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Molecular Diagnostics

Image: High magnification micrograph of a meningioma showing the characteristic whirling (Photo courtesy of Wikimedia Commons)

Newly Identified Biomarker Distinguishes Potentially Aggressive Meningiomas

 Identification of a novel biomarker will allow clinicians to differentiate between truly benign meningiomas and those that will eventually progress, grow rapidly, and spread. More...
13 Nov 2019
Image: Simultaneous detection of Anaplasma spp., Bartonella spp., Borrelia spp., Coxiella burnetii, Francisella spp., and Rickettsia spp. on a tick-borne bacteria flow chip (TBFC) kit (Photo courtesy of Rutgers University).

Rapid DNA Flow Technology Platform Detects Tick-Borne Bacterial Pathogens

 Ticks are the most important vectors for infectious diseases in the northern hemisphere and second only after mosquitos worldwide. As a result, there is an increasing public health interest in tick-borne pathogens. More...
13 Nov 2019
Image: Serum flotillin levels in patients with AD were lower than those in non-AD cases (Photo courtesy of Makoto Michikawa, Nagoya City University)

Researchers Recommend the Membrane Protein Flotillin as a Biomarker for Alzheimer’s Disease

A team of Japanese researchers have suggested adding the protein flotillin to the arsenal of biomarkers that can be used to diagnose Alzheimer’s disease. More...
12 Nov 2019
Image: The hand-held Genie III scanner has a two-color fluorescence excitation and detection system (Photo courtesy of OPTIGENE Ltd).

Inexpensive LAMP-Based Schistosomiasis Tests Developed

Schistosomiasis is one of the most prevalent Neglected Tropical Diseases, affecting approximately 250 million people worldwide. Schistosoma mansoni is the most important species causing human intestinal schistosomiasis. More...
12 Nov 2019
Image: Translocation: a fragment of a chromosome is moved (trans-located) from one chromosome to another and joins a non-homologous chromosome. The balance of genes is still normal (nothing has been gained or lost), but can alter phenotype as it places genes in a new environment (Photo courtesy of Indiana University).

Chromosomal Abnormalities Associated with Recurrent Miscarriage

Recurrent miscarriage, or the loss of two or more pregnancies, affects between 1% and 2% of couples. Chromosomal abnormalities are the major genetic cause of miscarriage and are detected by routine analysis in about 1 in 50 couples. More...
11 Nov 2019
Image: A liquid biopsy blood test that measures the amount of cell-free DNA (cfDNA) in the bloodstream correlates with how patients will progress after they are diagnosed with glioblastoma (Photo courtesy of University of Pennsylvania School of Medicine).

Use of Cell-free DNA Liquid Biopsy to Predict Glioblastoma Progression

Cancer researchers have demonstrated the potential clinical utility of liquid biopsy to measure plasma cell-free DNA (cfDNA) in patients with newly diagnosed glioblastoma in order to predict the progression of the disease. More...
11 Nov 2019
Image: A scanning electron micrograph (SEM) of prostate cancer cells (Photo courtesy of Sloan Kettering Institute).

Prostate Cancer Methylation Levels Linked to Epigenetic Profiles

Prostate cancer is cancer that occurs in the prostate, a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm. Prostate cancer is one of the most common types of cancer in men. More...
07 Nov 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.