Molecular Diagnostics
Molecular Assays Compared For MRD Detection In B-ALL
B-cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy in children, and it may be associated with gene alterations that regulate B-cell development. The prognostic significance of minimal residual disease (MRD) in children with acute lymphoblastic leukemia (ALL) has been demonstrated. More...11 Aug 2021
Advanced Sequencing Techniques Determine Cancer Genome Variants in Young Patients
A recent paper described a three-platform sequencing approach, including whole genome (WGS), exome, and RNA sequencing, that was used to examine tumor and germline genomes from prospectively identified children with newly diagnosed or relapsed/refractory cancers. More...03 Aug 2021
ALDOA and FH4 Antibodies Associated with Cerebrovascular Disease
Ischemic stroke, including transient ischemic attack (TIA) and cerebral infarction (CI), is the most globally recognized cerebrovascular disorder, and is a serious health problem in the aging society. CI is an episode of neurological dysfunction caused by focal brain infarction, often resulting in fatality and disability. Patients with TIA are at a high risk of CI. More...28 Jul 2021
Highly Sensitive Genetic Test for Glaucoma Developed
In open-angle glaucoma, the angle in the eye where the iris meets the cornea is as wide and open as it should be, but the eye’s drainage canals become clogged over time, causing an increase in internal eye pressure and subsequent damage to the optic nerve. More...28 Jul 2021
Neurofilament Light Chain Levels Increase Accuracy of Neurodegenerative Disease Detection
Increased accuracy in early detection of neurodegenerative diseases was obtained by adding determination of levels of neurofilament light chain (NfL) protein in cerebrospinal fluid (CSF) to the framework that combines three Alzheimer's disease biomarkers - pathologic amyloid plaques (A), tangles (T), and neurodegeneration (N), collectively called ATN. More...27 Jul 2021
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APOE Gene Influences Alzheimer's Symptoms, Biomarkers in Down Syndrome
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Optical Genome Mapping Enables Constitutional Chromosomal Aberration Detection
Serum Biomarkers Enable Tracing the Progress of COVID-19 Infections
Rectal Colonization by Klebsiella Leads to Different Risks for Bacteremia
Telomerase Reverse Transcriptase Protein Expression Evaluated for Melanomas
Metabolomic Analytical Approach Identifies Multiple Neonatal Errors of Metabolism Disorders
Targeted Locus Amplification Validated for Lymphoma
Protein Biomarker Helps Diagnose Pancreatic Cancer
Rotavirus Co-Infection with Diarrheagenic Pathogens Detected by Different Methods
Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection
Genotyping Helps Avoid Needless Bone Marrow Biopsies in African-Americans
A Novel Nanowell Array Sensor for POC Measurement of Stress Hormones
Novel Stool Biomarker Screening Tests Detect Colorectal Cancer and Inflammatory Bowel Disease
Protein Biomarker Blood Test Accurately Detects Alzheimer’s Disease
Sensitive PCR Test Predicts Treatment Response in Metastatic Head and Neck Cancers
Blood-based Liquid Biopsy Test Accurately Detects More Than Fifty Types of Cancer
Circulating Tumor DNA Following Surgery Predicts Bladder Cancer Recurrence
A Nanowire-based Liquid Biopsy Method for Detection of Tumors of the Central Nervous System
The OncoMasTR Test Accurately Identifies Risk of Breast Cancer Recurrence
Highly Sensitive Molecular Test Detects Cases of Tuberculosis
Serum Thrombospondin 2 Identified as Biomarker for Patients at Risk of Nonalcoholic Fatty Liver Disease
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
