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Molecular Diagnostics

Measurement of Two Biomarkers Predicts Diabetes Risk

Results presented in a recently published study indicated that it is possible to predict likelihood of developing diabetes by measuring the levels of two biomarkers in a single blood sample. More...
03 Jul 2018
Image: Multiple bacilli (rod-shaped bacteria, here shown as black and bean-shaped) shown between white blood cells in urinary microscopy. These changes are indicative of a urinary tract infection (Photo courtesy of Wikimedia Commons).

UTIs Diagnosed with Genetic Analysis of Cell-Free DNA

Genetic analysis of cell-free DNA (cfDNA) in urine samples reveals valuable information, which enables comprehensive monitoring of host and pathogen dynamics in bacterial and viral urinary tract infections. More...
03 Jul 2018
Image: Rheumatoid arthritis can cause a range of debilitating symptoms, including pain and swelling in the joints, tiredness and depression (Photo courtesy of SPL).

Gene Signatures and Biomarkers Predict RA Onset

Rheumatoid arthritis is characterized by joint inflammation leading to destruction of bone and cartilage. Since structural joint damage is irreversible, early recognition and treatment is a key focus in an effort to halt the progression of the disease. More...
28 Jun 2018
Image: The RNeasy MinElute cleanup kit (Photo courtesy of Qiagen).

Extracellular RNA Helps Diagnose Medical Conditions

For some diseases, biomarkers can be used to determine how far the illness has advanced, but not shed light on how quickly it will progress in the future. Circulating extracellular RNAs (exRNAs) have the potential to serve as biomarkers for a wide range of medical conditions. More...
28 Jun 2018
Image: Duolink proximity ligation assay technology extends the capabilities of traditional protein techniques (Photo courtesy of Olink Proteomics).

Genomic Atlas of Human Plasma Proteome Publicized

Although plasma proteins have important roles in biological processes and are the direct targets of many drugs, the genetic factors that control inter-individual variation in plasma protein levels are not well understood. More...
26 Jun 2018
Image: A gram stain of Klebsiella pneumoniae from a blood culture (Photo courtesy of Erasmus Medical Centre).

Metagenomics Uncover Pathogens and Drug-Resistance Genes

Metagenomics, and even metatranscriptomics, are enabling clinicians and scientists to tease out pathogens from an assortment of microbes. Scientists are beginning to show that metagenomics can pick up the same microbes that culturing does and may even spot ones missed by culturing. More...
26 Jun 2018
Image: A photomicrograph of a sputum specimen showing the presence of numerous Mycobacterium tuberculosis bacteria (Photo courtesy of the CDC).

Biomarker Panel Distinguishes TB from Other Infections

A small proof-of-principle study confirmed the validity of a 20-gene biomarker panel able to distinguish individuals with active or latent tuberculosis (TB) from those with viral or bacterial infections. More...
25 Jun 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.