Molecular Diagnostics

Streamlined Method for Telomere Length Measurement Opens New Cancer Diagnostic Opportunities
In a novel approach to cancer diagnosis, researchers have developed a high-throughput digital real-time PCR method for rapidly measuring the absolute lengths and quantities of individual telomere molecules. More...01 Sep 2020

Pan-Cancer Study Reveals Extrachromosomal DNA Frequency
Extrachromosomal circular DNA (eccDNA) are circular DNA found in human, plant and animal cells in addition to chromosomal DNA. eccDNA originate from chromosomal DNA and can be from 50 base pairs to several mega-base pairs in length and encode regulatory elements and several full genes. More...01 Sep 2020


New Pooling Strategy Increases Efficiency and Reduces Cost of COVID-19 PCR Tests
A new way of manipulating samples for COVID-19 testing of asymptomatic and symptomatic individuals provides both an eight-fold increase in testing efficiency, as well as an eight-fold reduction in test costs. More...31 Aug 2020

Loop-Mediated Isothermal Amplification-Assay Rapidly Diagnoses COVID-19
The SARS-CoV-2 (COVID-19) pandemic of 2020 has resulted in unparalleled requirements for RNA extraction kits and enzymes required for virus detection, leading to global shortages. This has necessitated the exploration of alternative diagnostic options to alleviate supply chain issues. More...25 Aug 2020

Newborn Exome Sequencing Locates Inborn Errors of Metabolism
Inborn errors of metabolism (IEM) form a large class of genetic diseases involving congenital disorders of metabolism. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substrates into others products. More...25 Aug 2020
In Other News
Gene Panel Predicts Likely Survival Time for Ovarian Cancer Patients
Single-Cell Analysis Provides New Insights into Mitochondrial Diseases
Isoform-Specific Loss Of Dystonin Causes Charcot-Marie-Tooth Disease
Blood Bank NAT-Based Assay Prevents Transfusion-Transmitted Malaria
Circulating tumor DNA Test Predicts Immunotherapy Response
Lab Profiles Differentiate MIS-C From Severe Pediatric COVID-19
Two Simple Methods Prepare DNA Suitable For Digital PCR
Elevated Glycolated Hemoglobin in Young People Predicts Likelihood of Diabetes or Cardiovascular Disease in Adulthood
Diagnostic Test Identifies Resistance Mutation that Enables Use of Inexpensive, Single Dose Gonorrhea Drug
Panel of Five Serum Biomarkers Identifies COVID-19 Patients at High Risk to Develop Serious Complications
Host Genetic, Environmental Factors Influence Urinary Tract Microbiome
Automated Malaria Diagnosis Enhanced by Deep Neural Networks
Phosphorylated-Tau Blood Test Identifies Asymptomatic Alzheimer’s Disease
Somatic Evolution Identified in Non-Neoplastic IBD-Affected Colon
Liquid Biopsy Test Accurately Detects Cancer in Nonsymptomatic Individuals
Elevated Angiotensin 1–7/Angiotensin II Ratio Predicts Favorable Outcomes in Patients with Heart Failure with Potential Link to COVID-19 Patients
Nanostar Biosensors Use Raman Scattering for Direct Detection of Cancer-Related MicroRNAs
Pediatric Ependymoma Single-Cell Analysis Signatures Linked to Outcomes
Combined Proteomic/Genomic Method Detects Early Signs of Pancreatic Cancer
RNA Sequencing Identifies Novel Cell Class Linked to Rheumatoid Arthritis Flares
Plasma Lipidome Investigated in Hereditary Hemochromatosis
Circulating Tumor DNA Associated with Triple-Negative Breast Cancer Recurrence
CtDNA Assay for Cancer Recurrence, MRD Applications Demonstrated
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.







