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Molecular Diagnostics

Image: Structure of the angiotensin-converting enzyme 2 (ACE2) protein (Photo courtesy of Wikimedia Commons)

Higher Concentrations of COVID-19 Receptor Protein Found in Men’s Plasma

Results of a large-scale study revealed that plasma concentrations of angiotensin-converting enzyme 2 (ACE2) were higher in men than in women, but use of neither an ACE inhibitor nor an angiotensin receptor blocker (ARB) was associated with higher plasma ACE2 concentrations. More...
18 May 2020
Image: Schematic diagram of circulating tumor DNA (ctDNA) which is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized. Once ctDNA is isolated, it can be sequenced for mutational analysis (Photo courtesy of Rachel June Wong).

Blood Test Shows Promise for Predicting Cancer

Early detection of most cancers is an elusive and daunting task; nevertheless, it has remained a top priority for the cancer research community. Detecting cancer early has manifold advantages: it can increase a patient’s chances of successful treatment, prolong their survival, and substantially improve their quality of life. More...
14 May 2020
DIASOURCE (A Biovendor Company)
Image: High magnification micrograph of diffuse proliferative lupus nephritis (Photo courtesy of Wikimedia Commons).

Knowing the Ethnic Specificity of Urinary Biomarker Proteins Could Refine Diagnosis of Lupus Nephritis

A study of biomarkers in the urine of African-Americans, Caucasian, and Asian patients suffering from lupus nephritis identified distinct patterns of proteins associated with each specific ethnicity, which may be useful in diagnosing the disorder. More...
13 May 2020
Image: Scanning electron microscope image (500x magnification) of pollen grains from a variety of common plants (Photo courtesy of Dartmouth Electron Microscope Facility, Dartmouth College (via Wikimedia Commons)

Biomarker Panel Predicts Severity of Pollen Allergy Symptoms

A team of German researchers has identified a panel of biomarkers that predicts the severity of allergic symptoms even before the start of the pollen season. More...
12 May 2020
Image: Multicancer Blood Test Aids Screen for Cancer Guide Intervention (Photo courtesy of fotoquique/Depositphotos).

Multicancer Blood Test Aids Screen for Cancer Guide Intervention

As minimally invasive screening tests, liquid biopsies could help reduce cancer-specific morbidity and mortality through earlier detection. However, there is debate on how to effectively screen large populations for cancer, including individuals who do not have symptoms or history of the disease. More...
12 May 2020
Image: Photograph of the CARMEN microwell chip (Photo courtesy of Michael James Butts)

CRISPR-Based Microarray System Enables Massive Testing for Viral Pathogens

A novel microfluidic nucleic acid-based diagnostic system is capable of detecting a specific virus from a catalog of more than 160 human pathogens, including the COVID-19 coronavirus, simultaneously in more than 1,000 samples. More...
11 May 2020
Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention)

A Series of Sensitive and Specific DNA-Based Assays Detects and Differentiates Salmonella Serotypes

A team of Australian researchers developed a series of sensitive and specific assays to detect and identify different serotypes (serovars) of Salmonella, a common cause of bacterial foodborne disease worldwide. More...
07 May 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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