Pathology
Mitoses Counted with Digital Pathology in Breast Phyllodes Tumors
Phyllodes tumors (PTs) are a fibroepithelial tumor composed of an epithelial and a cellular stromal component. They may be considered benign, borderline, or malignant depending on histologic features including stromal cellularity, infiltration at the tumor's edge, and mitotic activity. More...26 Nov 2020
Blood Biomarker Predicts Guillain-Barré Prognosis
Guillain-Barré syndrome (GBS) is a rare, autoimmune disorder in which a person’s own immune system damages the nerves, causing muscle weakness and sometimes paralysis. GBS can cause symptoms that last for a few weeks to several years. Most people recover fully, but some have permanent nerve damage. More...25 Nov 2020
COVID-19 Lung Damage Caused by Persistence of Abnormal Cells
Several uncertainties still relate to the involvement of other organs in COVID-19. Besides indirect multi-organ injury, a few reports have suggested the possibility of direct injury caused by viral replication in brain, heart and kidney. More...19 Nov 2020
Circulating Tumor Cell-Count Drives Therapy Choice for Breast Cancer
The choice between chemotherapy and endocrine therapy as first-line treatment for hormone receptor–positive, ERBB2 (also known as HER2)-negative metastatic breast cancer is usually based on the presence of clinical features associated with a poor prognosis. More...18 Nov 2020
Metabolomics Profiles Associated with Diabetic Retinopathy
Diabetic retinopathy (DR), like diabetic neuropathy and nephropathy, is a common complication of diabetes. It is the leading cause of loss of vision in diabetic patients. Long-standing disease, along with hyperglycemia, hyperlipidemia, hypertension, and genetic factors, is a major risk factor of diabetes retinopathy. More...16 Nov 2020
Autoantibody Timing Predicts Genetically At-Risk Children for Diabetes
While antibodies are molecules produced by the body's immune system to detect and destroy specific viruses, bacteria and other harmful substances, autoantibodies are antibodies that target a person's own healthy tissue. In the case of type 1 diabetes (T1D), a misdirected autoimmune response attacks the pancreas and gradually destroys the organ's insulin-producing beta cells. More...11 Nov 2020
Molecular Blood Test Kit Detects Gastric Cancer Early
Gastric cancer (GC) is the fifth most common cancer and the third-leading cause of cancer deaths worldwide. GC mortality is high due to late presentation. In most countries, mass screening is neither feasible nor cost-effective because such screening methods are costly and invasive, with poor compliance. More...09 Nov 2020
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In Other News
Fecal Immunochemical Test Assessed in Suspected Colorectal Cancer
Genetic Alterations Associated with Sporadic Congenital Hydrocephalus
Germline Testing After Tumor Sequencing Uncovers Clinically Actionable Variants
Novel CTC Culture Method Developed to Study Metastatic Cancer
Comprehensive Molecular Profiling Matches Pediatric Patients to Therapies
Urine-Based Liquid Biopsy Test Detects Urothelial Carcinoma
Breath Test Developed for Head and Neck Cancer Diagnosis
Lymphocytic Infiltration Explored as Biomarker for Stable Colorectal Tumors
Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma
HPV, p16 Offers Different Prognostic Clues in Oropharyngeal Cancer
Serum Thyroglobulin Assays Compared for Differentiated Thyroid Carcinoma
Epigenetic Markers Predict Type 2 Diabetes Patients Response to Metformin
New Diagnosed Anemia Linked to Crohn’s Disease Risk
Genomic Copy Number Predicts Esophageal Cancer Years Before Transformation
Circulating Tumor DNA Analysis Directs Therapy in Breast Cancer
Gut Microbiome Data Helps Routine Screening of Cardiovascular Disease
Genetics Influence Risk for Spontaneous Coronary Artery Dissection
Sequencing Could Augment Other Newborn Screening Methods
Jagged Ends of Double-Stranded DNA Characterized
Diabetes Blood Markers Linked to Alzheimer’s Disease Pathology
Saliva Test Fast Tracks Heart Attack Diagnosis
Pan-Cancer Study Reveals Extrachromosomal DNA Frequency
Adaptive Immune Cells in Ulcerative Colitis Revealed by Single-Cell Analyses
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
