Molecular Diagnostics
Novel Inherited Mutation Predisposes Children to Medulloblastoma
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts for 5% to 10% of cancer diagnoses in children. More...16 Apr 2020
SARS-CoV-2 Found in Sputum/Feces After Negative Pharyngeal Specimens
The outbreak of coronavirus disease 2019 (COVID-19) has become a global public health problem. In the absence of a specific therapy or vaccine, timely diagnosis and the establishment of a sufficient isolation period for infected individuals are critical to containment efforts. More...14 Apr 2020
Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) is a lung disorder characterized by high blood pressure in the pulmonary arteries. In this instance, “idiopathic” means that the cause of the pulmonary artery hypertension is unknown. More...14 Apr 2020
Liquid Biopsy Lung Cancer Screening Method Developed
Genomic blood tests for cancer screening and early detection have become the focus of attention in the molecular diagnostic space, though most activity so far has been either toward pan-cancer screening tools, or in a few other specific tumor types like colorectal cancer, where tests hope to vie against colonoscopy and existing stool-based methods. More...09 Apr 2020
Circulating RNA Biomarker Predicts Likelihood of Developing Alzheimer’s Disease
Elevated levels of a circulating RNA biomarker were found to be characteristic for individuals with Alzheimer’s disease (AD) and could be used to predicate whether an asymptomatic person would be likely to develop the disorder. More...09 Apr 2020
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical pre-cancer and cancer. The role of the cervicovaginal microbiome (CVM) in the natural history of HR-HPV has been investigated. More...08 Apr 2020
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In Other News
Early Tumor Detection by Analysis of Circulating Free DNA Methylation Patterns
Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples
Rapid, Paper-Based Test Detects Coronavirus in Sewage and Wastewater
Hybrid Liquid Biopsy Platform Enables Tracking and Monitoring of Circulating Tumor Cells
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Kidney Disease Reveals DNA Variants Associated with Diabetic Nephropathy
Combined Maternal and Fetal Gene Variants Predict Pre-Eclampsia Risk
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
Plasma Virome of Brazilians with Unexplained Symptoms of Infection
Increased Membrane Glycoprotein Level Predicts Lung Cancer Metastasis
EGFR Mutation Assay Cartridges Evaluated
Combination of Genetic Signatures Identifies Ultra High Risk Multiple Myelomas
SARS-CoV-2 Detected in Multiple Sample Types
T-cell Monitoring to Predict Risk of Kidney Transplant Failure
NGS Identifies Genomic Characteristics of Pediatric Leukemia
Methylome Analysis for Noninvasive Prostate Cancer Monitoring
Advanced Urinary Analysis Method Expected to Significantly Reduce Number of Prostate Cancer Biopsies
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Rapid Test Uses Nanopore Sequencing to Diagnose Sepsis by Detecting DNA Released by Pathogenic Microorganisms in the Bloodsteam
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
