Pathology
Prognostic Signature Described in HPV-Positive Cell Carcinomas
Human papilloma virus (HPV) is an etiological agent of oropharyngeal squamous cell carcinoma (OPSCC). Patients with HPV+ OPSCC have high long-term survival rates: however, current radiation protocols are aggressive and can result in life-long morbidities, including difficulty swallowing, chronic dry-mouth, and altered speech. More...23 Jan 2019
Genetic Methods Rapidly Diagnoses Huntington's Disease
People with Huntington's disease suffer from jerky body movements and decreasing mental abilities. The condition usually leads to death 15 to 20 years after diagnosis. The cause of the disease is a region in the Huntingtin gene (HTT) that is absent in healthy people. More...23 Jan 2019
CD69 Biomarker Expression Predicts Atherosclerosis Risk
Atherosclerosis is a disease characterized by the accumulation of lipid deposits in the artery wall, but the disease is usually not detected until after it has caused a clinical event such as a myocardial infarction or stroke. More...22 Jan 2019
Urinary Detection Method Developed for Prostate Cancer
Prostate cancer (PCa) is one of the most common types of malignancy worldwide and is the second leading cause of cancer death among men. This cancer tends to be asymptomatic and slow growing, often with onset in young men, but usually not detected until the age of 40 to 50 years. More...22 Jan 2019
Latinos and Hispanics Prone to Kidney Disease Gene Variant
Risk variants in the apolipoprotein A-I (APOL1) gene on chromosome 22, which were first discovered in African Americans, confer a substantially increased risk of kidney disease, early-onset hypertension, and cardiovascular disease, although disease risk is modified by other genetic factors and by environmental factors. More...21 Jan 2019
New Risk Loci Identified for Polycystic Ovary Syndrome
Polycystic ovary syndrome is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. More...09 Jan 2019
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In Other News
Test Detects Protein Associated with Alzheimer’s and CTE
Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing
Rapid Next-Gen Sequencing Method Predicts Prostate Cancer Risks
Metastatic Colorectal Cancer Linked to Transcription Factors
Epigenetic Cervical Cancer Test Has Perfect Detection Rate
Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing
Neuroblastoma Molecular Analysis Leads to Prognostic Markers
Genetic and Epigenetic Features Found in Glioma Tumors
Less-Invasive Biosensor Created for Breast Cancer Diagnosis
Colorectal Cancer Risk Linked to Common and Rare Variants
Inflammatory Bowel Disease Linked to Prostate Cancer
Liquid Biopsy Identifies Advanced Lung Cancer Drivers
Circulating Tumor DNA Detects Early Melanoma Growth
Methylation-Based Liquid Biopsy Test Detects Liver Cancer
Liquid Biopsy Detects Cancer across Multiple Biomarkers
Genes Identified That Predispose People to Chronic Kidney Disease
Levels of IgA Nephropathy Associated with Disease Severity
Sensitive Tumor Detection Uses Cell-Free DNA Methylomes
Biomarker Found for Prostate Cancer Treatment Response
Genetic Basis of Childhood-Onset Cardiomyopathies Identified
Potential Brain Tumor Liquid Biopsies Developed
Genetic Test Helps Patients Avoid Unnecessary Thyroid Surgery
Chromaffin Cell Tumors Diagnosed by Plasma Panel
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.