Pathology

Pathogenic Variant Carriers Missed by Current Genetic Testing
Current guidelines recommend genetic testing for people who have a personal or family history of cancer that indicates they might be at an increased risk of harboring a pathogenic familial variant, but this approach could miss people who lack any personal or family history. More...27 Jun 2019



Novel Methylated DNA Markers Assay Detects Cancer
An estimated 56,770 people will be diagnosed with pancreatic cancer in the U.S. in 2019, and more than 45,750 will die from the disease. Pancreatic cancer is the third leading cause of cancer-related deaths in the U.S. and is expected to become the second leading cause by 2020. More...20 Jun 2019

Unhealthy Gut Promotes Spread of Breast Cancer
Most breast cancers, 65% or more, are hormone receptor positive. That means their growth is fueled by a hormone, either estrogen or progesterone. The good news is that these types of cancers are likely to respond well to hormone therapy. More...18 Jun 2019
Rare Gut Bacteria Linked to Restless Legs Syndrome
One common sleep disorder in which the microbiome may play a role is restless legs syndrome (RLS). While the pathogenesis of RLS is not fully understood, a relative state of brain iron deficiency has been described in patients with RLS and appears to induce changes in several pathways known to be involved in the disease. More...18 Jun 2019

Custom NanoString Assay Detects Bowel Cancer Subtypes
Colorectal cancer (CRC) is the fourth leading cause of cancer-related deaths worldwide. The median overall survival of metastatic (m)CRC patients with unresectable disease remains around 24 months with standard chemotherapies. More...13 Jun 2019
In Other News
Microfluidic Motility Device Indicates Likelihood of Breast Tumor Metastasis
Genomic Analysis Uncovers Differences in Liver Cancer Subtypes
CtDNA Forecasts Non-Metastatic Colorectal Cancer Recurrence
Liquid Biopsy Identifies Mutations Predicting Ovarian Cancer Treatment Response
Technology Developed to Capture Tumor Cells
Urinary Biomarkers Diagnose Serious Kidney Allergic Reaction
Blood Test Measures Effectiveness of Aggressive Cancer Treatments
Genomic Data Affects Prognosis of Advanced Prostate Cancer
Assay Stratifies Esophageal Cancer Patients for Treatment
Protein Panel Accurately Differentiates Forms of Ovarian Tumors
Prostate Cancer Severity Indicated by Location and Concentration of Syntaphilin
Clinical Validation Bolsters Liquid Biopsy Evidence Base
Breast Cancer Test Determines Most Effective Treatment
Biomarker Predicts Appropriate Immunotherapy for Cancer Patients
Oral HPV-DNA Persists after Oropharyngeal Cancer Treatment
Blood Protein Signature Reported for Diabetic Kidney Disease
Personalized Detection of ctDNA Antedates Breast Cancer
Certain Bacteria Strains Associated with Diabetic Wounds
Biomarkers of Oral Cancer Discovered
Multi-Gene Panel Testing Catches Cancer Risk Variants
Suite of Risk Variants Revealed in Hirschsprung's Disease
CRC Gut Microbial Signatures Lead to Diagnostic Tests
Genomic Classifier Test for Lung Disease Validated
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.








