Clinical Chemistry


Cardiac Troponins Assessed for Acute Heart Failure
Heart failure (HF) is a clinical syndrome characterized by dyspnea, peripheral edema and fatigue. Diagnosing HF can be difficult due to overlapping symptoms with other conditions, and the phenotype of HF varies due to a broad spectrum of underlying pathophysiology. More...17 Mar 2021


Blood Biomarker Discovered for Autism Spectrum Disorder
Autism spectrum disorder (ASD), a heterogeneous neurodevelopmental disorder, is characterized by deficits in social communication and social interaction, with restricted, repetitive patterns of behavior, interests, or activities. ASD impacts at least one out of every 59 children in the USA, although this is likely an underestimation. More...11 Mar 2021

Biomarker Protein Investigated in Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatologic disease that may persist into adulthood and impact quality of life. The diagnosis is mainly based on clinical assessment rather than relying on laboratory testing. More...09 Mar 2021

Immune Response to Insulin Identifies Risk of Juvenile-Diabetes
Type 1 diabetes (T1D), also known as juvenile diabetes, is a form of diabetes in which very little or no insulin is produced by the islets of Langerhans (containing β-cells) in the pancreas. Insulin is a hormone required for the body to use blood sugar. More...08 Mar 2021

Fibrinogen to Albumin Ratio Reflects ANCA‐Associated Vasculitis Activity
Microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) belong to a group of anti-neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV). More...04 Mar 2021
In Other News
Three Automated Urine Analyzers Compared with Manual Microscopic Urinalysis
Stabilized Urinary Biogenic Amines Measured in Clinical Chemistry Laboratories
Biomarkers Evaluate Kidney Injury in Cancer Patients
Blood Test Distinguishes Epileptic Seizures From PNES
Abnormal Liver Function Test Associated with Severe SARS-CoV-2 Infection
New Control Mechanism Discovered in Innate Immune System
Reference Intervals for Liver Function Tests Established for Minors
Automated Urine Microscope Verified for Regional Laboratories
UPLC-MS/MS Method Simultaneously Determines Plasma Catecholamines and Their Metabolites
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Serum Pentosidine Levels Measured in Systemic Lupus Erythematosus
Angiopoietin-Like 2 Is a Biomarker for Diabetic Foot Patients
Gestational Lipid Profiles Associated with Adverse Cardiovascular Risk
Preliminary Predictive Criteria Identified for COVID-19 Cytokine Storm
Plasma Serglycin Levels Evaluated for Diabetic Retinopathy Diagnosis
Novel Biomarkers Predict the Development of Incident Heart Failure
Hyperglycemia and Hypoglycemia Associated with Poor Outcomes in COVID-19 Patients
Novel Biomarker Candidate for Amyotrophic Lateral Sclerosis Explored
Biomarker Evaluated for Early Detection of Congenital Heart Disease
Interstitial Fluid Sampled from Skin Using a Microneedle Patch
HDL-Cholesterol Predicts Survival in Cirrhotic Patients with Gastrointestinal Bleeding
Diagnostic Assays Evaluated for Vitamin B12 and Folate Deficiency
Kininogen-1 Protein Linked to Early Cognitive Impairment in Parkinson’s
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.