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Recent News Expo ADLM 2025 Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Molecular Diagnostics

Image: Myoblast fusion. This graphic depicts normal myoblast (early muscle cells with a single nucleus) fusing together to form myocytes (multinucleated muscle cells) during myogenesis. In Carey-Fineman-Ziter syndrome this cascade is disrupted because of a defect in the membrane protein myomaker (MYMK) required for cell-cell fusion (Photo courtesy of Darryl Leja, NHGRI).

Genetic Mutations Causing CFZ Syndrome Identified

Researchers have identified gene mutations that cause, via a defect in myoblasts fusion, the rare inherited muscle disorder Carey-Fineman-Ziter Syndrome (CFZS), and have thereby also uncovered a mechanism underlying muscle development. More...
18 Jul 2017
Image: A space-filling model of substance P (Photo courtesy of Wikimedia Commons).

Tear Substance Indicates Possible Nerve Damage in Diabetes Patients

Measurement of levels of substance P peptide in tears has been proposed as a method for determining possible nerve damage in individuals suffering from diabetes. More...
17 Jul 2017
DIASOURCE (A Biovendor Company)
Image: A histopathology of urothelial carcinoma of the urinary bladder (Photo courtesy of Wikimedia Commons).

Urine Test Predicts Bladder Cancer Recurrence

A test that detects a specific enzyme in the urine is able to predict the likelihood of recurrence of disease in patients that have been treated for bladder cancer. More...
17 Jul 2017
Image: A light microscopy of an egg of Amphimerus sp. observed in a fecal specimen from Ecuador, almost indistinguishable from some other liver fluke eggs (Photo courtesy of Universidad Central del Ecuador).

Assay Detects Fish Trematode DNA in Human Stools

Amphimeriasis is a fish-borne disease caused by the liver fluke Amphimerus spp. that has recently been reported as endemic in the tropical Pacific side of Ecuador with a high prevalence in humans and domestic animals. More...
13 Jul 2017
Image: The dipstick device, a single-component, customizable, inexpensive biosensor uses live cells to detect pathogens worldwide (Photo courtesy of Columbia University).

Yeast-Based Tool Developed for Pathogen Detection

The monitoring of global pathogen burden has been traditionally limited to a small number of specialized centers, but more effective detection could be performed in real time by making accurate diagnostics accessible at the point of care. More...
13 Jul 2017
Image: A new study shows that so-called “liquid biopsies” - blood tests that detect circulating tumor DNA (ctDNA) - may not only sound an early alert that a treatment’s effect is diminishing, but may also help explain why and sometimes offer clues about what to do next (Photo courtesy of Massachusetts General Hospital).

Liquid Biopsy Blood Tests Detect CtDNA

The so-called “liquid biopsies” blood tests that detect circulating tumor DNA (ctDNA), may not only sound an early alert that a treatment’s effect is diminishing, but may also help explain why, and sometimes offering clues about what to do next. More...
12 Jul 2017
Image: This light microscope image shows the gut tissue of a child with CHAPLE disease. The large white areas in the bottom right corner are enlarged lymphatic vessels, which can contribute to intestinal distress (Photo courtesy of the US National Institute of Allergy and Infectious Diseases).

Gene Mutation Causes Rare Immune Disorder

A genetic cause and potential treatment strategy for a rare immune disorder called CHAPLE disease has been discovered and children with the condition can experience severe gastrointestinal distress and deep vein blood clots. More...
12 Jul 2017
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