Molecular Diagnostics
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
The concept of creating bespoke or personalized mutation panels to use for cancer recurrence detection and residual disease monitoring is not new at this point. Scientists began piloting these methods several years ago, initially tracking single mutations and then collections of alterations derived from tumor sequencing data. More...25 Mar 2020
Plasma Virome of Brazilians with Unexplained Symptoms of Infection
Deep sequencing of nucleic acids in clinical samples now allows the identification of any known infectious agents, resulting in improved diagnostic capabilities. Blood from healthy people with high exposure to viral infections has also been analyzed using metagenomics. More...25 Mar 2020
Increased Membrane Glycoprotein Level Predicts Lung Cancer Metastasis
A protein found in extracellular vesicles (Evs) shed by lung cancer cells was found to be an effective, relatively noninvasive biomarker for the early detection of lung cancer metastasis and could shape the direction of therapeutic decisions. More...25 Mar 2020
Combination of Genetic Signatures Identifies Ultra High Risk Multiple Myelomas
Combining two panels of genetic biomarkers enabled cancer researchers to identify multiple myeloma patients at “ultra high risk” of progression of the disease and probable lack of response to lenalidomide, the primary drug used to treat it. More...24 Mar 2020
SARS-CoV-2 Detected in Multiple Sample Types
An epidemic of respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and has spread to other countries. Real-time reverse transcriptase–polymerase chain reaction (rRT-PCR) of nasopharyngeal swabs typically has been used to confirm the clinical diagnosis. More...23 Mar 2020
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In Other News
NGS Identifies Genomic Characteristics of Pediatric Leukemia
Methylome Analysis for Noninvasive Prostate Cancer Monitoring
Advanced Urinary Analysis Method Expected to Significantly Reduce Number of Prostate Cancer Biopsies
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Rapid Test Uses Nanopore Sequencing to Diagnose Sepsis by Detecting DNA Released by Pathogenic Microorganisms in the Bloodsteam
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Methylated DNA in Saliva Samples Predicts Likelihood of Developing Childhood Obesity
Noninvasive Urine Test Developed for Prostate Cancer
Presenilin1 Gene Characteristics Used as Alzheimer's Disease Biomarker
Large Genetic Screen Identifies Eight New Variants Linked to Skin Cancer Risk
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Circulating Levels of Phosphorylated Tau Protein Differentiate Alzheimer’s Disease from other Types of Dementia
High-Throughput Isothermal HPV Test Validated
Novel 3-Gene Transcriptional Signature Stratified for Tuberculosis Contacts
Increased Levels of Serum Amyloid-beta Linked to Development of Cardiovascular Disease
Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk
Leukemic Stem Cell Score Predicts Myelodysplastic Syndrome Prognosis
Identification of a MicroRNA Biomarker Linked to a Childhood Liver Disease
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Researchers Identify Genes Linked to the Development of Monogenic Diabetes
Fetal Cell-Based NIPT Demonstrated by Droplet Digital PCR
Point-Of-Care Molecular Tests Compared for Pediatric Influenza
Genetic Risk Factors Found in Gestational Diabetes
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
