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Clinical Chemistry

Image: Altered serum bile acid profile in fibromyalgia is associated with specific gut microbiome changes and symptom severity (Photo courtesy of Blood Tests in London)

Bile Acid Profile in Severe Fibromyalgia Associated with Microbiome Changes

Fibromyalgia (FM) is a medical condition defined by the presence of chronic widespread pain, fatigue, waking unrefreshed, cognitive symptoms, lower abdominal pain or cramps, and depression. Other symptoms include insomnia and a general hypersensitivity. More...
01 Aug 2022
Image: The HISCL Presepsin Assay Kit can be used with its Automated Immunoassay System HISCL-5000/2000i/800 for immunochemistry testing (Photo courtesy of Sysmex Corporation)

Novel Presepsin Assay Evaluated Using Automated Immunoanalyzer

Biomarkers that reflect systemic responses during sepsis have been studied continuously, and there are various surrogate markers for the diagnosis of sepsis. Procalcitonin (PCT), C-reactive protein (CRP), cytokines, and chemokines have been studied extensively under the previous and revised sepsis definitions. More...
27 Jul 2022
Image: Bone Turnover Markers Including Undercarboxylated Osteocalcin Are Associated With Mortality Risk in Older Men (Photo courtesy of Blood Tests in London)

Bone Turnover Markers Associated With Mortality Risk in Older Men

Osteocalcin in its undercarboxylated form (ucOC) may influence diabetes risk; however, its relationship with all-cause and cause-specific mortality is unclear. Whether other bone turnover markers (BTMs) are associated with mortality risk differently from ucOC also remains uncertain. More...
19 Jul 2022
Image: The new BS-600M chemistry analyzer provides a complete package to help labs grow (Photo courtesy of Mindray)

Mindray’s BS-600M Chemistry Analyzer with High Sigma Level Boosts Lab Performance

Mindray (Shenzhen, China) has used the Sigma method decision chart to plot the performance of 30 biochemistry parameters on its BS-600M chemistry analyzer. Higher Sigma level system can help laboratories offer high level of quality at reduced cost and enhance clinician confidence and satisfaction. More...
18 Jul 2022
Image: A new portable medical device can monitor and enable early detection of CKD (Photo courtesy of Flinders University)

Mobile Kidney Disease Testing Device Measures Urine Albumin at POC

A new portable medical device for monitoring and early detection of chronic kidney disease (CKD), which affects an estimated 9% of the world’s population, has been shown to have potential to service rural and remote patients and communities with limited medical services. More...
06 Jul 2022
Image: Abbot Laboratories Free Thyroxine (FT4) Reagent Kit (Photo courtesy of Henry Schlein)

Thyroid Hormone Levels Linked to Liver Fibrosis in T2D

Nonalcoholic fatty liver disease (NAFLD) is a clinical pathological syndrome and one of its key characteristics is hepatic steatosis which can be caused by excessive accumulation of fat in the liver. More...
04 Jul 2022
Image: VICTOR Nivo Multimode Microplate Reader (Photo courtesy of PerkinElmer)

Simple Colorimetric Assay Determines Human Mercaptalbumin Concentration

Human serum albumin (HAS) can take on two forms, mercaptalbumin (HMA) or non-mercaptalbumin (HNA), depending on the redox status of its Cys34. The ratio of HMA and HNA is considered to be a novel biomarker of oxidative stress. More...
30 Jun 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.