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Molecular Diagnostics

Image: A diagram comparing normal and diseased in irritable bowel syndrome (Photo courtesy of HealthNormal).

Genetic Link to IBS Identified in Women

Irritable bowel syndrome is the most common gastrointestinal disorder. More than 10% of the population suffers from recurrent symptoms including abdominal pain, gas, diarrhea and constipation and it is more common in women than men. More...
18 Apr 2018
Image: A diagram of various stents used in angioplasty (Photo courtesy of Open Biomedical Initiative).

Genetic Test May Improve Post-Stent Treatment Outcome

A test for specific genetic mutations successfully informed blood-thinner treatment selection following stent placement to open clogged blood vessels, leading to significantly fewer complications. More...
17 Apr 2018

Amino Acids Can Predict CV Disease Risk in Women

Results of a recent study supported the hypothesis that plasma BCAAs (branched-chain amino acids) were positively associated with cardiovascular disease (CVD) risk and were linked to an intermediate diagnosis of type II diabetes (T2D). More...
16 Apr 2018
Image: The Genedrive PCR diagnostics platform (Photo courtesy of Genedrive).

Rapid Test Developed for Hepatitis C Infections

A rapid, point-of-care PCR-based diagnostic test will allow for the detection of occult hepatitis C virus (HCV) infections under both laboratory and field conditions. More...
16 Apr 2018
Image: The MinION is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Oxford Nanopore Technologies).

Nanopore Method Developed for Genetic Screening

Rapid sequencing of short DNA reads may be useful for a wide range of clinical applications including targeted mutation analysis, cancer-panel testing, and aneuploidy screening. Fast, point-of-care preimplantation genetic screening could improve the success of in vitro fertilization procedures by not requiring embryos to be frozen. More...
12 Apr 2018
Image: The GloMax Discover multimode microplate reader (Photo courtesy of Promega).

Aggressive Meningioma Linked to Transcription Factor Activity

Meningioma, a cancer of the cerebral and spinal meninges, is the most common primary CNS tumor in the USA. Meningioma is the most common primary intracranial tumor, but the molecular drivers of aggressive meningioma are incompletely understood. More...
12 Apr 2018
Image: The Ion Personal Genome Machine (PGM) System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data (Photo courtesy of Thermo Fisher Scientific).

Gut Microbiome Analysis Predicts Hospitalizations in Cirrhosis

Cirrhosis is a leading cause of mortality and healthcare expenditure due to hospitalizations worldwide. Bacterial products such as endotoxin play a key role in the development of a proinflammatory milieu and disease progression in cirrhosis. More...
11 Apr 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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