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Molecular Diagnostics

Image: The Cyan ADP flow cytometer (Photo courtesy of Beckman Coulter).

Specific RUNX1 Mutations Cause Different Disease Types

Mutations of the hematopoietic master regulator RUNX1 are associated with acute myeloid leukemia, familial platelet disorder and other hematological malignancies whose phenotypes and prognoses depend upon the class of the RUNX1 mutation. More...
28 Jan 2021
Image: FIT (Fecal Immunochemical Test) is a stool test designed to identify possible signs of bowel disease. It detects minute amounts of blood in feces (fecal occult blood) (Photo courtesy of Alpha Laboratories, United Kingdom)

Study Confirms Performance of Rapid Stool Test for Detection of Colorectal Cancer

A recently published paper confirmed the diagnostic performance of the fecal immunochemical test (FIT) for patients with low-risk symptoms of colorectal cancer. More...
27 Jan 2021
Image: Diagram of asthma (Photo courtesy of Wikimedia Commons)

Monitoring of Urinary Eicosanoids Distinguishes Mild and Severe Asthma

A novel method for diagnosing severe asthma is based on the monitoring of eicosanoid compounds in samples of urine. More...
26 Jan 2021
Image: The Leica Bond III stainer is fully automated Immunohistochemical and In Situ Hybridization (IHC and ISH stainer) (Photo courtesy of Leica Biosystems).

Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens

DNA mismatch repair (MMR) status is routinely assessed in colorectal and endometrial carcinoma as a method of cancer prevention, surveillance in patients with Lynch syndrome and their families, and for prognostic, predictive, and therapeutic implications. More...
25 Jan 2021
Image: Blood smear from a P. falciparum culture: several red blood cells have ring stages inside them while close to the center is a schizont and on the left a trophozoite (Photo courtesy of Wikimedia Commons)

Panel of MicroRNAs Differentiates Uncomplicated and Severe Malaria in Children

MicroRNAs (miRNAs), which are rapidly released from damaged tissues into the host fluids, constitute a promising biomarker for the prognosis of severe malaria. More...
25 Jan 2021
Image: Photomicrograph of omental nodules indicated an adenocarcinoma infiltrating the adipose and fibrous tissues (Photo courtesy of Beijing Shijitan Hospital).

Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles

Peritoneal Carcinomatosis (PC) is a late stage manifestation of several gastrointestinal malignancies including appendiceal, colorectal, and gastric cancer. In PC, tumors metastasize to and deposit on the peritoneal surface and often leave patients with only palliative treatment options. More...
21 Jan 2021
Image: Histopathology of neurofibrillary tangles in the brain of a patient with Alzheimer`s disease (Bielschowski silver stain) (Photo courtesy of Dimitri P. Agamanolis, MD).

Alzheimer's Disease Subtypes Proposed from Brain Gene Expression Profiles

Alzheimer’s disease (AD) is the most common form of dementia in the elderly, estimated to affect more than 5.8 million individuals in the USA and more than 50 million worldwide, with almost half of individuals aged over 75 years. More...
18 Jan 2021
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New
Urine Analyzer
respons® UDS100


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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