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Molecular Diagnostics

Image: Structure of the apolipoprotein(a) protein (Photo courtesy of Wikimedia Commons)

Elevated Levels of Lipoprotein(a) Predict Increased Risk for Developing Cardiovascular Diseases

Measurement of the blood biomarker lipoprotein(a) predicts risk of developing cardiovascular disease as well as determination of such standard factors as cholesterol and triglycerides. More...
12 Oct 2020
Image: The HiSeq X Series incorporates patterned flow cell technology to generate an exceptional level of throughput for whole-genome sequencing. (Photo courtesy of Illumina).

Genome Sequencing Evaluated in Children with Unexplained Medical Complexity

Children with medical complexity (CMC) have at least one chronic condition, depend on a technological tool like a ventilator or require intravenous nutrition or drugs, are under the care of multiple subspecialists, and have substantial healthcare use. More...
08 Oct 2020
Image: The Applied Biosystems ViiA 7 Real-Time PCR System combines all of the qPCR features in a single high performance instrument (Photo courtesy of Thermo Fisher Scientific).

Blood-Based Test Accurately Identifies Viral Infection Before Symptoms Develop

Acute viral infections are one of the most common reasons for visits to primary care physicians in high-income countries. The usefulness of traditional pathogen-focused diagnostic methods for viral infection (e.g., culture, serology, antigen detection, and PCR) is limited by the fact they can be slow, costly, and restricted in terms of breadth of pathogens detected. More...
07 Oct 2020
Image: Photomicrograph of histology of a poorly differentiated squamous cell carcinoma (SCC) that is p16 positive (Photo courtesy of Nephron).

HPV, p16 Offers Different Prognostic Clues in Oropharyngeal Cancer

Human papillomavirus infection (HPV infection) is an infection caused by human papillomavirus (HPV), a DNA virus from the Papillomaviridae family. About 90% of HPV infections cause no symptoms and resolve spontaneously within two years. More...
07 Oct 2020
Image: This illustration reveals the ultrastructural morphology exhibited by coronaviruses. Note the protein spikes that adorn the outer surface of the virus, which impart the look of a corona surrounding the virion, when viewed through an electron microscope (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)

Bacteriophage Analysis Technique Reveals Details of COVID-19’s Impact on the Immune System

An analytical technique that can determine which of more than 1,000 different viruses have infected a person, has been utilized for a detailed study of the SARS-CoV-2 (COVID-19) virus and its impact on the immune system. More...
06 Oct 2020
Image: Illustration of the heart with magnification of the artery (Photo courtesy of American Heart Association)

Large Genome-Wide Association Study Identifies Novel Abdominal Aortic Aneurysm Risk Loci

A recent report identified novel genetic associations for abdominal aortic aneurysm (AAA) with therapeutic implications and identified a subset of the population at significantly increased genetic risk of AAA that was independent of family history. More...
05 Oct 2020
Image: Cryptosporidium oocysts and the larger Giardia cysts stained by Crypto/Giardia IFA kit (Photo courtesy of Cellabs).

Smartphone Microscopic Method Detects Cryptosporidium and Giardia

Food and water-borne illness arising from the consumption of contaminated food and water are serious health hazards globally. Cryptosporidium and Giardia are the major food and water‒borne parasites. The infection occurs mainly by (oo)cyst phase of the parasites. More...
30 Sep 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.