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Molecular Diagnostics

Image: Whole genome genotyping arrays are an important tool for discovering variants that contribute to human disease (Photo courtesy of Megan Smolenyak, MBA).

New Genetic Risk Factors Identified for Peanut Allergy

Peanut allergy develops in early life and is rarely outgrown. Roughly 1% of Canadian adults and between 2% and 3% of Canadian children are affected, and the symptoms can be severe and even life threatening. More...
25 Oct 2017
Image: The HiSeq X Ten sequencing system (Photo courtesy of Illumina).

Whole Genome Sequencing Identifies New Autism Signature

Current genetic tests for autism scan broad portions of the genome for DNA insertions or deletions that have previously been linked to autism. Other tests look for changes in the DNA building blocks of certain genes, but these tests flag only about 10% to 30% of cases. More...
25 Oct 2017
Image: The Affymetrix Axiom CEU Genome-Wide Population-Optimized Human Arrays are genotyping panels that offer genetic coverage of rare and common variants for genome-wide disease association studies (Photo courtesy of Thermo Fisher Scientific).

New Risk Variants Identified for Restless Legs Syndrome

As many as one in ten people of European ancestry is affected by restless legs syndrome, in which sufferers feel an overwhelming urge to move, often in conjunction with unpleasant sensations, usually in the legs. More...
24 Oct 2017
Image: An ocular fundus aspect of retinoblastoma (Photo courtesy of Wikimedia).

Liquid Biopsy for Retinoblastoma Discovered

A new study indicates a proof-of-concept for a safe and effective way to derive genetic profile information from a retinoblastoma tumor without removing the eye. More...
24 Oct 2017
Image: An illustration of the human brain cerebral lobes: the frontal lobe (pink), parietal lobe (green), and occipital lobe (blue) (Photo courtesy of Wikimedia).

Genetic Decoding Improved for Neurodevelopmental Disorders

DLG2 gene study as a case in point that will help facilitate future diagnosis of children with neurodevelopmental disorders (NDDs), such as intellectual disability, autism, or early-onset symptoms of psychiatric diseases such as schizophrenia. More...
23 Oct 2017
Image: A photomicrograph showing histopathological image of cerebral glioblastoma (Photo courtesy of Wikimedia Commons).

Biomarker Predicts Cancer Aggressiveness and Drug Susceptibility

Researchers have identified a protein required by some forms of brain cancer (glioblastoma multiforme, GBM) that can be used as a predictive marker for aggressiveness and effective drug response. More...
23 Oct 2017
Image: Mitochondrial DNA comprises the small circular chromosome found inside the mitochondria (Photo courtesy of the U.S. National Human Genome Research Institute).

Mitochondrial DNA Copy Number Improves CVD Risk Prediction

Mitochondrial DNA copy number (mtDNA-CN), which represents the number of mitochondria per cell and number of mitochondrial genomes per mitochondrion, is an indirect biomarker of mitochondrial function that has been identified as an independent predictor of cardiovascular disease (CVD) risk. More...
23 Oct 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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