Molecular Diagnostics

CD MicroRNA Marks Subtypes with Differing Outcomes
Crohn’s disease (CD), one of the primary inflammatory bowel diseases (IBD), is a chronic inflammatory condition of the gastrointestinal tract resulting from an aberrant immune response to the enteric microbiota in a genetically susceptible host. More...25 Oct 2018

Novel Technology Enables Detection of Early-Stage Cancer
Non-small-cell lung carcinoma (NSCLC) is often fatal because most cases are not diagnosed until they are so advanced that surgical intervention is no longer possible. To improve outcomes a blood test has been developed to detect lung cancer earlier in the disease. More...24 Oct 2018

Epigenomic Method Developed to Detect Pancreatic Cancer
Pancreatic cancers are typically diagnosed at late stage where disease prognosis is poor as exemplified by a 5-year survival rate of 8.2%. Earlier diagnosis would be beneficial by enabling surgical resection or earlier application of therapeutic regimens. More...24 Oct 2018

Multiple Myeloma Subtypes Linked to Patient Ancestry
Multiple myeloma (MM) is two- to three-fold more common in African Americans compared to European Americans. This striking disparity, one of the highest of any cancer, may be due to underlying genetic predisposition between these groups. More...23 Oct 2018

Test Identifies More Treatable Cancer Mutations Than Biopsies
Standard of care therapies that target specific mutations have changed the face of cancer treatment, and screening for such mutations, which can be drivers of both disease growth and treatment resistance. This can often be done with a biopsy of tumor tissue, but sometimes that tissue is hard to obtain or does not have sufficient DNA for analysis. More...22 Oct 2018


In Other News
Study Shows Zika Virus Persists in Body Fluids
Next-Gen Test Authorized for Minimal Residual Disease
Human Pegivirus Identified in Encephalitis Patients
Novel Fecal Biomarker Found for Colorectal Cancer
Individual HPV Types Linked to HIV Infection
Detection System Used for Monitoring Small Molecules
Antibiotic-Resistant Mutations Revealed by Sequencing Method
Disease-Associated Variants in Genes Allow Early Diagnosis
New Gene Variants Associated with Chronic Back Pain
TB Sequencing Could Replace Drug Susceptibility Testing
Cancer Liquid Biopsy Assay Detects Low-Level Mutations
Pneumonia Diagnosed by Nanopore Sequencing of Sputum
Nanopore Sequencing Enables Outbreak Field Surveillance
Dementia Assay Gets Favorable Evaluation
Disease Progression Apprised by Post-Treatment Mutation Sequencing
DNA Test Predicts Risk of Leukemia Relapse
MALDI-TOF MS Used to Identify Pythiosis
Determining Fibrosis Stage in Non-Alcoholic Fatty Liver Disease
Biomarkers Measured for Early Detection of Huntington's Disease
Targeted Sequencing Approach for Sarcoma Gene Fusions Validated
New mRNA Cancer Drivers Revealed in Chronic Lymphocytic Leukemia
Elevated Gene Expression Correlates with Prostate Cancer Severity
Breast and Ovarian Cancers Associated with Predisposition Genes
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.