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Molecular Diagnostics

Image: Rheumatoid arthritis can cause a range of debilitating symptoms, including pain and swelling in the joints, tiredness and depression (Photo courtesy of SPL).

Gene Signatures and Biomarkers Predict RA Onset

Rheumatoid arthritis is characterized by joint inflammation leading to destruction of bone and cartilage. Since structural joint damage is irreversible, early recognition and treatment is a key focus in an effort to halt the progression of the disease. More...
28 Jun 2018
Image: The RNeasy MinElute cleanup kit (Photo courtesy of Qiagen).

Extracellular RNA Helps Diagnose Medical Conditions

For some diseases, biomarkers can be used to determine how far the illness has advanced, but not shed light on how quickly it will progress in the future. Circulating extracellular RNAs (exRNAs) have the potential to serve as biomarkers for a wide range of medical conditions. More...
28 Jun 2018
Image: Duolink proximity ligation assay technology extends the capabilities of traditional protein techniques (Photo courtesy of Olink Proteomics).

Genomic Atlas of Human Plasma Proteome Publicized

Although plasma proteins have important roles in biological processes and are the direct targets of many drugs, the genetic factors that control inter-individual variation in plasma protein levels are not well understood. More...
26 Jun 2018
Image: A gram stain of Klebsiella pneumoniae from a blood culture (Photo courtesy of Erasmus Medical Centre).

Metagenomics Uncover Pathogens and Drug-Resistance Genes

Metagenomics, and even metatranscriptomics, are enabling clinicians and scientists to tease out pathogens from an assortment of microbes. Scientists are beginning to show that metagenomics can pick up the same microbes that culturing does and may even spot ones missed by culturing. More...
26 Jun 2018
Image: A photomicrograph of a sputum specimen showing the presence of numerous Mycobacterium tuberculosis bacteria (Photo courtesy of the CDC).

Biomarker Panel Distinguishes TB from Other Infections

A small proof-of-principle study confirmed the validity of a 20-gene biomarker panel able to distinguish individuals with active or latent tuberculosis (TB) from those with viral or bacterial infections. More...
25 Jun 2018
Image: Peak flow meters, used to measure the peak expiratory flow rate in both monitoring and diagnosing asthma (Photo courtesy of Wikimedia Commons).

RNA Sequencing of Nasal Samples Used to Diagnose Asthma

A 90-gene biomarker panel has been established that enables the rapid, accurate diagnosis of asthma from simple nasal brush samples. More...
25 Jun 2018
Image: The new line of ELISA tests designed for neonatal screening is based on Dry Blood Spot (DBS) technology and comprises a menu of eight kits (Photo courtesy of Calbiotech).

ELISA-Based Neonatal Screening Line Offers Menu of Eight Kits

A recently released line of ELISA tests for neonatal screening is based on Dry Blood Spot (DBS) technology and comprises a menu of eight kits. The kits are the newest diagnostic assays being introduced by Calbiotech. More...
25 Jun 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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