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Microbiology

Image: A transmission electron micrograph (TEM) of a number of Lassa virus virions adjacent to some cell debris (Photo courtesy of C. S. Goldsmith/CDC).

Immunoassay Developed for Lassa Fever Virus

Lassa fever is a type of viral hemorrhagic fever and is endemic in several West African countries. However, only few hospitals and laboratories in the region have the capacity to conduct molecular or serological Lassa fever diagnostics. More...
12 Apr 2018
Image: The Malaria Ag P.f test is 10 times more sensitive than current malaria rapid diagnostic tests for the detection of Plasmodium falciparum HRP-II antigen (Photo courtesy of Alere).

Ultra-Sensitive Rapid Test Evaluated for Malaria

In low prevalence regions, subpatent Plasmodium falciparum malaria infections have become an issue of increasing concern. As malaria endemic countries shift from control to elimination, the proportion of low-density P. falciparum infections increases. More...
05 Apr 2018
Image: The Xpert hepatitis C (HCV) Viral Load Assay cartridge (Photo courtesy of Cepheid).

Rapid Hepatitis C Virus POC Test Evaluated

Current hepatitis C (HCV) testing includes two clinical visits. In the first visit, clinicians test for HCV antibodies, which would confirm only that the patient has been exposed to the virus. A second visit includes testing for HCV RNA to determine the presence of active infection. More...
05 Apr 2018
Image: A histological micrograph showing endometrium with abundant plasma cells, which are diagnostic for chronic endometritis and scattered neutrophils (Photo courtesy of Nephron).

Molecular Diagnostic Tool Developed for Chronic Endometritis

Chronic endometritis is a persistent inflammation of the endometrial mucosa caused by bacterial pathogens. Although chronic endometritis can be asymptomatic, it is found in up to 40% of infertile patients and is responsible for repeated implantation failure and recurrent miscarriage. More...
04 Apr 2018
Image: A histopathology of a deep vein inflammatory infiltrate with wall dissociated by edema, observed in a skin lesion of a leprosy patient suffering an erythema nodosum leprosum episode (Photo courtesy of Oswaldo Cruz Institute).

Unusual Blood Clots Characterized in Leprosy Patients

Leprosy is a chronic infection by Mycobacterium leprae and causes body-wide symptoms, deformities, and disability. It remains a public health problem worldwide, despite the existence of antibiotic combinations that can cure it. More...
03 Apr 2018
Image: In an outbreak of Legionnaires\' disease, finding the exact source as quickly as possible is essential to preventing further infections. Investigators have now developed a rapid test that identifies Legionella pneumophila in less than one hour. The photograph shows the use of the LegioTyper-chip with the MCR microarray analysis platform (Photo courtesy of Jonas Bemetz, Technical University of Munich).

Rapid Detection of Legionella Offered for Commercial Water Systems

A rapid (approximately one hour) DNA microarray-based assay is set to replace classical culture methods for identification of Legionella bacteria in commercial water systems. More...
02 Apr 2018
Image: Two Cholkit dipsticks showing characteristic negative (left image) and positive (right image) results after 15 minutes sample run (Photo courtesy of International Centre for Diarrhoeal Disease Research).

New Dipstick Rapidly Detects Cholera in Acute Diarrhea

Cholera is an acute watery diarrheal disease caused mainly by Vibrio cholerae serogroup O1 and less commonly by V. cholerae O139. Cholera can lead to severe diarrhea and death if untreated. More...
29 Mar 2018
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.