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Molecular Diagnostics

Image: Diagrams for X-linked inheritance when cancer status is specific to women (all carrier men are effectively disease censored). Two family patterns with a pair of first-degree affected women are the maternal grandmother (MGM) family and the paternal grandmother (PGM) family (Photo courtesy of Roswell Park Cancer Institute).

Ovarian Cancer Risk May Be Paternally Inherited

A history of ovarian cancer among first-order relatives remains the strongest and best-characterized predictor of ovarian cancer risk and a main determinant of genetic testing referral. More...
01 Mar 2018

Kidney Biopsy Profiles Predict Delayed Graft Function

The probability of renal graft failure can be assessed for donor kidney biopsies through histological analyses; the potential for delayed graft function is not as easily determined by morphology alone, but could potentially be aided by molecular analysis. More...
28 Feb 2018

Image: Principle scheme of antibody detection by ADAP for HIV (Photo courtesy of Stanford University).

Novel Saliva-Based PCR Assay Detects HIV Antibodies Earlier

An oral fluid-based test for human immunodeficiency virus (HIV) shows promise as a population-based screening tool. According to its developers, the test is easier to collect than blood but yields results that are just as reliable. More...
28 Feb 2018

$Image: Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized (Photo courtesy of Wikimedia Commons).$

Tests Links Circulating Tumor DNA and Breast Cancer Survival

Cancer researchers used a liquid biopsy test for circulating tumor DNA (ctDNA) to profile cancer genomes from blood samples and predict survival outcomes for patients with metastatic triple negative breast cancer. More...
27 Feb 2018

Image: A newly developed blood test detects pathogens carried by ticks such as this hard-bodied tick of the family Ixodidae (Photo courtesy of the CDC).

Blood Test Designed for Multiple Tick-borne Diseases

A novel blood test for the simultaneous diagnosis of multiple tick-borne diseases has been developed and shown to discriminate antibody responses to eight major tick-borne pathogens present in the United States. More...
27 Feb 2018

Image: A bone marrow biopsy showing plasma cells from a patient with multiple myeloma (Photo courtesy of the American Society of Clinical Oncology).

Multiple Myeloma Risk Genes Revealed

Two genes have been uncovered with apparent ties to inherited multiple myeloma risk, starting from analyses of several large American families that are frequently affected by the complex blood plasma cell cancer. More...
23 Feb 2018

Image: The Agilent 2100 bioanalyzer is a distinctive analysis tool capable of handling cells, proteins and nucleic acids on a single platform (Photo courtesy of Agilent Technologies).

Next-Gen Sequencing of CSF Diagnoses Neurobrucellosis

Brucellosis is the most common zoonotic infection in the world with more than 500,000 new cases are reported annually worldwide. It is a multisystem infection, with variable clinical presentations and brucellosis with nervous system involvement is known as Neurobrucellosis (NB). More...
21 Feb 2018

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.