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Molecular Diagnostics

Image: Genome-wide human SNP array 6.0 GeneChip (Photo courtesy of Affymetrix).

Metastatic Colorectal Cancer Linked to Transcription Factors

Colorectal cancer (CRC) is a kind of malignant human tumor with high mortality around the world. The incidence of colorectal cancer shows a gender difference and is prone to the elderly. More...
03 Jan 2019
Image: A new screening method for cervical cancer has proven 100% accurate in testing (Photo courtesy of Health News).

Epigenetic Cervical Cancer Test Has Perfect Detection Rate

Human papillomavirus (HPV) ‐based cervical cancer screening requires triage of HPV positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or worse. More...
02 Jan 2019
Image: The Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer (Photo courtesy of Thermo Fisher Scientific).

Molecular Cause Found for Rare Autoimmune Disorders

It is estimated that more than 20 million Americans suffer from autoimmune disorders. They include rheumatoid arthritis, psoriasis, inflammatory bowel disease, multiple sclerosis, lupus, type 1 diabetes, and dozens of others. More...
01 Jan 2019
Image: A colored scanning electron micrograph (SEM) of Faecalibacterium prausnitzii, one of the most abundant anaerobic bacteria in the human gut microbiota, and its relative abundance is a biomarker of intestinal health in adults (Photo courtesy of BioFoundations).

Gut Microbes Differ Between Two Common Conditions

Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are two of the most common diseases of the gastrointestinal tract. Unlike IBD, IBS does not cause inflammation, ulcers or other damage to the bowel. More...
01 Jan 2019
Image: The Oncomine Focus Assay is performed using the Ion Torrent technology. The test is designed to help oncologists expedite selection of a treatment plan for their patients in days instead of weeks (Photo courtesy of Thermo Fisher Scientific).

Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing

Guidelines are rapidly moving toward upfront profiling with next-generation sequencing (NGS) of all advanced lung cancers, but there are still practical issues with this testing method that can limit clinical testing and prevent or delay patients being started on targeted therapies. More...
31 Dec 2018
Image: Histopathology of a typical neuroblastoma with rosette formation (Photo courtesy of Dr. Mark Applebaum, MD).

Neuroblastoma Molecular Analysis Leads to Prognostic Markers

Neuroblastoma is a pediatric tumor of the sympathetic nervous system. Its clinical course ranges from spontaneous tumor regression to fatal progression. It most frequently starts from one of the adrenal glands, but can also develop in the neck, chest, abdomen, or spine. More...
27 Dec 2018
Image: SureSelect Target Enrichment Systems (Photo courtesy of Agilent Technologies).

Genetic and Epigenetic Features Found in Glioma Tumors

Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that is characterized by cutaneous findings, most notably café-au-lait spots and axillary freckling, by skeletal dysplasias, and by the growth of both benign and malignant nervous system tumors, most notably benign neurofibromas. More...
27 Dec 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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