Molecular Diagnostics

Higher Concentrations of COVID-19 Receptor Protein Found in Men’s Plasma
Results of a large-scale study revealed that plasma concentrations of angiotensin-converting enzyme 2 (ACE2) were higher in men than in women, but use of neither an ACE inhibitor nor an angiotensin receptor blocker (ARB) was associated with higher plasma ACE2 concentrations. More...18 May 2020

Blood Test Shows Promise for Predicting Cancer
Early detection of most cancers is an elusive and daunting task; nevertheless, it has remained a top priority for the cancer research community. Detecting cancer early has manifold advantages: it can increase a patient’s chances of successful treatment, prolong their survival, and substantially improve their quality of life. More...14 May 2020

Knowing the Ethnic Specificity of Urinary Biomarker Proteins Could Refine Diagnosis of Lupus Nephritis
A study of biomarkers in the urine of African-Americans, Caucasian, and Asian patients suffering from lupus nephritis identified distinct patterns of proteins associated with each specific ethnicity, which may be useful in diagnosing the disorder. More...13 May 2020


Multicancer Blood Test Aids Screen for Cancer Guide Intervention
As minimally invasive screening tests, liquid biopsies could help reduce cancer-specific morbidity and mortality through earlier detection. However, there is debate on how to effectively screen large populations for cancer, including individuals who do not have symptoms or history of the disease. More...12 May 2020

CRISPR-Based Microarray System Enables Massive Testing for Viral Pathogens
A novel microfluidic nucleic acid-based diagnostic system is capable of detecting a specific virus from a catalog of more than 160 human pathogens, including the COVID-19 coronavirus, simultaneously in more than 1,000 samples. More...11 May 2020
![Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention) Image: Salmonella are gram-negative, rod-shaped, facultative anaerobic bacteria. Newly developed sensitive and specific assays are able to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens (Photo courtesy of Public Health Image Library, [U.S.] Centers for Disease Control and Prevention)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2020-05-07/GMS-062B.jpg)
A Series of Sensitive and Specific DNA-Based Assays Detects and Differentiates Salmonella Serotypes
A team of Australian researchers developed a series of sensitive and specific assays to detect and identify different serotypes (serovars) of Salmonella, a common cause of bacterial foodborne disease worldwide. More...07 May 2020
In Other News
Targeted Next-Generation Sequencing Validated for Lysosomal Storage Disorders Diagnosis
Phosphorylated Tau Protein Blood Test Distinguishes Alzheimer’s Disease from Other Neurological Disorders
Rapid Diagnostic Sensor Detects COVID-19 Directly from Swab Extracts
Proteomic Analysis of Urinary Extracellular Vesicles for the Diagnosis of Prostate Cancer
Liquid Biopsy Assay for the Early Detection of Pancreatic Cancer
Scabies Detected by Molecular Methods in Skin Scrapings
Genetic Alterations Analyzed in Pediatric Low-Grade Glioma
Molecular Differences Discovered Among Ovarian Cancer Subgroups
Human NK Cells Identified by Single-Cell RNA Sequencing
Important Genetic Mechanism Behind Inflammatory Bowel Disease Revealed
Acetylated Tubulin Is a Biomarker for Severe Depression
Missing BAP1 Gene Associated with Immunosuppressive Molecules in Uveal Melanoma
Large Proteomics Study Identifies New Fluid Biomarkers for Diagnosis of Alzheimer’s Disease
A Non-Invasive Urine Test for Prediction of Kidney Transplant Failure
Real-Time Assay Evaluated for Two Sexually Transmitted Diseases
RT-LAMP Assay Developed for SARS-CoV-2
Genetic Risk Score Predicts Prostate Cancer Drug Response
Novel Inherited Mutation Predisposes Children to Medulloblastoma
SARS-CoV-2 Found in Sputum/Feces After Negative Pharyngeal Specimens
Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Protein Biomarker Is Early Predictor of Likelihood of Developing Liver Disease
Liquid Biopsy Lung Cancer Screening Method Developed
Circulating RNA Biomarker Predicts Likelihood of Developing Alzheimer’s Disease
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.