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Molecular Diagnostics

Image: Micrograph showing a prostate cancer (conventional adenocarcinoma) with perineural invasion (Photo courtesy of Wikimedia Commons)

Study Confirms Value of the MyProstateScore Urine Test for Prostate Cancer Screening

A recent paper confirmed that the MyProstateScore test could be used with confidence to detect clinically significant (grade group higher than 2) prostate cancers when compared to commonly used prostate specific antigen-based diagnostic screening. More...
22 Feb 2021
Image: TruSight Oncology 500 is a next-generation sequencing (NGS) assay that enables in-house comprehensive genomic profiling of tumor samples it accurately measures key current immuno-oncology biomarkers: microsatellite instability (MSI) and tumor mutational burden (TMB) (Photo courtesy of Illumina).

Next Generation Sequencing Finds More Gene Mutations for Leukemia

Myeloid malignancies are characterized by uncontrolled proliferation and/or defects in differentiation of abnormal myeloid progenitor cells. Myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs) are often thought to be precursors to a higher grade myeloid malignancies, namely acute myeloid leukemia (AML). More...
18 Feb 2021
Image: Exome sequencing workflow: Double-stranded genomic DNA is fragmented by sonication. Linkers are then attached to the DNA fragments, which are then hybridized to a capture microarray designed to target only the exons (Photo courtesy of SarahKusala).

Exome Sequencing Identified Pathogenic Variants in Cerebral Palsy Patients

Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood. Signs and symptoms vary among people and over time. Often, symptoms include poor coordination, stiff muscles, weak muscles, and tremors. More...
18 Feb 2021
Image: The crystal structure of the nucleosome core particle (Photo courtesy of Wikimedia Commons)

Analysis of Cell-free DNA in the Blood May Replace Examination of Biopsy Specimens for Disease Diagnosis

A recent paper described a blood-based liquid biopsy method for detection of a wide variety of diseases including several types of cancer. More...
16 Feb 2021
Image: Atypical lipomatous tumor/well-differentiated liposarcoma (left-hand); lipoma (right-hand) (Photo courtesy of Dr.Tony Ng, The University of British Columbia)

NanoString Technology Modernizes Liposarcoma Diagnostics

A recently published study showed that a newer NanoString-based method could allow for more rapid and cost-efficient diagnosis of liposarcomas than the commonly used fluorescence in situ hybridization (FISH) method. More...
15 Feb 2021
Image: The Technothrombin TGA is a thrombin generation assay (TGA) based on monitoring the formation of thrombin by means of a fluorogenic substrate upon activation of the coagulation cascade by tissue factor (Photo courtesy of Technoclone).

TFP Inhibitor Levels Elevated in Bleeding Tendency Patients

Mild to moderate bleeding disorders (MBDs) are characterized by symptoms such as epistaxis, easy bruising, or menorrhagia, but bleeding can also be severe under certain circumstances such as hemorrhage after surgery or birth. More...
11 Feb 2021
Image: The RealStar Zika Virus RT-PCR Kit 1.0 is an in vitro diagnostic test, based on real-time PCR technology, for the qualitative detection of Zika virus specific RNA in human serum or urine (Photo courtesy of Altona Diagnostics).

Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes

The recent worldwide epidemic confirmed maternal–fetal transmission of Zika virus (ZIKV) and its association with adverse perinatal outcomes, particularly severe central nervous system lesions and fetal losses. More...
10 Feb 2021
New
Gold Member
Aspiration System
VACUSAFE
New
Gold Member
Automatic Hematology Analyzer
CF9600
New
Prefilled Tubes
Prefilled 5.0ml Tubes
New
Manual Pipetting Aid
Pipette Controllers macro


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.