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Recent News Expo Medica 2025 Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Molecular Diagnostics

Image: The QX200 Droplet Digital Polymerase Chain Reaction (PCR) Systems provide ultrasensitive and absolute nucleic acid quantification. (Photo courtesy of Bio-Rad)

Digital PCR Improves BCR-ABL1 Detection in Chronic Myeloid Leukemia

Specific targeting of the Bcr-Abl1 enzyme by tyrosine kinase inhibitors (TKI) revolutionized the management of chronic myeloid leukemia (CML) to the point that TKIs can offer near normal life expectancy for CML patients. More...
22 Apr 2021
Image: Histopathology from a transurethral biopsy of urothelial carcinoma of the urinary bladder (Photo courtesy of KGH)

RNA-Sequencing Predicts Immunotherapy Success in Bladder Cancer

Urothelial carcinoma, also known as transitional cell carcinoma (TCC), is by far the most common type of bladder cancer. Urothelial cells also line other parts of the urinary tract, such as the part of the kidney that connects to the ureter (called the renal pelvis), the ureters, and the urethra. More...
22 Apr 2021
Image: Representation of the molecular structure of the cathepsin B (catB) protein (Photo courtesy of Wikimedia Commons)

An Ultrasensitive Assay for Measurement of Levels of Cathepsin B in the Blood

A novel digital enzyme-linked immunosorbent assay (ELISA) has been developed for the differential detection of cathepsin B from samples of serum or plasma. More...
21 Apr 2021
Image: HIV assembling on the surface of an infected macrophage. The HIV virions have been marked with a green fluorescent tag and then viewed under a fluorescent microscope (Photo courtesy of Wikimedia Commons)

A Method for Accurately Assessing the Latent Virus Reservoir in Chronic HIV Patients

A modified version of the PCR test can determine the quantity and quality of inactive human immunodeficiency virus (HIV) in the genes of individuals suffering from chronic HIV. More...
20 Apr 2021
Image: Darkfield photomicrograph (magnified 400x) showing the presence of the spirochaete Borrelia burgdorferi, which is the pathogen that causes Lyme disease (Photo courtesy of [U.S.] Centers for Disease Control and Prevention via Wikimedia Commons)

Sensitive PCR Test Detects Early Stage Lyme Disease

A highly sensitive blood test detects the bacteria that causes Lyme disease in early stages of the infection, when treatment can prevent the development of serious or fatal consequences of the chronic disease. More...
19 Apr 2021
Image: Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality (Photo courtesy of Randox Laboratories)

Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality

Randox Laboratories’ (Crumlin, UK) Discovery, a diagnostic analyzer which can consolidate molecular and immunoassay testing on one compact benchtop platform, has received the 2021 Red Dot Award for High Design Quality. More...
16 Apr 2021
Image: Immune T cells lymphocytes can seek and destroy a cell (green) infected with and making copies of SARS-CoV-2 (yellow) (Photo courtesy of US National Institute of Allergy and Infectious Diseases)

T Cells Recognize Recent SARS-CoV-2 Variants

Due to the proofreading ability of the coronavirus (CoV) RNA-dependent RNA polymerase, the evolution of the global SARS-CoV-2 viral population during the current pandemic has been relatively constrained as compared to other endemic RNA viruses that do not possess this ability. More...
15 Apr 2021
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