Molecular Diagnostics
ctDNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases
A BRAF mutation is a change in a BRAF gene. That change in the gene can lead to an alteration in a protein that regulates cell growth that could allow the melanoma to grow more aggressively. Approximately half of melanomas carry this mutation and are referred to as mutated, or BRAF positive. More...02 Mar 2021
Rapid Lateral Flow Assays Detect COVID-19 Variants and Differentiate COVID-19 from Other Respiratory Viral Diseases
A recent publication reported the development of two rapid diagnostic tests - one that detects COVID-19 variants and one that differentiates COVID-19 from other respiratory viral diseases. More...02 Mar 2021
Elevated Plasma Levels of Glial Fibrillary Acidic Protein Indicate Increased Alzheimer’s Risk
A recent study has demonstrated that plasma levels of the protein GFAP (glial fibrillary acidic protein) are elevated in cognitively normal older adults at risk of developing Alzheimer’s disease. More...01 Mar 2021
Pulse-Controlled Amplification Tested for Infectious Disease Diagnostics
Molecular diagnostics has become essential in the identification of many infectious and neglected diseases, and the detection of nucleic acids often serves as the gold standard technique for most infectious agents. More...25 Feb 2021
22-Gene Genomic Classifier Validated in Recurrent Prostate Cancer Patients
When prostate cancer has been detected or has returned following initial treatment with surgery, radiation therapy and/or hormone therapy, it is said to be recurrent or relapsed. Treatment of recurrent prostate cancer depends on what treatment a patient has previously received and the extent of the cancer. More...25 Feb 2021
Plasma or Urine Liquid Biopsy Tests May Guide Colorectal Cancer Treatment
A recent paper suggested that liquid biopsy examination of blood or urine could aid in evaluating the effectiveness of therapy for colorectal cancers that had begun to metastasize beyond the site of the original tumor. More...23 Feb 2021
Proteogenomic and Metabolomic Studies Characterize Human Glioblastoma
Glioblastoma (GBM) is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. Glioblastoma can occur at any age, but tends to occur more often in older adults. It can cause worsening headaches, nausea, vomiting and seizures. More...23 Feb 2021
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In Other News
Study Confirms Value of the MyProstateScore Urine Test for Prostate Cancer Screening
Next Generation Sequencing Finds More Gene Mutations for Leukemia
Exome Sequencing Identified Pathogenic Variants in Cerebral Palsy Patients
Analysis of Cell-free DNA in the Blood May Replace Examination of Biopsy Specimens for Disease Diagnosis
NanoString Technology Modernizes Liposarcoma Diagnostics
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes
Early Plasma Biomarkers Discovered for Alzheimer's Disease
TAP1 Gene Polymorphisms Associated with Recurrent Respiratory Papillomatosis
Liquid Biopsy Allows Monitoring of COVID-19 Damage to Cells, Tissues, and Organs
Blood Test Detects Early Colorectal Adenomas
Precise Measurement of DNA Length Polymorphisms Used to Diagnose Acute Myeloid Leukemia
Liquid Biopsy Predicts Colon Cancer Relapse Months Earlier
Cell-Free DNA Detects Heart Allograft Acute Rejection
AI-guided Immunoassay Measures Maternal Autoantibodies to Predict Likelihood of Autism Spectrum Disorder
A Rapid AI-based Screening Test for Prostate Cancer Biomarkers in Urine
ABO Histo-Blood Groups Influence Makeup of Gut Microbiome
Specific RUNX1 Mutations Cause Different Disease Types
Study Confirms Performance of Rapid Stool Test for Detection of Colorectal Cancer
Monitoring of Urinary Eicosanoids Distinguishes Mild and Severe Asthma
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
Panel of MicroRNAs Differentiates Uncomplicated and Severe Malaria in Children
Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles
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