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Microbiology

Image: Immunofluorescent antibody stain showing positive Powassan virus-infected cells (Photo courtesy of Coppe Laboratories).

Powassan Virus Diagnosed in Patients with Tick-Borne Diseases

Powassan virus (POWV) lineage II, also known as deer tick virus, is an emerging tick-borne flavivirus transmitted by Ixodes scapularis ticks, which are also the primary vector for the Lyme disease pathogen Borrelia burgdorferi. More...
02 Aug 2017
Image: The Coulter LH 780 hematology analyzer (Photo courtesy of Beckman Coulter).

Antimicrobial Therapy Biomarker Enumerates Eosinophil Count Changes

Eosinopenia as a criterion of sepsis has been the subject of debate for decades and the pathophysiology of eosinopenia is related to the migration of eosinophils to the inflammatory site, presumably as a result of chemotactic substances secreted during the acute phase of inflammation. More...
01 Aug 2017
Image: The SD BIOLINE Malaria Ag P.f test is a rapid, qualitative test for the detection of histidine-rich protein II (HRP-II) antigen of Plasmodium falciparum in human whole blood (Photo courtesy of Standard Diagnostics).

Accuracy of Malaria Tests Evaluated for Febrile Children

It remains challenging to distinguish malaria from other fever causing infections, as a positive rapid diagnostic test does not always signify a true active malaria infection. Antigen persistence could increase the rate of false positive test results, leading to a wrong diagnosis in settings where other diagnostic tools are unavailable. More...
01 Aug 2017
Image: Transmission electron microscopic (TEM) depicts numbers of cytomegalovirus (CMV) virions that were present in a tissue sample (Photo courtesy of Sylvia Whitfield).

Efficacy Evaluated in Maternal Screening for Congenital CMV

Researchers have evaluated for the first time the efficacy of maternal universal screening using cytomegalovirus (CMV) IgG avidity tests for congenital CMV infection, and they have also identified problematic issues with the current maternal CMV screening methods. More...
31 Jul 2017
Image: Digitally colorized transmission electron microscopic (TEM) image of Zika virus, which is a member of the family Flaviviridae. Virus particles, here colored red, are 40 nanometers in diameter, with an outer envelope, and an inner dense core (Photo courtesy of Cynthia Goldsmith, CDC).

Antibody-Based ELISA Detects Zika with High Specificity

A recently developed human monoclonal antibody-based assay is highly effective in detecting both recent and past Zika virus (ZIKV) infections and in discriminating Zika from other flavivirus infections. More...
31 Jul 2017
Image: A) Determination of the lesion for disc sampling; B) Application of the tape strip disc on the lesion; C) Even pressure applied for 20 seconds with the plunger; and D) Detaching the disc and transferred into a sterile vial for DNA isolation (Photo courtesy of the Pasteur Institute of Iran).

Novel Non-Invasive Sampling Technique Diagnoses Cutaneous Leishmaniasis

The definitive diagnosis of cutaneous leishmaniasis requires parasitological detection and it is usually based on direct detection of amastigotes in smears from lesions by microscopy and by the culturing of promastigotes from infected tissues. More...
27 Jul 2017
Image: The Magnetic Induction Cycler for real time polymerase chain reaction (Photo courtesy of Bio Molecular Systems).

RT-PCR Evaluated for Taenia Detection

Taenia solium, the pork tapeworm, and the cause of neurocysticercosis (NCC), has significant socioeconomic impacts on communities in developing countries. This disease, along with taeniasis is estimated to infect 2.5 to five million people globally. More...
27 Jul 2017
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