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Pathology

Image: Characteristic bronchoalveolar lavage findings of diffuse alveolar hemorrhage (Photo courtesy of Peter C. Bauer, MD)

Bronchoalveolar Lavage Cell Pattern Determined for Diffuse Alveolar Hemorrhage

Diffuse alveolar hemorrhage (DAH) is a clinicopathological syndrome that describes the accumulation of intra-alveolar red blood cells originating from the alveolar capillaries. DAH can induce severe respiratory failure. More...
11 Oct 2021
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Meridian Launches New Air-Dryable qPCR Mix Enabling Direct Detection of RNA from Whole Blood Samples

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched its new Air-Dryable Direct RNA/DNA qPCR Blood Mix, an innovative master mix designed to develop room-temperature stable molecular diagnostic assays that directly amplify RNA from crude whole blood, serum, or plasma. More...
08 Oct 2021
Image: The SureSelect Target Enrichment System is a highly efficient hybrid selection technique for optimizing next-generation sequencing (Photo courtesy of Agilent Technologies)

ALPK3 Truncating Variants Cause Autosomal Dominant Hypertrophic Cardiomyopathy

In hypertrophic cardiomyopathy, heart muscles are thicker, which can make it harder for the heart to receive and pump blood. While in most cases the condition will not affect daily life, it can cause heart failure and is frequently cited as the most common cause of sudden unexpected death in young people. More...
07 Oct 2021
Image: Circulating tumor DNA (ctDNA) is found in the bloodstream and refers to DNA that comes from cancerous cells and tumors. The LiquidHALLMARK assay, a liquid biopsy test, tracks treatment-based ctDNA changes (Photo courtesy of Jonathan Bailey, National Human Genome Research Institute)

Liquid Biopsy Test Tracks Treatment-Based ctDNA Changes

Metastatic or unresectable disease is identified in approximately 20% of patients presenting with invasive urothelial cancer. In addition, up to 50% of patients will develop metastases following radical cystectomy for clinically localized disease. More...
06 Oct 2021
Image: Histopathology photomicrograph of lymphocytic esophagitis: Esophageal mucosa showing peripapillary intraepithelial lymphocytosis with basal zone hyperplasia and intercellular edema. No significant population of eosinophils or neutrophils is identified (Photo courtesy of Yusuf Kasirye, MD, et al)

CD8 T-Cell–Predominant Lymphocytic Esophagitis Associated with GERD

In patients with reflux esophagitis (RE), increased lymphocytes are often part of a mixed inflammatory infiltrate that also includes eosinophils and/or neutrophils. Less frequently, lymphocytes are the only type of inflammatory cells associated with gastroesophageal reflux disease (GERD). More...
05 Oct 2021
Image: Next Generation Phenotyping Platform from Selux (Photo courtesy of Selux Diagnostics, Inc.)

Next Generation Rapid Antibiotic Susceptibility Testing (AST) Platform Granted FDA Breakthrough Device Designation

Selux Diagnostics, Inc.’s (Boston, MA, USA) Next Generation Phenotyping (NGP) platform has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA) for positive blood culture and sterile body fluid samples. More...
05 Oct 2021
Image: Graphic representation of genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer (Photo courtesy of University of Washington School of Medicine)

Gut Bacteria Are Possible Indicators of Colon Cancer Risk

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum. Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. More...
28 Sep 2021
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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