Clinical Chemistry

ALT/AST Ratio Is an Independent Risk Factor for Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is defined as a state of impaired glucose tolerance first being discovered during pregnancy. GDM increases the risk of pregnancy complications and adverse perinatal outcomes, such as pregnancy-induced hypertension, preeclampsia, abortion, premature delivery, premature ruptures of membranes, and large for gestational age infants. More...02 Feb 2022

Diagnostic Value of Serum CHI3L1 in Hepatocellular Carcinoma Explored
Primary liver cancer is the sixth diagnosed cancer and the fourth cause of cancer-related death worldwide. Hepatocellular carcinoma (HCC) is the major pathological category and comprises a 75%–85% incidence of primary liver cancer cases. More...02 Feb 2022

Proteomic Noninvasive Biomarkers Associated with Sport-Related Concussions
Sport-related concussions affect millions of individuals across the USA each year, and current techniques to diagnose and monitor them rely largely on subjective measures. Concussion can be frustratingly hard to diagnose and track. More...26 Jan 2022

HOMA2-B Assessed for Type 1 Diabetes Risk
Methods to identify individuals at highest risk for type 1 diabetes are essential for the successful implementation of disease-modifying interventions. Simple metabolic measures are needed to help stratify autoantibody-positive (Aab+) individuals who are at risk of developing type 1 diabetes. More...26 Jan 2022

Fecal Immunochemical Test for Hemoglobin Evaluated on Automated System
Colorectal cancer (CRC) is the third most common cancer in men and women and has the second most mortality rate worldwide. Most of the new CRC cases are found in patients presenting with symptoms in primary health care, such as changes in bowel habit and red blood in the feces. More...25 Jan 2022

Biochemical Parameters Compared for Diabetic Ketoacidosis Severity
Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus characterized by hyperglycemia and ketoacidosis. It can occur in both type 1 diabetes (T1DM) and type 2 (T2DM) diabetes patients under stress conditions. More...19 Jan 2022

Low Serotonin Levels Associated with Higher Nigral Iron in Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disorder characterized clinically by bradykinesia, rigidity, and/or tremor and pathologically by dopaminergic neuron loss in the substantia nigra pars compacta (SNc) and the presence of ⍺-synuclein-containing inclusions in cell bodies or neurites (Lewy pathology). More...17 Jan 2022
In Other News
Different Test Systems Analytical Performance Evaluated for Serum Creatinine
Blood Biomarker Kallikrein-8 Detects Amnestic Mild Cognitive Impairment
Nomograms Including Rapid Antigen Test Detects Primary Bladder Cancer
Near Normal Aminotransferase Levels Reported in Alcoholic Cirrhosis Patients
Serum High Sensitivity C-Reactive Protein Associated With Pre-Diabetes
Calprotectin Levels Vary When Measured in Different Matrices for COVID-19
Seasonal Temperature Impacts Patients’ Laboratory Results
D-Serine Clearance Evaluates Precise Measurement of Kidney Function
Long-Term Storage Stability of Corticotropin Investigated
Circulating ACE2 Activity Predicts Mortality and Severity in COVID-19 Patients
Cord Blood and Filter Paper Screening Compared for Congenital Hypothyroidism
Serum and Plasma Choline Quantified by Clinical NMR- Analyzer
Apolipoprotein B Singled Out as Heart Attack Risk Predictor
Monocyte Distribution Width Predicts Sepsis in Critically Ill Patients
Lipoprotein(a) Concentrations Correlate With LDL-C in Diabetic Children
Beckman Coulter Launches Automated, High-Throughput DxU Iris Urinalysis Solution in Europe
Siemens Introduces New Intelligent, Integrated IVD Solutions Virtually at EUROMEDLAB 2021
Fatty Acids Profiles Related to Biomarkers in GDM Progression
Urine Test Uses Tiny Worms to Detect Early Signs of Cancer
Vitamin D Deficiency Has Greater Risk for All-Cause Mortality
Edan Debuts Next-Gen Blood Gas & Chemistry Analyzer and Patient Monitor at MEDICA 2021
Biomarkers Associated with Major Bleeding in Patients with Atrial Fibrillation
Randox Showcases Extensive Range of Revolutionary Diagnostic Analyzers at MEDICA 2021
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.