Molecular Diagnostics

Digital PCR Improves BCR-ABL1 Detection in Chronic Myeloid Leukemia
Specific targeting of the Bcr-Abl1 enzyme by tyrosine kinase inhibitors (TKI) revolutionized the management of chronic myeloid leukemia (CML) to the point that TKIs can offer near normal life expectancy for CML patients. More...22 Apr 2021

RNA-Sequencing Predicts Immunotherapy Success in Bladder Cancer
Urothelial carcinoma, also known as transitional cell carcinoma (TCC), is by far the most common type of bladder cancer. Urothelial cells also line other parts of the urinary tract, such as the part of the kidney that connects to the ureter (called the renal pelvis), the ureters, and the urethra. More...22 Apr 2021

![Image: Darkfield photomicrograph (magnified 400x) showing the presence of the spirochaete Borrelia burgdorferi, which is the pathogen that causes Lyme disease (Photo courtesy of [U.S.] Centers for Disease Control and Prevention via Wikimedia Commons) Image: Darkfield photomicrograph (magnified 400x) showing the presence of the spirochaete Borrelia burgdorferi, which is the pathogen that causes Lyme disease (Photo courtesy of [U.S.] Centers for Disease Control and Prevention via Wikimedia Commons)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2021-04-19/GMS-027B.jpg)

Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality
Randox Laboratories’ (Crumlin, UK) Discovery, a diagnostic analyzer which can consolidate molecular and immunoassay testing on one compact benchtop platform, has received the 2021 Red Dot Award for High Design Quality. More...16 Apr 2021

T Cells Recognize Recent SARS-CoV-2 Variants
Due to the proofreading ability of the coronavirus (CoV) RNA-dependent RNA polymerase, the evolution of the global SARS-CoV-2 viral population during the current pandemic has been relatively constrained as compared to other endemic RNA viruses that do not possess this ability. More...15 Apr 2021
In Other News
Novel Lipid Biomarker Detects Senescent Cells
Leukocyte Epigenomics and Artificial Intelligence Predict Late-Onset Alzheimer’s Disease
A Protein Biomarker Aids Cancer Patients by Controlling the Dosage of Highly Toxic Cisplatin
Genome Sequencing Identifies Myeloma Precursor Disease with Progression Risk
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts
Advances in High-Tech Methods for Cervical Cancer Screening
Salivary Diagnostic Signatures of Concussion Found in Male Athletes
A Mass Spectrometry Approach for Monitoring Progress of Multiple Myeloma
Whole-Genome Sequencing Aids Rare Disease Diagnosis
Lupus Genetic Risk Variant Allelic Enhancer Activity Discovered
PCR Method Identifies Microsatellite Instability in Tumor-Derived Samples
Disease Diagnosis Based on Infrared Analysis of Blood Samples
A High-Throughput Single Telomere Length Analysis Approach for Diagnosis of Telomeopathic Diseases
Genome Sequencing More Informative than Cytogenetic Analysis in Myeloid Cancers
Genetic Mutations Identified for Rare VEXAS Syndrome
Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
A Rapid, Non-Invasive Skin Test for Diagnosis of Parkinson’s Disease
Pediatric Pancreatic Cancer Diagnosed from cfDNA Fragments in Urine
Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers
Liquid Biopsy Technique Detects Circulating Tumor Cells in Patients with Non-Small Cell Lung Cancer
Analysis of Urinary Exosome RNA Can Diagnose Kidney Transplant Rejection
Whipple’s Disease Pathogen Found in International Diarrhea Patients
Five Genes Help Predict Lewy Body Dementia
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.








