Molecular Diagnostics
Loop-Mediated Isothermal Amplification Kit Detects Chagas Disease
Chagas disease (CD), also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that affects about six to seven million people worldwide, mainly in endemic areas of 21 Latin American countries. More...07 Sep 2020
Clonal Hematopoiesis Prevalence Determined in Healthy Donors
Clonal hematopoiesis of indeterminate potential (CHIP) is defined as the presence of a clone at more than 2% of variant allele frequency (VAF) in peripheral blood (PB) of individuals with no evidence of hematologic disease. More...02 Sep 2020
Streamlined Method for Telomere Length Measurement Opens New Cancer Diagnostic Opportunities
In a novel approach to cancer diagnosis, researchers have developed a high-throughput digital real-time PCR method for rapidly measuring the absolute lengths and quantities of individual telomere molecules. More...01 Sep 2020
Pan-Cancer Study Reveals Extrachromosomal DNA Frequency
Extrachromosomal circular DNA (eccDNA) are circular DNA found in human, plant and animal cells in addition to chromosomal DNA. eccDNA originate from chromosomal DNA and can be from 50 base pairs to several mega-base pairs in length and encode regulatory elements and several full genes. More...01 Sep 2020
New Pooling Strategy Increases Efficiency and Reduces Cost of COVID-19 PCR Tests
A new way of manipulating samples for COVID-19 testing of asymptomatic and symptomatic individuals provides both an eight-fold increase in testing efficiency, as well as an eight-fold reduction in test costs. More...31 Aug 2020
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In Other News
An Extracellular Vesicle-Based Liquid Biopsy for Early Cancer Detection
Loop-Mediated Isothermal Amplification-Assay Rapidly Diagnoses COVID-19
Newborn Exome Sequencing Locates Inborn Errors of Metabolism
Gene Panel Predicts Likely Survival Time for Ovarian Cancer Patients
Single-Cell Analysis Provides New Insights into Mitochondrial Diseases
Isoform-Specific Loss Of Dystonin Causes Charcot-Marie-Tooth Disease
Blood Bank NAT-Based Assay Prevents Transfusion-Transmitted Malaria
Circulating tumor DNA Test Predicts Immunotherapy Response
Lab Profiles Differentiate MIS-C From Severe Pediatric COVID-19
Two Simple Methods Prepare DNA Suitable For Digital PCR
Elevated Glycolated Hemoglobin in Young People Predicts Likelihood of Diabetes or Cardiovascular Disease in Adulthood
Diagnostic Test Identifies Resistance Mutation that Enables Use of Inexpensive, Single Dose Gonorrhea Drug
Panel of Five Serum Biomarkers Identifies COVID-19 Patients at High Risk to Develop Serious Complications
Host Genetic, Environmental Factors Influence Urinary Tract Microbiome
Automated Malaria Diagnosis Enhanced by Deep Neural Networks
Phosphorylated-Tau Blood Test Identifies Asymptomatic Alzheimer’s Disease
Somatic Evolution Identified in Non-Neoplastic IBD-Affected Colon
Liquid Biopsy Test Accurately Detects Cancer in Nonsymptomatic Individuals
Elevated Angiotensin 1–7/Angiotensin II Ratio Predicts Favorable Outcomes in Patients with Heart Failure with Potential Link to COVID-19 Patients
Nanostar Biosensors Use Raman Scattering for Direct Detection of Cancer-Related MicroRNAs
Pediatric Ependymoma Single-Cell Analysis Signatures Linked to Outcomes
Combined Proteomic/Genomic Method Detects Early Signs of Pancreatic Cancer
RNA Sequencing Identifies Novel Cell Class Linked to Rheumatoid Arthritis Flares
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.