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Microbiology

Image: The Pegasus 4D comprehensive 2D gas chromatography with TOF MS (Photo courtesy of LECO).

Metabolite Biomarkers of Chronic Typhoid Carriage Detected

Detecting chronic carriers of typhoid is of public health relevance in areas where enteric fever is endemic, but there are no routinely used methods for prospectively identifying those carrying Salmonella in their gallbladder. More...
12 Feb 2018
Image: Parvimonas, gram-positive cocci, when found in the vagina increase the risk of HIV (Photo courtesy of Erasmus Medical Center).

Vaginal Bacteria Linked to Higher HIV Susceptibility

Disruptions of vaginal microbiota might increase women's susceptibility to human immunodeficiency virus (HIV) infection. Advances in molecular microbiology have enabled detailed examination of associations between vaginal bacteria and HIV acquisition. More...
07 Feb 2018
Image: The SteriPath Gen2 Blood Culture Collection System (Photo courtesy of Magnolia Medical Technologies).

Device Leads to Lower Blood Culture Contamination Rates

The use of a mechanical initial specimen diversion device and staff education has led to a nearly four-fold decrease in contaminated blood cultures that was sustained over 20 months. More...
07 Feb 2018
Image: The cobas CT/NG test is an in vitro nucleic acid amplification test for the qualitative detection of Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) in patient specimens (Photo courtesy of Roche Molecular Diagnostics).

New Test Allows Simultaneous Processing of Four STDs

A new test allows simultaneous processing of any combination of four separate sexually transmitted infections: Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis and Mycoplasma genitalium, from one patient sample. More...
06 Feb 2018
Image: Endometrioid ovarian carcinoma cells show nuclear staining for BRCA2 (right panel); BRCA2-negative staining in endometrioid ovarian carcinoma (left panel) (Photo courtesy of The University of Texas MD Anderson Cancer Center).

Test Identifies BRCA2 Gene Mutations for Cancers

Many variants of uncertain significance have been identified in breast cancer 2 through clinical genetic testing. VUS pose a significant clinical challenge because the contribution of these variants to cancer risk has not been determined. More...
05 Feb 2018
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Vaginal Infection Increases Risk of Fetal Membrane Rupture

Preterm pre-labor rupture of the fetal membranes precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis.
More...
05 Feb 2018
Image: T regulatory cells (also known as Tregs or Regulatory T cells) are essential cells that suppress immune responses of other cells, designed to limit excessive reactions and prevent autoimmunity. Tregs are characterized by the expression of CD4+, CD25+,and Foxp3+, while lacking CD127 (Photo courtesy of BioLegend).

Cellular Mechanism Identified for Severe Viral Hepatitis

It is known that activated immune cells of patients with viral hepatitis destroy hepatocyte, but its regulatory mechanism has not yet been described. Regulatory T cells (Tregs) inhibit activation of other immune cells and thus are important for homeostasis of the immune system. More...
29 Jan 2018
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.