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Molecular Diagnostics

Image: The HTG EdgeSeq processor, assays, and parser software facilitate analysis of gene expression profiles from a wide variety of specimen types (Photo courtesy of HTG Molecular Diagnostics).

CSF MicroRNA Levels Investigated for Prodromal HD

Huntington disease (HD) is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition). Adult-onset HD is the most common form of this disorder and the mean age of onset of HD is 35 to 44 years and the median survival time is 15 to 18 years after onset. More...
17 Jan 2018

Genetic Study Predicts Stomach Cancer Progression

Although stomach cancer is treatable if detected early, diagnosis often occurs at an advanced stage, resulting in high mortality. Intestinal metaplasia (IM) is a pre-malignant condition of the gastric mucosa associated with increased gastric cancer (GC) risk. More...
17 Jan 2018
Image: Researchers have identified genes that could be precursors to Alzheimer’s disease, which could be targets for new treatments that may delay or prevent the onset of the disease (Photo courtesy of Medical News Today).

Genetic Factors Responsible for Alzheimer's Disease Identified

Several new genes have been identified that are responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins in cerebrospinal fluid (CSF). More...
16 Jan 2018
Image: Acute lymphoblastic leukemia (Photo courtesy of Pathology Outlines).

Tumor Suppressor Gene Variants Identified for Leukemia Patients

Newly identified germline variations in a key tumor suppressor gene predispose individuals to develop leukemia as children and leave them with a 1-in-4 chance of developing a second cancer later. Acute lymphoblastic leukemia is the most common childhood cancer and in most cases, the exact cause is unknown. More...
16 Jan 2018
Image: A three-dimensional (3D) structure of caffeine (Photo courtesy of Wikimedia Commons).

Caffeine Levels Prove Diagnostic for Early Parkinson's Disease

A team of Japanese researchers demonstrated that serum caffeine and its metabolites were reliable biomarkers for detection of early Parkinson's disease (PD). More...
15 Jan 2018
Image: Peripheral blood film from a newborn with hydrops fetalis; note the hypochromia, anisopoikilocytic changes, and erythroblastosis (Photo courtesy of Boston Medical Center).

Parental Screening Can Prevent Hydrops Fetalis in Fetus

Hydrops fetalis (fetal hydrops) is a serious fetal condition defined as abnormal accumulation of fluid in two or more fetal compartments, including ascites, pleural effusion, pericardial effusion, and skin edema. More...
10 Jan 2018
Image: The Sensititre OptiRead automated fluorometric plate reading system for use with Sensititre microtiter plates in antibiotic susceptibility tests (Photo courtesy of Thermo Fisher Scientific).

Mycobacterium Mutations Associated with Clarithromycin Resistance

Mycobacterium abscessus is a leading cause of respiratory diseases and soft tissue infections and it is naturally resistant to many antibiotics in vitro, which complicates clinical treatment and leads to unsatisfactory results. More...
09 Jan 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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