Molecular Diagnostics
Study Shows Labs Should Specify HPV Assay Used
Human papillomavirus (HPV) is a double-stranded DNA virus that infects squamous and glandular epithelial cells in the ectocervix and endocervix and integrates its genome into the host DNA, causing either an active or a latent infection without detectable symptoms. More...24 May 2018
Genome Sequencing Increases Sensitivity of Carrier Screens
Traditionally, carrier screening has focused on specific disorders that are known to have a higher prevalence in certain ethnic populations. More recently, lower sequencing costs coupled with higher accuracy of next generation sequencing-based methodologies have made it affordable for clinical laboratories to offer screening for substantially more conditions. More...23 May 2018
Hereditary Breast Cancer Tests Double Detection Rate
Germline genetic testing in patients newly diagnosed with cancer has the potential to reduce disease burden through secondary prevention and targeted therapies. There is a prerequisite to understand how genetic testing is being integrated into practice for patients newly diagnosed with cancer and the impact of results on treatment decisions. More...23 May 2018
Genetic Variations Increase Heart Attack Risk for Statin Patients
Coronary heart disease (CHD) is a leading cause of death globally. Although therapy with HMG-CoA reductase inhibitors (statins) decreases circulating levels of low-density lipoprotein cholesterol (LDL-C) and the incidence of CHD, additional events occur despite statin therapy in some individuals. More...22 May 2018
Genetic Predisposition Validated in Medulloblastoma
Medulloblastoma is a rare malignant tumor of the brain and occurs predominantly in children and is associated with rare hereditary cancer predisposition syndromes. It is believed that in many cases hereditary gene defects trigger the development of this malignant disease. More...22 May 2018
Specific Biomarker Discovered for Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disorder that occurs when the immune system mistakenly attacks the body's tissues. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of the joints, causing painful swelling that can eventually result in bone erosion and joint deformity. More...22 May 2018
Tool Predicts Deadly Form of Mycosis Fungoides
Mycosis fungoides (MF), the most common cutaneous T cell lymphoma (CTCL) is a malignancy of skin-tropic memory T cells. Most MF cases present as early stage (stage I A/B, limited to the skin), and these patients typically have a chronic, indolent clinical course. More...21 May 2018
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In Other News
Factors Affecting Plasma DNA Analysis Evaluated
Near-Patient Hepatitis C Assay Validated
Molecular Subtype Identified for CRCs Metastasized to Liver
Familial Genetics Influence Migraine Type
Kidney Disease Patient Urine Contains Diverse Bacteria
Genetic Scores Stratify Risk of Developing Type 1 Diabetes
Assays Using ddPCR Quantify DNA Fragments
EBV Protein Implicated in Autoimmune Diseases
Molecular Tests Equivalent to Bone Marrow Analysis for MM
Thyroid Cancer Genetics Study Finds New Mutations
Diagnostic SHERLOCK Optimized for Rapid Viral Detection
Streamlined Approach Discovered for Treating Bowel Cancer
Metagenomic Sequencing Can Diagnose Cases of Meningitis
Clostridium difficile Examined by Different Methods
Treponemal Subspecies Discriminated by LAMP
Molecular Technology Identifies Potential Biomarker for Cancer
Assay Detects Hepatitis B in Multiple Specimens
Genetic Variant Identified As Better Marker for CV Disease
CSF Examined for Enteroviral Nervous System Infection
Blood Test Predicts Onset of TB in Advance
Genetic Link to IBS Identified in Women
Genetic Test May Improve Post-Stent Treatment Outcome
Amino Acids Can Predict CV Disease Risk in Women
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.