Molecular Diagnostics
Elevated Galectin-1 Levels in Sepsis Reflect Danger of Cytokine Storm Development
Increased concentration of the beta-galactoside-binding protein “galectin-1” in sera from human sepsis patients has been found to be a novel biomarker for cytokine storms that may occur in cases with runaway sepsis. More...11 Jan 2021
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Hematopoietic stem-cell transplantation (HSCT) is the only curative treatment for patients with hematological malignant and non-malignant diseases. There are more than 50,000 stem cell transplants are carried out annually worldwide and the number is increasing. More...07 Jan 2021
Chitotriosidase Expression in Sarcoidosis Limited by Gene Expression
Sarcoidosis is a multisystem granulomatous disease which affects individuals worldwide of all ages irrespective of ethnicity or race. It is often recognized accidentally when a routine chest radiographic picture shows bilateral hilar lymphadenopathy. More...06 Jan 2021
Plasma Serglycin Levels Evaluated for Diabetic Retinopathy Diagnosis
Diabetic retinopathy (DR), a microvascular complication caused by chronic diabetes mellitus (DM), is a significant threat to vision in adults, which may even lead to blindness and retinal detachment. The clinical symptoms of DR include fibrosis, capillary obstruction, neovascularization, and increased vascular permeability. More...04 Jan 2021
Single-Cell Transcriptome Links Gut Development, Pediatric Crohn's Disease
Development of the human intestine is a highly complex process that requires synergy between a wide range of cell types. Importantly, environmentally triggered alterations in early development have been implicated in a range of immune-mediated pathologies, including inflammatory bowel diseases (IBD). More...29 Dec 2020
Rare Genetic Variants Can Contribute to Ischemic Heart Failure
Heart failure affects about 40 million people globally, and most cases are due to ischemic heart disease, hypertension, or cardiomyopathies. Cardiomyopathies have been traced to rare variants in genes that encode sarcomere or cytoskeletal proteins, channels, or desmosomes, while genome-wide association studies have underscored common variants linked to heart failure. More...29 Dec 2020
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Panel of Urinary Peptides Used to Diagnose Liver Fibrosis
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Blood Biomarker Protein Correlates with Severity of Brain Damage in Stroke Patients
COVID-19 Lung Damage Caused by Persistence of Abnormal Cells
Levels of MicroRNAs in Saliva Are Diagnostic for Mild Traumatic Brain Injury
Methylated DNA Profiling Explored for Prenatal Testing Applications
CRP Tracking Predicts Potential Outcome for Hospitalized COVID-19 Patients
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
A New Approach for Rapid Detection of Acute Kidney Injury in Children
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