Pathology
Pan-Cancer Study Reveals Extrachromosomal DNA Frequency
Extrachromosomal circular DNA (eccDNA) are circular DNA found in human, plant and animal cells in addition to chromosomal DNA. eccDNA originate from chromosomal DNA and can be from 50 base pairs to several mega-base pairs in length and encode regulatory elements and several full genes. More...01 Sep 2020
Cancer-Associated T Cell Receptors Evaluated for Malignancy Detection
A key goal in oncology is diagnosing cancer early, when it is more treatable. Despite decades of progress, early diagnosis of asymptomatic patients remains a major challenge. Most methods for this involve detecting cancer cells, but a different approach, focused on the body’s immune response. More...31 Aug 2020
Single-Cell Analysis Provides New Insights into Mitochondrial Diseases
Mitochondrial diseases result from failure of mitochondria, specialized compartments within cells that contain their own DNA and produce the energy needed to sustain life. Some of the most challenging mitochondrial disorders arise from mutations in mitochondrial DNA (mtDNA), a high-copy-number genome that is maternally inherited. More...24 Aug 2020
Prostate Cancer Identified By Profiling Immune Cell Subsets
With an estimated 1.8 million new cases in 2018 alone, prostate cancer is the fourth most common cancer in the world. Diagnosing the disease early increases the chances of survival, but this cancer remains difficult to detect. More...19 Aug 2020
Renal Expression of Immunomodulators in Diabetic Nephropathy
Diabetic nephropathy (DN) is a chronic microvascular complication that affects about 20% to 30% of patients with type 2 diabetes mellitus (T2DM). It is considered the leading cause of end-stage renal failure requiring renal replacement therapy. More...12 Aug 2020
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In Other News
Simple Urine Test Significantly Improves Detection of Adrenal Cancer
Somatic Evolution Identified in Non-Neoplastic IBD-Affected Colon
Digital Pathology Solution Resolves the Tissue Floater Conundrum
Pediatric Ependymoma Single-Cell Analysis Signatures Linked to Outcomes
Circulating Tumor DNA Associated with Triple-Negative Breast Cancer Recurrence
CtDNA Assay for Cancer Recurrence, MRD Applications Demonstrated
Cancer Cells Reprogram Immune Cells to Assist in Metastasis
Type 2 Diabetes Associated with Arrhythmic Daily Gut Microbe
Gene Genomic Prostate Score Test Evaluated as Prognosis Predictor
Early-Onset Preeclampsia Risk Reflected in Circulating Maternal Transcripts
Rapid Genomic Profiling of Colon Cancers Improves Therapy Selection
RNA Sequencing as Alternative to Immunohistochemistry in Cancer Diagnostics
Immune Cells Hampered Fighting Soft Tissue and Bone Sarcomas
Blood Test Could Predict Multiple Sclerosis Progression
Precision Medicine-Based Genetic Testing Developed for Prostate Cancer
Roche Advances Personalized Healthcare with Development of Image Analysis Algorithms Using Artificial Intelligence
Blood Test Predicts Prostate Cancer Treatment Response
Tumor Microbiome Appears to Vary with Cancer Type
Precision Oncology Confers Clinical Benefit in Relapsed Pediatric Cancer
Saliva-Based Assay Developed for HPV-Driven Oropharyngeal Cancer
Representative Tumor Sampling Method Lessens Molecular Analyses Bias
Germline Risk Variants Found in Prostate Cancer Patients
Non-Invasive Blood Assay Can Detect Early Colorectal Cancer
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
