Molecular Diagnostics
Tumor Mutational Load Predicts Survival Post-Immunotherapy
A survey of thousands of advanced cancers suggests a way to identify those most likely to respond to groundbreaking therapies that unleash an immune response against tumors, but the results highlight how difficult it will be to translate such an approach into a reliable clinical test. More...31 Jan 2019
DNA Extraction Technique Improved for Chagas Diagnosis
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is endemic in many parts of the Americas, where six to seven million people are infected. In the acute phase of the infection, serology may still be negative but positive for parasite by microscopic examination or by culture in specialized medium. More...28 Jan 2019
Molecular Prognostic Biomarker Found for CNS Lymphoma
Primary central nervous system lymphoma (PCNSL), a rare subgroup of diffuse large B-cell lymphoma (DLBCL) arising in the central nervous system (CNS), is an aggressive malignant variant of nodal non-Hodgkin lymphoma (NHL). PCNSLs account for 3% of all primary CNS tumors and 1% of NHLs in adults. More...24 Jan 2019
Gene-Based Risk Scores Predicts Alcoholic Cirrhosis
Alcoholic chronic liver disease, with a prevalence of around 12% in the European and North-American populations, is characterized by a broad spectrum of conditions ranging from simple steatosis to alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. More...23 Jan 2019
Prognostic Signature Described in HPV-Positive Cell Carcinomas
Human papilloma virus (HPV) is an etiological agent of oropharyngeal squamous cell carcinoma (OPSCC). Patients with HPV+ OPSCC have high long-term survival rates: however, current radiation protocols are aggressive and can result in life-long morbidities, including difficulty swallowing, chronic dry-mouth, and altered speech. More...23 Jan 2019
Genetic Methods Rapidly Diagnoses Huntington's Disease
People with Huntington's disease suffer from jerky body movements and decreasing mental abilities. The condition usually leads to death 15 to 20 years after diagnosis. The cause of the disease is a region in the Huntingtin gene (HTT) that is absent in healthy people. More...23 Jan 2019
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In Other News
Urinary Detection Method Developed for Prostate Cancer
Latinos and Hispanics Prone to Kidney Disease Gene Variant
Age-Related Remodeling Linked to Normal Aging
Tumor Sequencing Finds Mutations Caused by Blood Disorder
Newborn Genomic Sequencing Detects Disease Risk Factors
Tools for Meningitis Diagnostics Implemented in Resource-Limited Settings
LAMP Test Rapidly Detects Sexually Transmitted Chlamydia
New Risk Loci Identified for Polycystic Ovary Syndrome
Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing
Rapid Next-Gen Sequencing Method Predicts Prostate Cancer Risks
Metastatic Colorectal Cancer Linked to Transcription Factors
Epigenetic Cervical Cancer Test Has Perfect Detection Rate
Molecular Cause Found for Rare Autoimmune Disorders
Gut Microbes Differ Between Two Common Conditions
Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing
Neuroblastoma Molecular Analysis Leads to Prognostic Markers
Genetic and Epigenetic Features Found in Glioma Tumors
Tick-Borne Diseases Diagnosed with Multiplex Molecular Panel
HCV-RNA Present in Body Fluids in High Viral Load Patients
Banna Virus Detected by Reverse Transcription-Loop-Mediated Isothermal Amplification
Alzheimer's Disease Risk Alleles Profiled in Latino Populations
Genetic Marker Predicts Early Relapse in Pediatric ALL
Colorectal Cancer Risk Linked to Common and Rare Variants
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
