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Molecular Diagnostics

Image: Li-Fraumeni Syndrome: a) High-grade invasive ductal carcinoma with p53 overexpression; b) mutant pattern in a patient with a germline TP53 missense mutation (Photo courtesy of Brigham and Women’s Hospital)

Liquid Biopsy Enables Early Cancer Detection in Li-Fraumeni Syndrome Patients

Patients with Li-Fraumeni Syndrome (LFS) harbor germline pathogenic variants in the TP53 gene causing predisposition to many cancers from childhood through late adulthood and can accelerate the onset of cancer by more than 30 years. More...
05 Apr 2022
Image: World-first bedside genetic test could prevent babies going deaf (Photo courtesy of The University of Manchester)

World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies

A new bedside machine takes just 25 minutes to identify whether a critically ill baby admitted to intensive care has a gene that could result in permanent hearing loss if they are treated with a common emergency antibiotic. More...
05 Apr 2022
Image: World-first bedside genetic test could prevent babies going deaf (Photo courtesy of The University of Manchester)

World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies

A new bedside machine takes just 25 minutes to identify whether a critically ill baby admitted to intensive care has a gene that could result in permanent hearing loss if they are treated with a common emergency antibiotic. More...
05 Apr 2022
Image: Proteins could one day allow breast cancer screening to be done with a blood test (Photo courtesy of Unsplash)

Blood Test to Detect Protein Biomarkers Identified Using Breast Milk Could Enable Breast Cancer Screening

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers identified by researchers using breast milk. The newly identified biomarkers are for a specific type of cancer called invasive ductal carcinoma (IDC), one of the most common types of breast cancers, but the approach could be used to identify biomarkers for other types of breast cancer as well. More...
05 Apr 2022
Image: Dementia, which can be caused by buildup of toxic molecules, cause brain injury, loss of memory and decline in intelligence (Photo courtesy of 123rf.com)

Newly Identified Biomarkers Detect Subcortical Small-vessel Disease

Biomarkers have been identified that were able to differentiate between classical Alzeheimer’s disease and subcortical small-vessel disease (SSVD), which is the most common vascular cognitive disorder. More...
04 Apr 2022
Image: Blood-based microRNA analysis could predict overall survival for advanced NSCLC (Photo courtesy of Unsplash)

miRNA-Based Blood Borne Diagnostic Test Holds Potential for Management of Cancer Patients

A first-of-its-kind microRNA (miRNA) biomarker signature offers the prospect of a blood-based companion diagnostic for immunotherapy in advanced non-small cell lung cancer (NSCLC). More...
01 Apr 2022
Image: Liquid biopsy opens up new possibilities for earlier diagnosis (Photo courtesy of University of Eastern Finland)

Liquid Biopsy Can Detect Recurrent Breast Cancer and Monitor Progression

A new study has found that liquid biopsy performed on serum samples taken from breast cancer patients can provide increasingly accurate information on cancer progression and enable earlier detection of cancer recurrence. More...
31 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.