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Molecular Diagnostics

Image: The HiSeq 4000 Systems provide a multi-application solution for production-scale genomic laboratories (Photo courtesy of Illumina).

Unexplained Illness Puts Pathogen Discovery to Test

High-throughput sequencing can provide insights into epidemiology and medicine through comprehensive surveys of viral genetic sequences in environmental and clinical samples. More...
05 Sep 2018
Image: Bone marrow aspirate from a patient with diffuse large B cell lymphoma (Photo courtesy of Peter Maslak).

Blood Test Predicts Lymphoma Therapy Success

A blood test can predict which patients with a type of cancer called diffuse large B cell lymphoma are likely to respond positively to initial therapy and which are likely to need more aggressive treatment. More...
04 Sep 2018
Image: Diagram of the Seq-Well low-cost platform for single-cell RNA sequencing (Photo courtesy of Shalek Lab).

Analysis of Nasal Polyps Suggests Mechanisms of Inflammation

Allergic inflammation can develop from persistent activation of type 2 immunity in the upper airway, resulting in chronic rhinosinusitis, which ranges in severity from rhinitis to severe nasal polyps. More...
04 Sep 2018
Image: A micrograph showing granulomatous inflammation of bladder neck tissue due to Bacillus Calmette-Guérin (BCG) used to treat bladder cancer (Photo courtesy of Wikimedia Commons).

New Test Predicts Potential Success of BCG Immunotherapy for Bladder Cancer

A laboratory test that measures the amount of IL2 secretion from CD4+ T cells after overnight in vitro incubation with tuberculin predicts the potential success of BCG (Bacille Calmette-Guérin) immunotherapy treatment for bladder cancer. More...
03 Sep 2018
Image: An illustration depicting a deep vein thrombosis (Photo courtesy of Wikimedia Commons).

Rapid Method Suggested for Diagnosis of DVT

A simple blood test has been proposed as an alternative to the fairly costly and time intensive ultrasound procedure for diagnosis of deep vein thrombosis (DVT). More...
03 Sep 2018
Image: Multiple myeloma, a cancer of the blood plasma (Photo courtesy of Medical News Today).

Multi-Omics Approach Guides Relapsed Multiple Myeloma Treatment

Many patients with relapsed multiple myeloma are not often matched with correct treatment options in a timely or personalized manner, and most patients have a median survival rate of six years. With standard diagnosis and treatment, relapses are usually inevitable and fatal for most patients. More...
30 Aug 2018
Image: The HiSeq X Five System enables ultra-high-throughput whole-genome sequencing at a cost and scale appropriate for large genome centers (Photo courtesy of Illumina).

Whole-Genome Sequencing Diagnoses Early Infantile Epileptic Encephalopathy

Early infantile epileptic encephalopathy (EIEE) is a rare epilepsy syndrome that causes intractable seizures with multiple seizure types and presents in the first months of life. While the prevalence of EIEE is unclear, and only affects a subset of all infants with seizures, infants with EIEE have serious medical complications. More...
30 Aug 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.