BioResearch
Artificial Stem Cells Promote Cardiac Repair in Mouse Model
A team of biomedical engineers created a novel class of artificial stem cells that mimic the function of cardiac stem cells and aid repair of damaged heart tissue without danger of adverse immune response or the possibility of tumor generation. More...05 Jan 2017
Single Mutation Causes Two Separate Neurodegenerative Diseases
Resolution of the X-ray crystallography structure of variants of TREM2 (Triggering receptor expressed on myeloid cells 2) protein revealed that mutations responsible for Nasu-Hakola disease were buried deep within the core of the folded protein, while mutations associated with Alzheimer’s disease resided on the surface of the protein. More...04 Jan 2017
Activation of Channel Proteins Slows Cancer Cell Growth and Impairs Metastatic Capability
A team of German researchers working with an aggressive breast cancer cell line showed that activation of TRPV1, a transient receptor potential channels protein, caused significant inhibition of cancer cell growth and induced apoptosis and necrosis. More...04 Jan 2017
ARID1A Mutations Linked to ATR Anti-Cancer Drug Sensitivity
A team of British cancer researchers suggested in a recent paper that screening for mutations in the ARID1A (AT-rich interactive domain-containing protein 1A) gene could aid in identifying patients with tumors sensitive to the ATR inhibitor class of anti-cancer drugs. More...03 Jan 2017
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In Other News
Phosphatidylserine Reverses Neurodegeneration in Mouse Model of Familial Dysautonomia
Protein Identified Modifies Gene Expression in Response to Mitochondrial Damage
New Drug Treatments to Target Pneumocystis Dependence on Inositol Transport
Preventing Type II Diabetes Requires Putting the Brakes on Zinc Transport Protein
Cardiomyocytes Derived from Human Pluripotent Cells Function as Pacemakers in Rodent Model
Reprogramming Therapy Reverses Signs of Aging in Mouse Progeria Model
Diet Augmented with Microgreens Lowers Cardiovascular Disease Risk
Controlling the Transient Activation of Protein Kinases in Living Cells
Combined Gene Editing and RNA Sequencing Enhances Understanding of Gene Expression
Development of Leukemia and Lymphoma Traced to Loss of T-cell Differentiation Controls
Enzyme Identified Promotes Cancer Development by Mishandling Repair of DNA Breaks
Mechanism Explains How Colon Cancer Suppressor Protein Works
Novel Approach to Bladder Cancer Chemotherapy Based on Arginine Depletion
Anti-CRISPR Proteins Increase Safety and Accuracy of Gene Editing
Development of Anti-Cancer Drugs May Overlook Compounds Useful for Humans
Shortened p53 Protein Promotes Tumor Growth by Modulating Mitochondrial Function
Enzymatic Degradation of Pyocyanin Blocks Pseudomonas Biofilm Formation
Mouse Study Identifies Molecular Mechanism behind Bacterial Meningitis
Proteasome Inhibitor Treatment Repairs Effects of Ribosomal Damage in Multiple Myeloma
Influenza Virus Proteins Block Host Cell Interference with RNA Defense Mechanism
Novel Microprotein Functions in Messenger RNA Removal Complex
New Mechanism Explains How Tumor Cells Escape Immune System Attack
Chromosomal Amplifications and Deletions Characterize Germ Line Tumors
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
