Pathology

Targeted RNA Sequencing Technology Diagnoses Breast Cancer

In recent years, RNA-sequencing (RNA-seq) technology has become the standard for transcriptome analysis because of its flexibility, sensitivity, and accuracy in measuring gene expression. RNA-seq is a technology in which cDNA is derived from RNA, followed by library construction and massively parallel deep sequencing. More...
01 Oct 2019

Image: Examples of erythrocyte sedimentation rates (ESR) from normal to pathological conditions. This test indirectly measures the degree of inflammation present in the body (Photo courtesy of The Netherland Association for Hematology).

Biomarker in Adolescence Linked to Early Mortality

Inflammation is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. More...
27 Sep 2019

Image: The Quick-Ray Manual Tissue Microarrayer Set (Photo courtesy of Unitma).

Diagnostic Panel Analysis of Lung Cancer Compared

Lung cancer is the leading cause of cancer death. Non-small cell lung carcinomas are the most common type of lung cancers. They can further be divided into adenocarcinomas and squamous cell carcinomas. Accurately classifying these tumors is important to select the best treatment options for patients. More...
25 Sep 2019

Diagnostic Biomarker Expression Compared for Metastatic Tumors

Metastatic mucinous tumors pose a unique diagnostic challenge for the surgical pathologist as their morphologic and clinical characteristics are often nonspecific. The colorectum is the most common site of origin. More...
25 Sep 2019

Differences in Gut Bacteria May Predispose to Heart Attacks

Heart attacks can occur when a person has developed heart disease. A key feature of heart disease is the buildup of plaque in the arteries. Plaque is made up of fat, calcium, and other substances. More...
19 Sep 2019

$Image: A melanoma on a patient\'s skin. Most melanomas are black or brown, but they may also be skin-colored, pink, red or purple. People with chronic lymphocytic leukemia are at a higher risk for melanomas (Photo courtesy of the National Cancer Institute).$