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Molecular Diagnostics

Image: The structure of the annexin 5A protein (Photo courtesy of Wikimedia Commons).

Novel Fluorescent Technique Detects Early Stage Glaucoma

A team of British glaucoma researchers used a novel fluorescent microscopy technique to rapidly diagnose the disease at a very early stage. More...
08 May 2017
Image: A histologic view of an endometrial adenocarcinoma showing many abnormal nuclei (Photo courtesy of Wikimedia Commons).

Low Levels of 1-Asparaginase Predict Cancer Recurrence

Loss of expression of the enzyme ASRGL1 (l-asparaginase) was shown to be an independent biomarker for disease-specific survival in uterine cancer (endometrioid endometrial carcinoma). More...
08 May 2017
Image: A histopathology of breast cancer:  intraductal carcinoma, noncomedo type, distended duct with intact basement membrane, micropapillary, and early cribriform growth pattern membrane and central tumor necrosis (Photo courtesy of Dr. Peter Abdelmessieh).

Multigene Test Extends Life Expectancy for Cancer Patients

Testing for variants in seven cancer-associated genes, versus the usual process of testing in just two genes, followed by risk-reduction management could cost-effectively improve life expectancy for women at risk of hereditary breast cancer. More...
04 May 2017
Image: The Great Basin bench top analyzer with assay cartridge (Photo courtesy of Great Basin Scientific).

Bordetella Direct Test Receives FDA Clearance

It is estimated that there are approximately 16 million cases of pertussis per year globally, with the disease being responsible for 195,000 deaths annually and reported cases of pertussis, known vernacularly as whooping cough, in the USA have spiked since 1955. More...
04 May 2017
Image: The card used for the detection of Methicillin-resistant Staphylococcus aureus (MRSA) (Photo courtesy Great Basin Scientific).

Bacterial Pathogens Panel Receives CE Marking

A Stool Bacterial Pathogens Panel is designed to simultaneously detect Salmonella species, Shigella species, Shiga Toxin-producing E. coli (stx1, stx 2, O157 serotype-specific genes), and Campylobacter species (C. jejuni and C. coli), all significant bacterial pathogens. More...
04 May 2017
Image: The ABI 7500 Fast Dx real-time PCR instrument (Photo courtesy of Applied Biosystems).

Methods Assessed for Detecting Asymptomatic Malaria

Asymptomatic malaria infection refers to malarial parasitemia of any density in the absence of fever or other acute symptoms in individuals who have not received recent antimalarial treatments. More...
03 May 2017
Image: A histopathology of Cytomegalovirus (CMV) Placentitis (Photo courtesy of Dr. Ed Uthman).

Newborn Screening for CMV Remains Controversial

Cytomegalovirus (CMV) is the most common infectious cause of congenital sensorineural hearing loss, which leads to speech and language delay and the virus also causes microcephaly, developmental disability, and vision abnormalities. More...
03 May 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.