Pathology

Genetic Alterations Analyzed in Pediatric Low-Grade Glioma
Low grade gliomas are brain tumors that come from two different types of brain cells known as astrocytes and oligodendrocytes. They are classified as a grade 2 tumor making them the slowest growing type of glioma in adults. More...28 Apr 2020

Molecular Differences Discovered Among Ovarian Cancer Subgroups
Ovarian cancer is a highly diverse disease with a high rate of overall mortality. High-grade serous ovarian cancer (HGSC) is the most common and aggressive type of epithelial ovarian cancer, exhibiting high levels of tumor heterogeneity and variable clinical outcomes. More...28 Apr 2020

Important Genetic Mechanism Behind Inflammatory Bowel Disease Revealed
The two main forms of Inflammatory Bowel Disease (IBD), Crohn's disease and ulcerative colitis, have an important genetic component. More than 240 genetic regions have been identified that associate with IBD, more than any other pathological condition that has been studied. More...23 Apr 2020

Genetic Risk Score Predicts Prostate Cancer Drug Response
Metastatic castration-resistant prostate cancer is when the cancer has spread to parts of the body other than the prostate, and it is able to grow and spread even though drugs or other treatments to lower the amount of male sex hormones are being used to manage the cancer. More...20 Apr 2020

Novel Inherited Mutation Predisposes Children to Medulloblastoma
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts for 5% to 10% of cancer diagnoses in children. More...16 Apr 2020

Reactive Pneumocytes Identified by Distinctive Cytology
One of the most challenging and exceedingly common diagnostic dilemmas in pulmonary pathology is the distinction between reactive and neoplastic epithelial atypia. In particular, reactive pneumocytes in various infectious or inflammatory lung diseases can exhibit marked cytological atypia, which can closely resemble malignancy. More...15 Apr 2020

Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) is a lung disorder characterized by high blood pressure in the pulmonary arteries. In this instance, “idiopathic” means that the cause of the pulmonary artery hypertension is unknown. More...14 Apr 2020
In Other News
Liquid Biopsy Lung Cancer Screening Method Developed
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
EGFR Mutation Assay Cartridges Evaluated
Prognostic Values of Platelet Parameters in Gynecological Tumors Patients
Combining Biomarkers Predicts Metastasis in Medullary Thyroid Carcinoma
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Combined Biopsy Method Improves Prostate Cancer Diagnosis
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Gut Bacteria Linked to Pulmonary Artery Hypertension
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Esophageal Cancer Precursor Detected by Electronic Nose Device
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Severe Strongyloidiasis Infection Reported in Kidney Transplant Recipients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
All-Digital Histopathology Attained by Infrared-Optical Hybrid Microscopy
Several Genes Linked to Long QT Syndrome Reappraised
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Blood Test Lead to Earlier Detection of Gastrointestinal Cancers
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.