Molecular Diagnostics
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
For kidney transplant recipients, prompt and accurate detection of transplant rejection is vital for timely intervention. Unfortunately, the gold standard for diagnosis of rejection is kidney biopsy, an invasive procedure. More...30 Mar 2020
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Germline genetic testing for pathogenic variants (PVs) in cancer susceptibility genes after breast cancer diagnosis may inform cancer treatment, prevention, and testing of relatives. Postmenopausal women with breast cancer had a threefold higher prevalence of pathogenic variants in breast cancer-associated genes than their cancer-free counterparts. More...26 Mar 2020
Kidney Disease Reveals DNA Variants Associated with Diabetic Nephropathy
Diabetic kidney disease is a serious complication that develops in some people with both Type 1 and Type 2 diabetes. It affects the kidneys' ability to filter extra water and waste products from the body and leads to high blood pressure, swollen extremities, loss of concentration, fatigue and could end in kidney failure. More...26 Mar 2020
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
The concept of creating bespoke or personalized mutation panels to use for cancer recurrence detection and residual disease monitoring is not new at this point. Scientists began piloting these methods several years ago, initially tracking single mutations and then collections of alterations derived from tumor sequencing data. More...25 Mar 2020
Plasma Virome of Brazilians with Unexplained Symptoms of Infection
Deep sequencing of nucleic acids in clinical samples now allows the identification of any known infectious agents, resulting in improved diagnostic capabilities. Blood from healthy people with high exposure to viral infections has also been analyzed using metagenomics. More...25 Mar 2020
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In Other News
Increased Membrane Glycoprotein Level Predicts Lung Cancer Metastasis
EGFR Mutation Assay Cartridges Evaluated
Combination of Genetic Signatures Identifies Ultra High Risk Multiple Myelomas
SARS-CoV-2 Detected in Multiple Sample Types
T-cell Monitoring to Predict Risk of Kidney Transplant Failure
NGS Identifies Genomic Characteristics of Pediatric Leukemia
Methylome Analysis for Noninvasive Prostate Cancer Monitoring
Advanced Urinary Analysis Method Expected to Significantly Reduce Number of Prostate Cancer Biopsies
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Rapid Test Uses Nanopore Sequencing to Diagnose Sepsis by Detecting DNA Released by Pathogenic Microorganisms in the Bloodsteam
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Methylated DNA in Saliva Samples Predicts Likelihood of Developing Childhood Obesity
Noninvasive Urine Test Developed for Prostate Cancer
Presenilin1 Gene Characteristics Used as Alzheimer's Disease Biomarker
Large Genetic Screen Identifies Eight New Variants Linked to Skin Cancer Risk
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Circulating Levels of Phosphorylated Tau Protein Differentiate Alzheimer’s Disease from other Types of Dementia
High-Throughput Isothermal HPV Test Validated
Novel 3-Gene Transcriptional Signature Stratified for Tuberculosis Contacts
Increased Levels of Serum Amyloid-beta Linked to Development of Cardiovascular Disease
Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk
Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis
Identification of a MicroRNA Biomarker Linked to a Childhood Liver Disease
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
