Dedicated Blood DNA Collection Tube Receives European Marketing Approval

By LabMedica International staff writers
Posted on 13 Feb 2014

Image: The PAXgene Blood DNA Tube (Photo courtesy of PreAnalytiX GmbH).

Image: The PAXgene Blood DNA Tube (Photo courtesy of PreAnalytiX GmbH).

A new collection tube for routine clinical use that was designed to preserve DNA in blood samples was recently certified for use as a diagnostic product in Europe.

The PreAnalytiX GmbH (Feldbachstrasse, Switzerland) PAXgene Blood DNA Tube provides a means for the collection of whole blood for the isolation of genomic DNA in a closed, evacuated system. Blood is collected under a standard phlebotomy protocol into an evacuated tube that contains potassium-EDTA additive. Complete isolation of DNA is carried out using manual or automated methods such as salting out precipitation, magnetic beads, or silica membrane-based technologies.

The 2.5 milliliter PAXgene Blood DNA Tube stabilizes genomic DNA with validated time and temperature parameters. The tube incorporates workflow efficiency features including a two-dimensional bar code on the label and a tube closure that clearly identifies this unique DNA collection tube.

The PAXgene tube, which recently received the European Union's CE marking IVD certification for sale in Europe was developed as part of a joint venture between Becton Dickinson and Company ((Franklin Lakes, NJ, USA) and QIAGEN (Venlo, The Netherlands).

“The validated performance data we provide to clinical scientists for the PAXgene Blood DNA Tube should reduce the chances of preanalytical error, ensuring the best quality sample for accurate IVD test performance and for blood DNA storage related to the identification of new biomarkers of disease or drug actions,” said Frank Augello, general manager of PreAnalytiX GmbH.

Related Links:
PreAnalytiX GmbH
Becton Dickinson and Company
QIAGEN

Visit expo >

Gold Member

Antipsychotic TDM Assays

Saladax Antipsychotic Assays

Collection and Transport System
PurSafe Plus®

Blood Glucose Test Strip

AutoSense Test

Gram-Negative Blood Culture Assay

LIAISON PLEX Gram-Negative Blood Culture Assay

Latest Technology News

Channels

Molecular Diagnostics

view channel

Urine Test Could Replace Painful Kidney Biopsies for Lupus Patients

Lupus is an autoimmune disorder that causes the immune system to attack the body’s own tissues and organs. Among the five million people living with lupus globally, nearly half develop lupus nephritis,... Read more

Image: The study shows that periodic ctDNA screening after surgery can help guide a decision to begin adjuvant immunotherapy (Photo courtesy of Adobe Stock)

Blood Test Guides Post-Surgical Immunotherapy for Muscle-Invasive Bladder Cancer

After surgery for muscle-invasive bladder cancer, many patients face uncertainty about whether residual cancer cells remain in their bodies. Now, a new international phase 3 study has demonstrated that... Read more

Mitochondrial DNA Mutations from Kidney Stressors Could Predict Future Organ Decline

Kidney-related diseases are alarmingly common: chronic kidney disease (CKD) affects more than one in seven U.S. adults, while about 20% of hospitalized adults are diagnosed with acute kidney injury (AKI).... Read more

Blood Test Could Predict Bariatric Surgery Outcomes in Teenagers

High blood pressure during adolescence increases the risk of lifelong cardiovascular disease, yet doctors still lack reliable tools to predict which young patients will benefit most from obesity treatments.... Read more

Hematology

view channel

Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more

Image: New research points to protecting blood during radiation therapy (Photo courtesy of 123RF)

Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments

Scientists have long focused on protecting organs near tumors during radiotherapy, but blood — a vital, circulating tissue — has largely been excluded from dose calculations. Each blood cell passing through... Read more

Image: Platelets sequester cfDNA during circulation (Murphy L. et al., Science, 2025; DOI: 10.1126/science.adp3971)

Platelets Could Improve Early and Minimally Invasive Detection of Cancer

Platelets are widely recognized for their role in blood clotting and scab formation, but they also play a crucial role in immune defense by detecting pathogens and recruiting immune cells.... Read more

Image: The microfluidic device for passive separation of platelet-rich plasma from whole blood (Photo courtesy of University of the Basque Country)

Portable and Disposable Device Obtains Platelet-Rich Plasma Without Complex Equipment

Platelet-rich plasma (PRP) plays a crucial role in regenerative medicine due to its ability to accelerate healing and repair tissue. However, obtaining PRP traditionally requires expensive centrifugation... Read more

Immunology

view channel

Molecular Microscope Diagnostic System Assesses Lung Transplant Rejection

Lung transplant recipients face a significant risk of rejection and often require routine biopsies to monitor graft health, yet assessing the same biopsy sample can be highly inconsistent among pathologists.... Read more

Blood Test Tracks Treatment Resistance in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is often diagnosed at an advanced stage because it spreads microscopically throughout the abdomen, and although initial surgery and chemotherapy can work, most... Read more

Image: The tool enables scientists to track real-time fluctuations in T cell function with unprecedented speed and precision (Photo courtesy of Shutterstock)

Luminescent Probe Measures Immune Cell Activity in Real Time

The human immune system plays a vital role in defending against disease, but its activity must be precisely monitored to ensure effective treatment in cancer therapy, autoimmune disorders, and organ transplants.... Read more

Blood-Based Immune Cell Signatures Could Guide Treatment Decisions for Critically Ill Patients

When a patient enters the emergency department in critical condition, clinicians must rapidly decide whether the patient has an infection, whether it is bacterial or viral, and whether immediate treatment... Read more

Microbiology

view channel

Image: Sugar fingerprints open new possibilities for faster and more reliable diagnosis of fungal infections (Photo courtesy of 123RF)

Fast Noninvasive Bedside Test Uses Sugar Fingerprint to Detect Fungal Infections

Candida bloodstream infections are a growing global health threat, causing an estimated 6 million cases and 3.8 million deaths annually. Hospitals are particularly vulnerable, as weakened patients after... Read more

Image: A clinical test and handheld device could quickly classify sepsis patients into two groups (Photo courtesy of Sara Moser/WashU Medicine)

Rapid Sepsis Diagnostic Device to Enable Personalized Critical Care for ICU Patients

Sepsis is a life-threatening condition that occurs when the body’s response to infection spirals out of control, damaging organs and leading to critical illness. Patients often arrive at intensive care... Read more

Image: The CD Chip (top) and The CD² Chip (bottom) (Photo courtesy of YANG Xiao)

Microfluidic Platform Assesses Neutrophil Function in Sepsis Patients

Sepsis arises from infection and immune dysregulation, with neutrophils playing a central role in its progression. However, current clinical tools are unable to both isolate these cells and assess their... Read more

New Diagnostic Method Confirms Sepsis Infections Earlier

Sepsis remains one of the most dangerous medical emergencies, often progressing rapidly and becoming fatal without timely intervention. Each hour of delayed treatment in septic shock reduces patient survival... Read more

Pathology

view channel

Image: The AI-based tool combines blood biomarkers and gene activity to more precisely track biological ageing (Photo courtesy of 123RF)

AI-Powered Method Combines Blood Data to Accurately Measure Biological Age

Chronological age tells us how many years we’ve lived, but not how quickly our bodies are ageing. Some people stay healthy well into their 80s or 90s, while others experience decline much earlier.... Read more

AI Tool Detects Cancer in Blood Samples In 10 Minutes

Detecting cancer recurrence or spread often depends on identifying rare tumor cells circulating in the bloodstream — a process known as a liquid biopsy. However, current methods rely on trained specialists... Read more

AI Pathology Analysis System Delivers Comprehensive Cancer Diagnosis

Accurate and timely cancer diagnosis is often limited by complex manual pathology workflows and lengthy turnaround times. Traditional pathology relies heavily on human interpretation, which can delay treatment... Read more

Image: AI can increase access to life-saving cervical cancer diagnostics for women (Photo courtesy of Shutterstock)

AI Improves Cervical Cancer Screening in Low-Resource Settings

Access to cervical cancer screening in low- and middle-income countries remains limited, leaving many women without early detection for this life-threatening disease. The lack of access to laboratories,... Read more

Technology

view channel

Image: The test will combine a serum with a liquid sample and apply it to the biosensor to quantify the virus at the RNA level (Photo courtesy of UCF College of Medicine)

Viral Biosensor Test Simultaneously Detects Hepatitis and HIV

Globally, over 300 million people live with Hepatitis B and C, and 40 million with HIV, according to WHO estimates. Diagnosing bloodborne viruses such as HIV and Hepatitis B and C remains challenging in... Read more

Image: The acoustofluidic device is designed for sample preparation and detection of small extracellular vesicles (Photo courtesy of Tony Jun Huang/Duke University)

Acoustofluidic Device to Transform Point-Of-Care sEV-Based Diagnostics

Rapid and sensitive detection of small extracellular vesicles (sEVs)—key biomarkers in cancer and organ health monitoring—remains challenging due to the need for multiple preprocessing steps and bulky... Read more

AI Algorithm Assesses Progressive Decline in Kidney Function

Chronic kidney disease (CKD) affects more than 700 million people worldwide and remains a major global health challenge. The condition often progresses silently, and many patients remain undiagnosed until... Read more

Image: The technology enables infected individuals to detect an infection within minutes, without requiring a laboratory, electricity, or medical personnel (Raschig, M. et al., ACS Central Science (2025). DOI: 10.1021/acscentsci.5c01179)

Taste-Based Influenza Test Could Replace Nasal Swabs with Chewing Gum

Influenza is one of the most dangerous infectious diseases worldwide, claiming around half a million lives each year. What makes it particularly insidious is that flu viruses are contagious even before... Read more

Industry

view channel

Image: This strategic merger brings together two industry leaders with complementary strengths (Photo courtesy of Advanced Instruments)

Advanced Instruments Merged Under Nova Biomedical Name

Advanced Instruments (Norwood, MA, USA) and Nova Biomedical (Waltham, MA, USA) are now officially doing business under a single, unified brand. This transformation is expected to deliver greater value... Read more

Bio-Rad and Biodesix Partner to Develop Droplet Digital PCR High Complexity Assays

Bio-Rad Laboratories (Hercules, CA, USA) and Biodesix (Louisville, CO, USA) have expanded their partnership agreement under which Biodesix will conduct the development, clinical validation, and regulatory... Read more

Hologic to be Acquired by Blackstone and TPG

Hologic (Marlborough, MA, USA) has entered into a definitive agreement to be acquired by funds managed by Blackstone (New York, NY, USA) and TPG (San Francisco, CA, USA) in a transaction valued at up to... Read more

Bio-Techne and Oxford Nanopore to Accelerate Development of Genetics Portfolio

Bio-Techne Corporation (Minneapolis, MN, USA) has expanded its agreement with Oxford Nanopore Technologies (Oxford, UK) to broaden Bio-Techne's ability to develop a portfolio of genetic products on Oxford... Read more