BioResearch
Crystal Structure Reveals How Neutralizing Antibody Blocks Astrovirus Infection
A team of molecular virologists used X-ray crystallography to establish how a neutralizing antibody bound to the surface of the gastroenteritis-causing astrovirus and blocked its entry into uninfected cells. More...08 Dec 2016
Antibody-Zika Virus Interaction Visualized by Cryo-Electron Microscopy
An international team of molecular virologists used advanced cryo-electron microscopy (cryoEM) techniques to visualize how the potent anti-Zika virus antibody C10 acts to prevent the virus from infecting human cells. More...07 Dec 2016
Two Classes of Fibroblasts Inhabit the Synovial Membrane in RA
Rheumatoid arthritis researchers have identified two distinct classes of synovial fibroblasts (SFs) differentiated by expression of either PDPN (podoplanin) or CD248 (endosialin), which were located within different anatomical compartments of the inflamed synovial membrane. More...07 Dec 2016
HDL Increases Macrophage Immune Response
While high-density lipoproteins (HDL) protect against atherosclerosis by inhibiting inflammation in the endothelial and smooth muscle cells that comprise the arterial wall, in immune macrophages HDL instead increases the inflammatory response. More...01 Dec 2016
Faulty Protein Interaction Disrupts Neuromuscular Junctions and Triggers ALS
Humans and mice are protected from developing amyotrophic lateral sclerosis (ALS) by the action of muscle fibers that secrete and concentrate the fibroblast growth factor binding protein 1 (FGFBP1) at neuromuscular junctions. More...01 Dec 2016
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In Other News
Study Explains How Protein Complex Mediates T-cell Development
Synthetic Hydrogel System for Growth of Intestinal Organoids
Anti-inflammatory Cytokine Prevents Development of Insulin Resistance in Model
Phosphorylation of Tau Protein Inhibits Amyloid-beta Toxicity in Alzheimer’s Model
Blocking the Acsl14 Enzyme Prevents Ferroptosis-Linked Cell Death
Lung and Tracheal Tissue Expected to Aid Respiratory Disease Research
DNA-barcode Labeled Nanoparticles Trace Drug Susceptibility
Blocking Mutant RNA Cures Huntington's Disease in Mouse Model
Mitochondrial Protein Linked to Development of Prostate Cancer
Macrophages Form Vascular Mimicry Channels to Supply Growing Tumors
Modified T-Cells Attack Tumors without Triggering Autoimmune Disease
DNA-based Zika Vaccine Demonstrates Potential in Animal Models
Experimental Monobody Drug Inhibits Most Mutated RAS Oncogenes
Biomarkers Demonstrate Potential as Indicators of HD Progression
Human Monoclonal Antibodies Prevent Congenital Transfer of Zika Virus in Mice
Modulation of Redox Environment Increases Breast Cancer Aggressiveness
Inhibition of Galactin-3 Reverses Insulin Resistance in Diabetes and Obesity Models
Proteins in Cell Nuclear Membrane Actively Influence Gene Expression
Report Describes Mechanism Underlying Genetic Eye Disease
Messenger RNA Quality Control Mechanism Explained
Researchers Describe Aggressive Breast Cancer Molecular Mechanism
Protein Identified Prevents Systemic Lupus Erythematosus
Two PARP Family Enzymes Cross-Regulate Macrophage Activation
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
