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Recent News Expo Medica 2025 Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Molecular Diagnostics

Image: The MinION is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Oxford Nanopore Technologies).

Residual Disease in Leukemia Patients Identified by ddPCR

Currently, minimal residual disease for chronic myeloid leukemia (CML) patients is typically monitored using real-time quantitative polymerase chain reaction (RT-qPCR), but often leukemic stem cells with the BCR-ABL1 rearrangement are present below the limit of detect of RT-qPCR. More...
08 Feb 2018
Image: Histopathology of Endometriosis of the Fallopian Tube (Luminal Pattern). In this pattern, the normal complex, folded tubal mucosa is replaced by flat columnar epithelium with a tin underpinning of specialized endometrial stroma. There are also blood cells in the lumen Photo courtesy of Dr. Ed Uthman).

Genetic Biomarkers Determine Risk of Developing Endometriosis

Endometriosis is one of the most common women's health disorders, causing up to 10% of reproductive-age women to experience painful periods and potential infertility. Diagnosis can elude patients for decades, in part because exploratory surgery is considered the ultimate diagnostic method. More...
07 Feb 2018
Image: (A) Histology of a case of olfactory neuroblastoma with upregulation of CD24 gene by microarray, (B) confirmed by CD24 protein overexpression in the tumor cells (Photo courtesy of Caris Life Sciences).

Analysis Offers Treatment Options for Olfactory Neuroblastoma

Olfactory neuroblastoma (ONB) is a rare, locally aggressive, malignant neoplasm originating in the olfactory epithelium in the nasal vault. The recurrence rate of ONB remains high and there are no specific treatment guidelines for recurrent/metastatic ONBs. More...
01 Feb 2018
Image: Histopathology: (D) H&E staining showing the trabecular pattern of MAFA mutation-positive insulinomas. (E) Immunostaining shows diffuse MAFA expression in the tumor, at lower levels compared with the neighboring normal islets strongly expressing MAFA (Inset) (Photo courtesy of the Queen Mary University of London).

Mutation Found in Families with Contradictory Blood Sugars

Insulinomatosis is a condition characterized by the occurrence of multicentric insulinomas, pancreatic neuroendocrine tumors with β-cell–like features causing hyperinsulinemic hypoglycemia. More...
01 Feb 2018
Image: The BD FACS CANTO II multiparameter flow cytometer (Photo courtesy of BD Biosciences).

Genetic Mutation Linked to Crohn's and Parkinson's Diseases

The inflammatory bowel diseases (IBD) are composed of two major subtypes, Crohn’s disease (CD) and ulcerative colitis (UC), which are distinguished by the distribution of chronic inflammatory changes. More...
31 Jan 2018
Image: The diagnostic accuracy of the HostDx Sepsis assay compared to other methods (Photo courtesy of Inflammatix).

Immune Response Tests Enable Rapid Antibiotic Decisions

A novel test uses quantitative multiplex gene expression to analyze a patient's immune system, or the host response, rather than looking for the presence of a pathogen that indicates whether there is an infection in the blood. More...
31 Jan 2018
Image: The FDA-approved BRACAnalysis CDx test as a companion diagnostic (Photo courtesy of Myriad Genetics).

Lab-Developed Tests Compared with Approved Diagnostics

The debate about the role of the government-approved diagnostics in the regulation of laboratory-developed tests (LDTs) has focused attention on the analytical performance of all clinical laboratory testing. More...
30 Jan 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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