Clinical Chemistry
D-Serine Clearance Evaluates Precise Measurement of Kidney Function
Evaluation of kidney function is essential in daily clinical practice. The measured glomerular filtration rate (mGFR) using exogenous inulin has been considered as the gold standard of kidney function, though this procedure is labor intensive, time consuming, and expensive. More...21 Dec 2021
Long-Term Storage Stability of Corticotropin Investigated
Corticotropin (adrenocorticotropic hormone, ACTH) is a 39-residue polypeptide tropic hormone secreted by the anterior pituitary gland following hypothalamic corticotropin-releasing hormone release. Corticotropin is notorious for its instability. More...20 Dec 2021
Circulating ACE2 Activity Predicts Mortality and Severity in COVID-19 Patients
Coronavirus disease 2019 (COVID-19) has been associated with significant morbidity and mortality worldwide in the last two years. This disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. More...16 Dec 2021
Cord Blood and Filter Paper Screening Compared for Congenital Hypothyroidism
The most prevalent predisposing factor to intellectual disability is congenital hypothyroidism (CH), which is referred to the deficiency in thyroid hormone since birth. It could be either transient or persistent deficiency. Persistent deficiency of thyroid hormone requires life-long thyroid hormone replacement. This state is known as permanent congenital hypothyroidism. More...15 Dec 2021
Serum and Plasma Choline Quantified by Clinical NMR- Analyzer
Gut microbiome-related metabolites, like trimethylamine-N-oxide (TMAO), betaine and choline are increasingly recognized as contributors to, as well as markers of, cardiometabolic and other chronic diseases. Gut microbiome mediated metabolism of phosphatidylcholine leads to the production of choline, which is then metabolized to either trimethylamine (TMA) or betaine. More...14 Dec 2021
Apolipoprotein B Singled Out as Heart Attack Risk Predictor
The selection of risk factors is based on what makes a highly significant independent contribution to predicting risk. Age, sex, smoking, systolic blood pressure and total cholesterol are well known to be important. Also, diabetes and left ventricular hypertrophy increase risk as does a previous stroke or heart attack. More...09 Dec 2021
Monocyte Distribution Width Predicts Sepsis in Critically Ill Patients
Sepsis has been reported as a major cause of increased morbidity, length of stay and mortality among patients hospitalized in Intensive Care Units (ICUs) for any cause. The survival of patients developing sepsis in the ICU is strictly related to an early diagnosis, as well as a prompt start of appropriate medical interventions. More...06 Dec 2021
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
