Molecular Diagnostics
Single-Cell Sequencing Reveals Clonal Diversity Among AML Patients
A growing body of evidence supports the role of clonal diversity in therapeutic resistance, recurrence, and poor outcomes in cancer. Clonal diversity also reflects the history of the accumulation of somatic mutations within a tumor. More...03 Nov 2020
Genetic Alterations Associated with Sporadic Congenital Hydrocephalus
Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with neurosurgical CSF diversion with high morbidity and failure rates. More...02 Nov 2020
Inherited Causes of Clonal Hematopoiesis in Multiplicity of Whole Genomes
The age-related acquisition of somatic mutations that lead to clonal expansion in regenerating hematopoietic stem cell populations has recently been associated with both hematological cancer and coronary heart disease, and this phenomenon is termed clonal hematopoiesis of indeterminate potential (CHIP). More...29 Oct 2020
Single-Molecule Tethering Detects Nucleic Acids and Microorganisms
Detection of microbial nucleic acids in body fluids has become the preferred method for rapid diagnosis of many infectious diseases. However, culture-based diagnostics that are time-consuming remain the gold standard approach in certain cases, such as sepsis. More...29 Oct 2020
Novel Method Reclaims Resolution of Single-Cell RNA-Seq
Single-cell RNA sequencing (scRNA-seq) is a powerful tool to characterize cells. Current scRNA-seq platforms, despite offering high throughput, are inefficient and provide low resolution among distinct cell states and molecular features. More...28 Oct 2020
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Smartphone Microscopic Method Detects Cryptosporidium and Giardia
Epigenetic Markers Predict Type 2 Diabetes Patients Response to Metformin
Endometrium Undergoes Gene Expression Shifts During Menstrual Cycle
Rapid One-Step Assay for Field-Based Detection of Asymptomatic Malaria
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.