Molecular Diagnostics
Familial Hypercholesterolemia Tends to Slip Past Genetic Tests
Familial hypercholesterolemia is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein (LDL), in the blood and early cardiovascular disease. The most common mutations diminish the number of functional LDL receptors in the liver. More...10 Jun 2021
Personalized CtDNA Analysis Detects Minimal Residual Disease
Multiple myeloma (MM), is a type of bone marrow cancer. It is called multiple myeloma as the cancer often affects several areas of the body, such as the spine, skull, pelvis and ribs. Minimal residual disease (MRD) is the name given to small numbers of leukemic cells that remain in the person during treatment, or after treatment when the patient is in remission. More...08 Jun 2021
Analytic Validation and Clinical Utilization of Comprehensive Genomic Profiling Test
Cancer has a high clinical burden and oncology therapies are expensive. It is estimated that 1,898,160 new cancer cases will be diagnosed and over 608,570 deaths are projected to occur in the USA in 2021. The prevalence of cancer is expected to rise over time, providing an expanding unmet need for genomic tests to help physicians treat patients in a more precise manner. More...02 Jun 2021
Colorectal Cancer Relapse Predicted by ctDNA Clearance
Colorectal cancer (CRC) is the third most common cancer around the world with more than 1.9 million new cases diagnosed annually. CRC is also the second leading cause of cancer-related deaths with a 5-year mortality rate of about 40%. More...01 Jun 2021
Urinary Interleukin-8 May Be the Ultimate Bladder Cancer Biomarker
A recently published study established that the urinary protein interleukin-8 (IL-8) not only distinguished bladder cancer from controls, it also discriminated high grade from low grade disease, and the successive clinical stages of bladder cancer. More...01 Jun 2021
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In Other News
Plasma-Based Algorithm Accurately Predicts Likelihood of Developing Alzheimer’s Disease
Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection
Early Warning Biomarker Proteins Appear Years or Decades Before Alzheimer’s Disease Symptoms
Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma
Measurement of Oxidized Serum Albumin for Diagnosis of Diabetic Kidney Disease
Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection
Rapid, Automated Test Detects Gonorrhea and Determines Antibiotic Susceptibility
Loss of Function Mutations in GEMIN5 Causes Neurodevelopmental Disorder
Elevated Cytokine Levels Linked to Future Development of Myocardial Infarction
New Blood Test Promises Biopsy-Free Colon Cancer Diagnosis
A Novel Capsule-Based Smell Test for Diagnosis of Neurological and Respiratory Diseases
Genetic Background and Clinicopathologic Features Established for Adult-Onset Nephronophthisis
LAMP Assay Developed to Diagnose High HBV DNA Levels
Protein Biomarker Increases Sensitivity of a Urine-based Prostate Cancer Test
Blood-based Liquid Biopsy Detects Lymph Node Metastasis in Colorectal Cancer Patients
GPS Assay Associated with Long-Term Prostate Cancer Outcomes
A Rapid Metabolomic Test for Early Diagnosis of Myocardial Infarction
Genetic Factors Linked to Severe COVID-19, Viral Infections in Children
New Genetic Factors Involved in Sudden Unexpected Death in Children
Novel Urine-based Liquid Biopsy for Early Detection of Aggressive Prostate Cancer
Serum Amyloid A Levels Linked to Likelihood of Developing Severe COVID-19
Different Methods Compared for Isolating Fungal DNA
Digital PCR Improves BCR-ABL1 Detection in Chronic Myeloid Leukemia
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
