BioResearch
Stem Cell Structure to Facilitate In Vitro Embryonic Studies
A biological construct that combines mouse embryonic stem cells and extra-embryonic trophoblast stem cells in a three-dimensional scaffold will allow in vitro studies of cellular interaction in a model that mimics a developing embryo. More...16 Mar 2017
Biomechanical Stress and Inflammation Linked Using Muscle Cells
A team of biomedical engineers used induced pluripotent stem cells from patients with Hutchinson-Gilford progeria syndrome (HGPS) to investigate the relationship between biomechanical stress and inflammation in an organ-on-a-chip device that mimicked the microenvironment of the cardiovascular system. More...15 Mar 2017
Black Carbon Nanoparticles Modify Pathogens and Affect Resistance
Nanoparticles of black carbon, one of the main components of air pollution, have been found to modify the way bacterial pathogens grow in vitro and in vivo and to significantly increase their resistance to treatment with certain antibiotics. More...14 Mar 2017
Miniaturized Gene Editing for Treatment of Macular Regeneration
A viral vector was used to insert a very small CRISPR/Cas9 gene-editing tool into mouse muscle cells or retinal pigment epithelium cells, where it induced mutations that partially cured laser damage that mimicked human chronic age-related macular degeneration. More...10 Mar 2017
Researchers Define Autoantibody-Producing Role of B-Cells in RA
The results of a recently published paper suggest that clinical trials for new rheumatoid arthritis drugs should shift from their sole focus on relieving inflammation to eliminating the B-cells that produce the anti-citrullinated protein antibodies that are the cause of the disease. More...08 Mar 2017
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In Other News
Collagen Deposition-Promoting Gene Linked to Cancer Metastasis
Metabolic Glycoengineering Introduces Targets for Guided Drug Treatment
Novel Culture Method for Activation of Cancer-Fighting T-Cells
Review Focuses on Lipid Nanoparticles as Gene Therapy Carriers
Reprogrammed Liver Cells Replace Nonfunctional Pancreatic Cells in Mouse Model
Assay Determines Suitability of Nanoparticles for In Vivo Use
Novel Method Enables Generation of Thyroid Tissue from Mouse Stem Cells
Cancer Researchers Identify Factors That Drive Melanoma Metastasis
Stem Cell Therapy is Safe: Reprogramming Does Not Increase the Rate of Mutagenesis
DNA Labels Simplify Development of Drug Delivery Nanoparticles
Enzyme Responsible for Skin Thickening Disorder Linked to Esophageal Cancer
Defects in Newly Identified Molecular Pathway Lead to Parkinson's Disease
Defects in Creatine Metabolism Linked to Inflammatory Bowel Diseases
Novel Dual-Action Drug Blocks Carcinogenic MYC Oncogene Activity
Mature Heart Muscle Cells Created from Implanted Stem Cells
Regeneration of Heart Tissue Induced by Cardiac Stem Cells
STAT3 Linked to Interferon-Induced Antiviral Response
Statins Slow Growth of Cancers with p53 Structural Mutations
Antisense Therapy Lowers Levels of Pathogenic Tau Protein in Models
New Approach to Diabetes Based on Microneedle Smart Patch Insulin Delivery
Aurintricarboxylic Acid Proposed as Basis of New Glioblastoma Treatment Plan
Nanchangmycin Prevents Zika and Related Viruses from Infecting Cells
Neurite Outgrowth Stimulated by Blocking Acetylcholine Receptor
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.