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Molecular Diagnostics

Image: A diagram of the 20-Gene Set Predictive of Progression to Severe Dengue study (Photo courtesy of Stanford University School of Medicine).

Dengue Severity Predicted by Gene Expression Signature

About 400 million individuals annually are infected with any of the four dengue virus (DENV) serotypes and although the majority of symptomatic individuals present with acute dengue fever, a fraction, between ∼5% to 20% of these patients progress to severe dengue infection. More...
14 Feb 2019
Image: An Evalyn Brush used for patient self-sampling of the cervico-vaginal area (Photo courtesy of Rovers Medical Devices).

Accuracy of Self-Sampling for HPV Screening Evaluated

Molecular testing for human papillomavirus (HPV) using patient-collected cervico-vaginal samples has shown similar levels of accuracy to testing done on clinician-collected samples and could boost participation in overall HPV screening. More...
13 Feb 2019
DIASOURCE (A Biovendor Company)
Image: Microsporidian spores stained Calcofluor White M2R (Photo courtesy of Institute Pasteur of Tunis).

Symptomatic Respiratory Pathogen Found in Transplant Recipients

As opportunistic pathogens, microsporidia cause symptomatic infections mainly in patients with impaired immune function; and microsporidial dissemination to the central nervous system, eyes, and respiratory and urinary tracts has been documented in these patients. More...
13 Feb 2019
Image: Microsporidian spores stained Calcofluor White M2R (Photo courtesy of Institute Pasteur of Tunis).

Symptomatic Respiratory Pathogen Found in Transplant Recipients

As opportunistic pathogens, microsporidia cause symptomatic infections mainly in patients with impaired immune function; and microsporidial dissemination to the central nervous system, eyes, and respiratory and urinary tracts has been documented in these patients. More...
13 Feb 2019
Image: The Benchmark XT System, a fully automated staining system (Photo courtesy of Ventana Medical Systems).

Genetic Causes of Salivary Gland Carcinoma Discovered

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland. Until now, the molecular causes for the illness were unknown. More...
13 Feb 2019
Image: A diagram of whole-exome sequencing to identify genetic variants (Photo courtesy of NGXBIO).

Whole-Exome Sequencing Evaluates Fetal Structural Anomalies

In about 3% of pregnancies, ultrasound imaging will reveal a significant fetal physical anomaly and knowing the cause of the anomaly can help doctors and parents be better prepared, both during the pregnancy and after delivery. More...
12 Feb 2019
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Direct Blood PCR Detects Thromboembolism-Associated Mutations

Routine genetic testing is recommended in several clinical circumstances, particularly in patients with venous thrombosis at younger age, a strong family history of thrombotic disease, or in women with a history of venous thrombosis during pregnancy. More...
11 Feb 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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