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Molecular Diagnostics

Image: A micrograph showing granulomatous inflammation of bladder neck tissue due to Bacillus Calmette-Guérin (BCG) used to treat bladder cancer (Photo courtesy of Wikimedia Commons).

New Test Predicts Potential Success of BCG Immunotherapy for Bladder Cancer

A laboratory test that measures the amount of IL2 secretion from CD4+ T cells after overnight in vitro incubation with tuberculin predicts the potential success of BCG (Bacille Calmette-Guérin) immunotherapy treatment for bladder cancer. More...
03 Sep 2018
Image: An illustration depicting a deep vein thrombosis (Photo courtesy of Wikimedia Commons).

Rapid Method Suggested for Diagnosis of DVT

A simple blood test has been proposed as an alternative to the fairly costly and time intensive ultrasound procedure for diagnosis of deep vein thrombosis (DVT). More...
03 Sep 2018
Image: Multiple myeloma, a cancer of the blood plasma (Photo courtesy of Medical News Today).

Multi-Omics Approach Guides Relapsed Multiple Myeloma Treatment

Many patients with relapsed multiple myeloma are not often matched with correct treatment options in a timely or personalized manner, and most patients have a median survival rate of six years. With standard diagnosis and treatment, relapses are usually inevitable and fatal for most patients. More...
30 Aug 2018
Image: The HiSeq X Five System enables ultra-high-throughput whole-genome sequencing at a cost and scale appropriate for large genome centers (Photo courtesy of Illumina).

Whole-Genome Sequencing Diagnoses Early Infantile Epileptic Encephalopathy

Early infantile epileptic encephalopathy (EIEE) is a rare epilepsy syndrome that causes intractable seizures with multiple seizure types and presents in the first months of life. While the prevalence of EIEE is unclear, and only affects a subset of all infants with seizures, infants with EIEE have serious medical complications. More...
30 Aug 2018
Image: Karyotyping of Trisomy 21 in a female: There is a full set of 23 homologous pairs of autosomes, but an extra chromosome 21 (Photo courtesy of Dr. Daniel Closa).

DNA Screening and Invasive Testing Show Similar Miscarriage Rates

Cell-free DNA (cfDNA) tests are increasingly being offered to women in the first trimester of pregnancies at a high risk of trisomy 21 to decrease the number of required invasive fetal karyotyping procedures and their associated miscarriages. More...
29 Aug 2018
Image: A photomicrograph of a myeloma colored with hematoxylin and eosin stain (Photo courtesy of Wikipedia Commons).

Improved Myeloma Diagnosis Based on Blood Count Components

A team of British researchers has found which blood tests could be useful for suggesting or excluding a diagnosis of myeloma. More...
27 Aug 2018
Image: The new Anti-Zika Virus IgAM ELISA kit detects both IgM and IgA antibodies (Photo courtesy of EUROIMMUN).

ELISA kit Offers Enhanced Diagnosis of Zika Virus Infection

An ELISA kit that measures anti-Zika virus antibodies of both the IgM and IgA classes was shown to accurately diagnose the acute phase of the infection even in patients with prior flavivirus exposure. More...
27 Aug 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.