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Microbiology

Image: A chart showing the costs associated with TB screening of healthcare workers (Image courtesy of McGill University Health Centre).

TB Screening Recommended for High-Risk Healthcare Workers Only

Routine screening for and treatment of latent tuberculosis (TB) infection has traditionally been an important part of TB prevention in Canadian and US healthcare institutions, but recent data have called into question its cost effectiveness. A new study has found that the current strategy of annual screening of is ineffectively expensive, suggesting that a switch to screening only high-risk healthcare workers is needed. More...
08 Aug 2017
Image: A new blood test has been developed to differentiate Zika virus infection from other flaviviruses (Photo courtesy of Brett Israel, University of California-Berkeley).

New Test Distinguishes Zika from Similar Viral Infections

Zika is a mosquito-borne disease and is linked to severe congenital birth defects. Assays already exist to detect Zika virus infection, but they either work only shortly after infection or are poor at differentiating Zika from other flaviviruses. More...
02 Aug 2017
Image: Immunofluorescent antibody stain showing positive Powassan virus-infected cells (Photo courtesy of Coppe Laboratories).

Powassan Virus Diagnosed in Patients with Tick-Borne Diseases

Powassan virus (POWV) lineage II, also known as deer tick virus, is an emerging tick-borne flavivirus transmitted by Ixodes scapularis ticks, which are also the primary vector for the Lyme disease pathogen Borrelia burgdorferi. More...
02 Aug 2017
Image: The Coulter LH 780 hematology analyzer (Photo courtesy of Beckman Coulter).

Antimicrobial Therapy Biomarker Enumerates Eosinophil Count Changes

Eosinopenia as a criterion of sepsis has been the subject of debate for decades and the pathophysiology of eosinopenia is related to the migration of eosinophils to the inflammatory site, presumably as a result of chemotactic substances secreted during the acute phase of inflammation. More...
01 Aug 2017
Image: The SD BIOLINE Malaria Ag P.f test is a rapid, qualitative test for the detection of histidine-rich protein II (HRP-II) antigen of Plasmodium falciparum in human whole blood (Photo courtesy of Standard Diagnostics).

Accuracy of Malaria Tests Evaluated for Febrile Children

It remains challenging to distinguish malaria from other fever causing infections, as a positive rapid diagnostic test does not always signify a true active malaria infection. Antigen persistence could increase the rate of false positive test results, leading to a wrong diagnosis in settings where other diagnostic tools are unavailable. More...
01 Aug 2017
Image: Transmission electron microscopic (TEM) depicts numbers of cytomegalovirus (CMV) virions that were present in a tissue sample (Photo courtesy of Sylvia Whitfield).

Efficacy Evaluated in Maternal Screening for Congenital CMV

Researchers have evaluated for the first time the efficacy of maternal universal screening using cytomegalovirus (CMV) IgG avidity tests for congenital CMV infection, and they have also identified problematic issues with the current maternal CMV screening methods. More...
31 Jul 2017
Image: Digitally colorized transmission electron microscopic (TEM) image of Zika virus, which is a member of the family Flaviviridae. Virus particles, here colored red, are 40 nanometers in diameter, with an outer envelope, and an inner dense core (Photo courtesy of Cynthia Goldsmith, CDC).

Antibody-Based ELISA Detects Zika with High Specificity

A recently developed human monoclonal antibody-based assay is highly effective in detecting both recent and past Zika virus (ZIKV) infections and in discriminating Zika from other flavivirus infections. More...
31 Jul 2017
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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