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Molecular Diagnostics

Image: The cBot 2 System streamlines the sequencing workflow by automating cluster generation. It was a required accessory instrument for HiSeq sequencers (Photo courtesy of Illumina).

Sequencing Study Links DNA Alterations to Type 2 Diabetes

According to statistics from the World Health Organization, over 400 million people worldwide have diabetes. The vast majority of these cases are type 2 and diabetes is estimated to be the seventh leading cause of death globally. More...
06 Jun 2019

FDA Clears CT/NG Assays for Extragenital Testing

Chlamydia trachomatis commonly known as chlamydia is a bacterium that can replicate only in human cells. It can manifest in various ways, including: trachoma, lymphogranuloma venereum, non-gonococcal urethritis, cervicitis, salpingitis, pelvic inflammatory disease. More...
05 Jun 2019

Image: A diagram of genomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes (Photo courtesy of Peking University).

Genomic Analysis Uncovers Differences in Liver Cancer Subtypes

Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy arising from the liver. ICC makes up about 10% of all cholangiocarcinomas. It arises from the peripheral bile ducts within the liver parenchyma, proximal to the secondary biliary radicals. More...
05 Jun 2019

Image: The Abi Prism 7900 HT sequence detection system (Photo courtesy of Applied Biosystems).

Oral Bacteria Found in Cerebral Emboli of Stroke Patients

In addition to traditional causative factors, such as hypertension, hypercholesterolemia, diabetes mellitus, smoking, and obesity, bacterial inflammation has been suggested to contribute directly or indirectly to the development of the atherosclerosis and atherothrombotic events. More...
05 Jun 2019

Image: A histopathology of colorectal carcinoma: an example of moderately differentiated adenocarcinoma showing complicated glandular structures in a desmoplastic stroma (Photo courtesy of the David Geffen School of Medicine at the University of California).

CtDNA Forecasts Non-Metastatic Colorectal Cancer Recurrence

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. More...
29 May 2019

Stem Cell Transplantation Increases Risk of Infection-Related Mortality

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapeutic modality for various malignant and nonmalignant hematological conditions. The best results of allogeneic HSCT were obtained when the stem cells from a human leukocyte antigen (HLA)-matched sibling were used, such a donor can only be found for approximately 30% of patients. More...
29 May 2019

Stem Cell Transplantation Increases Risk of Infection-Related Mortality

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapeutic modality for various malignant and nonmalignant hematological conditions. The best results of allogeneic HSCT were obtained when the stem cells from a human leukocyte antigen (HLA)-matched sibling were used, such a donor can only be found for approximately 30% of patients. More...
29 May 2019

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.