phenomenon is termed clonal hematopoiesis of indeterminate potential (CHIP). More...
29 Oct 2020
Image: An Acousto Thermal Shift Assay `lab-on-a-chip` device shown next to a US quarter for size comparison. The device can diagnose sickle cell anemia (Photo courtesy of CU Boulder College of Engineering and Applied Science).

New Technology Rapidly Diagnoses Sickle Cell Disease

Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. The most common type is known as sickle cell anemia (SCA). It results in an abnormality in the oxygen-carrying protein hemoglobin found in red blood cells. More...
29 Oct 2020
Image: The EUROPattern Microscope Live: Ultrafast fluorescence microscopy that automatically detects anti-neutrophil cytoplasmic antibodies (Photo courtesy of EUROIMMUN AG).

Methods for Automated Anti-Neutrophil Cytoplasmic Antibodies Compared

The detection of anti-neutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence assays (IFA) is of diagnostic importance in vasculitis and some other inflammatory diseases. More...
21 Oct 2020
Image: Photomicrograph of histopathology of hepatocellular carcinoma, the most common form of primary liver cancer, showing end-stage cirrhosis - blue collagen (fibrosis) Mallory bodies; loss of normal liver architecture; and nuclear atypia. (Photo courtesy of Nephron).

Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is an inflammation-related cancer, where non-resolving inflammation contributes to its development and progression. Peripheral inflammatory cells have been shown to be associated with the prognosis of various types of cancer. More...
12 Oct 2020
Image: The ACL TOP 750 analyzer is for advanced automation and quality management in hemostasis testing (Photo courtesy of Instrumentation Laboratory).

Elevated Clotting Factor V Found with Severe COVID-19

Coagulopathy causes morbidity and mortality in patients with coronavirus disease 2019 (COVID‐19) due to severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection. Most doctors now know that COVID-19 can cause blood clots, potentially leading to paralysis, stroke, heart attack and death. More...
08 Oct 2020
Image: Scanning electron microscope image shows SARS-CoV-2 (yellow) the virus that causes COVID-19, isolated from a patient in the USA, emerging from the surface of cells (pink) cultured in the laboratory (Photo courtesy of NIAID-RML).

RBC Distribution Width Associated with COVID-19 Mortality Risk

COVID-19 has a high rate of hospitalization, critical care requirement, and mortality. Identifying patients at highest risk for severe disease is important to facilitate early, aggressive intervention and to manage local hospital resources to mitigate the critical care crises that have impacted some hospital systems. More...
06 Oct 2020
Image: Laboratory set-up of microfluidic sorting and purification of cells during red blood cell culture and manufacturing (Photo courtesy of Singapore-MIT Alliance for Research and Technology).

Microfluidic Label-Free Bioprocessing of Reticulocytes from Erythroid Culture

Blood transfusions save millions of lives every year, but over half the world's countries do not have sufficient blood supply to meet their needs. The ability to manufacture red blood cells (RBCs) on demand, especially the universal donor blood (O+), would significantly benefit those in need of transfusion. More...
30 Sep 2020
New
Gold Member
Hybrid Pipette
SWITCH
Collection and Transport System
PurSafe Plus®
Hemodynamic System Monitor
OptoMonitor
New
Gold Member
Collection and Transport System
PurSafe Plus®


The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.