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Pathology

Image: Representative GPC3 expression by IHC: Immunohistochemical staining of (A) normal skin and (B) MCC tumors for GPC3 expression. Representative images with different levels of GPC3 (and H-scores) are shown (Photo courtesy of University Hospital of Tours)

Glypican-3 Is Associated With Impaired Outcome in Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer mostly occurring in elderly patients, with increased incidence in case of immunosuppression. MCC is related to the Merkel Cell Polyomavirus (MCPyV) in 80% of cases. Immune checkpoint inhibitors provide sustained benefit in about 50% of MCC patients with advanced disease. More...
16 Aug 2022
Image: AI model reduces cost and time and increasing accuracy of cancer diagnosis (Photo courtesy of Pexels)

AI Model Accurately Shows Presence and Location of Cancer in Pathological Images

Researchers have developed a weakly supervised deep learning model that can accurately show the presence and location of cancer in pathological images based only on data where the cancer is present. More...
15 Aug 2022
Image: OS-Ultra high-performance Digital Pathology System has received CE-IVDR mark (Photo courtesy of OptraSCAN)

Digital Pathology System Provides Exceptional Image Quality Within Seconds

A high-performance digital pathology system that delivers exceptional image quality within seconds is setting new standards for laboratories. More...
02 Aug 2022
Image: Algorithm identifies protozoan Trypanosoma cruzi in photo of blood samples taken with smartphone (Photo courtesy of University of São Paulo)

AI Detects Parasite from Photos of Blood Samples Taken with Smartphone

A new study has shown that AI can be used to detect Trypanosoma cruzi, the parasite that causes Chagas disease, in images of blood samples taken with a smartphone camera and analyzed by an optical microscope. More...
02 Aug 2022
Image: A genetic link between Alzheimer’s Disease and gut disorders has been discovered (Photo courtesy of Edith Cowan University)

Genetic Link Found Between Gut Disorders and Alzheimer's Disease

Alzheimer’s disease (AD) is the most prevalent form of dementia, characterized by neurodegeneration and a progressive decline in cognitive ability. The disorder ranks as a subject of increasing global public health importance with consequences for wide-ranging social and economic adverse impacts on sufferers, their families, and the society at large. More...
02 Aug 2022
Image: p16-positive foci were defined as concurrent expression of p16 (brown) in loose collections of fibroblasts the overlying flat (A), simple cuboidal (B and C) or columnar epithelium (D) (Photo courtesy of Lawson Health Research Institute)

Digital Spatial Profiling Augments Pathology in Diagnosing Pulmonary Fibrosis

The p16 (cyclin-dependent kinase inhibitor) protein could be used to diagnose patients with the serious lung disease idiopathic pulmonary fibrosis. More...
27 Jul 2022
Image: A non-invasive digital diagnostic test could provide accurate bladder cancer diagnosis (Photo courtesy of Techcyte)

Non-Invasive Digital Diagnostic Test to Redefine Bladder Cancer Surveillance

A new collaboration is focusing on the creation of a non-invasive test that will redefine bladder cancer surveillance. More...
22 Jul 2022
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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