Clinical Chemistry
Abnormal Liver Function Test Associated with Severe SARS-CoV-2 Infection
COVID-19 predominantly affects the pulmonary tract causing mainly respiratory symptoms, however, involvement of other organ systems has been described, including myocarditis, acute kidney injury, neurological abnormalities and acute liver injury. More...15 Feb 2021
New Control Mechanism Discovered in Innate Immune System
Proteases are enzymes that cleave other proteins. Most often, proteases occur in cascade networks, where a particular event triggers a chain reaction in which several proteases cleave and thereby activate each other. Most well-known is probably the coagulation cascade, which causes clotting of our blood when a vessel is punctured. More...11 Feb 2021
Reference Intervals for Liver Function Tests Established for Minors
The liver is a large and complex organ that plays a central role in carbohydrate, protein, and fat metabolism. Liver function tests can reflect the degree of damage to human liver parenchyma, fibrosis, synthesis status, and coagulation function. More...04 Feb 2021
Automated Urine Microscope Verified for Regional Laboratories
Automated Urine Microscopy examines a sample of urine under a microscope. It can check cells from the urinary tract, blood cells, crystals, bacteria, parasites, and cells from tumors. This test is often used to confirm the findings of other tests or add information to a diagnosis. More...03 Feb 2021
UPLC-MS/MS Method Simultaneously Determines Plasma Catecholamines and Their Metabolites
Phaeochromocytomas and paragangliomas (PPGLs) are rare tumors of adrenal chromaffin cells or extra-adrenal paraganglia. They are difficult to diagnose because of the non-specific clinical symptoms such as hypertension, palpitations, flushing and sweating. More...27 Jan 2021
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Fanconi anemia (FA) is a complex genetic disorder frequently associated with progressive marrow failure and a strong predisposition to early malignancies, particularly squamous cell carcinomas and hepatocellular carcinomas. More...20 Jan 2021
Serum Pentosidine Levels Measured in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. More...14 Jan 2021
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In Other News
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Gestational Lipid Profiles Associated with Adverse Cardiovascular Risk
Preliminary Predictive Criteria Identified for COVID-19 Cytokine Storm
Plasma Serglycin Levels Evaluated for Diabetic Retinopathy Diagnosis
Novel Biomarkers Predict the Development of Incident Heart Failure
Hyperglycemia and Hypoglycemia Associated with Poor Outcomes in COVID-19 Patients
Novel Biomarker Candidate for Amyotrophic Lateral Sclerosis Explored
Biomarker Evaluated for Early Detection of Congenital Heart Disease
Interstitial Fluid Sampled from Skin Using a Microneedle Patch
HDL-Cholesterol Predicts Survival in Cirrhotic Patients with Gastrointestinal Bleeding
Diagnostic Assays Evaluated for Vitamin B12 and Folate Deficiency
Kininogen-1 Protein Linked to Early Cognitive Impairment in Parkinson’s
Single-Tube Multimarker Assay Estimates Preeclampsia Risk
Spot Urine Sample Evaluated for Renal Potassium Loss
Incretin Hormone Levels Linked to Arteriosclerosis
Biomarker Detects Early Alzheimer’s Disease
Elevated Fructosamine Levels Associated with Increased PJI Risk
Biomarkers Predict Whether RA Patients Will Respond to DMARDs
Breath Ammonia Biomarker Predicts Kidney Function in CKD Patients
Metabolomics Profiles Associated with Diabetic Retinopathy
High-Sensitivity C-Reactive Protein Investigated in Acute Myocardial Infarction Patients
Novel Fecal Calprotectin Test Validated in Pediatric Population
Serum Creatinine-to-Cystatin C Ratio Predicts AKI Mortality
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.