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Molecular Diagnostics

Image: The RainDrop droplet digital polymerase chain reaction system (ddPCR) (Photo courtesy of RainDance Technologies).

Non‐Invasive Prenatal Diagnosis of Spinal Muscular Atrophy Validated

The discovery of cell‐free DNA (cfDNA) in maternal plasma has enhanced the development of non‐invasive prenatal testing (NIPT). More...
08 Oct 2019
Image: A typical mitochondrial network (green) in two human cells (Photo courtesy of Wikimedia Commons).

Mitochondrial Clearance Failure Provides Diagnostic Marker for Parkinson's Disease

Failure of mitochondria to remove the Miro1 protein following depolarization provides a biomarker that can be used for diagnosis of Parkinson's disease. More...
07 Oct 2019
Image: Scanning electron micrograph of a pair of Schistosoma mansoni (Photo courtesy of the Davies Laboratory Uniformed Services University).

RT-PCR Evaluated for Diagnosis of Imported Schistosomiasis

Schistosomiasis is one of the most important human parasitic neglected tropical diseases. It is a major source of morbidity and mortality in Africa but also in South America, the Caribbean, the Middle East, and Asia. More...
03 Oct 2019
Image: The ImageQuant LAS 4000 biomolecular imager (Photo courtesy of GE Healthcare).

Breakthrough Kit May Enable Early Alzheimer's Diagnosis

Alzheimer’s disease (AD) is a neurodegenerative disease with the highest incidence and is one of the most common central neurological disorders. According to the World Health Organization (WHO), in 2016, the global number of individuals who lived with dementia was 43.8 million. More...
02 Oct 2019
Image: Color-enhanced scanning electron micrograph showing Salmonella typhimurium (red) invading cultured human cells (Photo courtesy of US National Institute of Allergy and Infectious Diseases).

Drug-Resistant Strains of Salmonella Causing Bloodstream Infections

Salmonella enterica subspecies enterica serovar Typhimurium (known as S. typhimurium) and other non-typhoidal Salmonella are common causes of gastrointestinal infections in people living in industrialized countries. More...
02 Oct 2019
Image: The use of RNA-seq as a decentralized methodology at the core of the MammaPrint and BluePrint microarray-based diagnostic technology (Photo courtesy of Agendia).

Targeted RNA Sequencing Technology Diagnoses Breast Cancer

In recent years, RNA-sequencing (RNA-seq) technology has become the standard for transcriptome analysis because of its flexibility, sensitivity, and accuracy in measuring gene expression. RNA-seq is a technology in which cDNA is derived from RNA, followed by library construction and massively parallel deep sequencing. More...
01 Oct 2019

New Guidelines Designed to Help Diagnose Chronic Diarrhea

A newly published official guideline for diagnosing chronic watery diarrhea was established to aid clinicians in choosing appropriate laboratory tests to exclude other diagnoses in the setting of suspected functional diarrhea or diarrhea-predominant irritable bowel syndrome (IBS-D). More...
30 Sep 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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