Molecular Diagnostics
Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples
Posterior oropharyngeal saliva samples are a non-invasive specimen more acceptable to patients and health-care workers. Unlike severe acute respiratory syndrome, patients with COVID-19 had the highest viral load near presentation, which could account for the fast-spreading nature of this epidemic. More...06 Apr 2020
Hybrid Liquid Biopsy Platform Enables Tracking and Monitoring of Circulating Tumor Cells
By creating a hybrid microfluidic liquid biopsy platform that incorporates atomic force microscopy (AFM), cancer researchers have captured and characterized circulating tumor cells (CTCs), a technique which should prove useful in the diagnosis and prognosis of prostate cancer as well as other forms of cancer. More...01 Apr 2020
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Epidermal growth factor receptor (EGFR) gene mutations that confer sensitivity to tyrosine kinase inhibitors (TKI) in non-small cell lung carcinomas paved the way for a precision medicine approach in this neoplastic form. More...31 Mar 2020
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
For kidney transplant recipients, prompt and accurate detection of transplant rejection is vital for timely intervention. Unfortunately, the gold standard for diagnosis of rejection is kidney biopsy, an invasive procedure. More...30 Mar 2020
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Germline genetic testing for pathogenic variants (PVs) in cancer susceptibility genes after breast cancer diagnosis may inform cancer treatment, prevention, and testing of relatives. Postmenopausal women with breast cancer had a threefold higher prevalence of pathogenic variants in breast cancer-associated genes than their cancer-free counterparts. More...26 Mar 2020
Kidney Disease Reveals DNA Variants Associated with Diabetic Nephropathy
Diabetic kidney disease is a serious complication that develops in some people with both Type 1 and Type 2 diabetes. It affects the kidneys' ability to filter extra water and waste products from the body and leads to high blood pressure, swollen extremities, loss of concentration, fatigue and could end in kidney failure. More...26 Mar 2020
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In Other News
Combined Maternal and Fetal Gene Variants Predict Pre-Eclampsia Risk
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
Plasma Virome of Brazilians with Unexplained Symptoms of Infection
Increased Membrane Glycoprotein Level Predicts Lung Cancer Metastasis
EGFR Mutation Assay Cartridges Evaluated
Combination of Genetic Signatures Identifies Ultra High Risk Multiple Myelomas
SARS-CoV-2 Detected in Multiple Sample Types
T-cell Monitoring to Predict Risk of Kidney Transplant Failure
NGS Identifies Genomic Characteristics of Pediatric Leukemia
Methylome Analysis for Noninvasive Prostate Cancer Monitoring
Advanced Urinary Analysis Method Expected to Significantly Reduce Number of Prostate Cancer Biopsies
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Rapid Test Uses Nanopore Sequencing to Diagnose Sepsis by Detecting DNA Released by Pathogenic Microorganisms in the Bloodsteam
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Methylated DNA in Saliva Samples Predicts Likelihood of Developing Childhood Obesity
Noninvasive Urine Test Developed for Prostate Cancer
Presenilin1 Gene Characteristics Used as Alzheimer's Disease Biomarker
Large Genetic Screen Identifies Eight New Variants Linked to Skin Cancer Risk
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Circulating Levels of Phosphorylated Tau Protein Differentiate Alzheimer’s Disease from other Types of Dementia
High-Throughput Isothermal HPV Test Validated
Novel 3-Gene Transcriptional Signature Stratified for Tuberculosis Contacts
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.