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Microbiology

Image: The illumigene malaria DNA amplification assay (Photo courtesy of Meridian Bioscience).

LAMP Malaria Assay Evaluated in Non-Endemic Setting

Imported malaria infections in non-endemic regions remain common due to increasing travel to endemic malaria areas and population movements. Yearly approximately 10,000 cases of imported malaria are reported, but the actual number may be as high as 30,000. More...
02 Nov 2017
Image: This transmission electron photomicrograph shows a negative-stained, Fortaleza-strain Zika virus (red) (Photo courtesy of the US National Institutes of Health).

Zika Virus Persists Longer in Cutaneous Capillary Blood

Zika virus disease is caused by a virus transmitted primarily by Aedes mosquitoes. People with Zika virus disease can have symptoms including mild fever, skin rash, conjunctivitis, muscle and joint pain, malaise or headache. More...
02 Nov 2017
Image: Dipstick tests for dengue (left) and Zika (right) accurately identify the presence of Zika virus protein in a sample (Photo courtesy of Massachusetts Institute of Technology).

Novel Immunochromatographic Method Rapidly Identifies Flaviviruses

The recent Zika virus (ZIKV) outbreak demonstrates that cost-effective clinical diagnostics are urgently needed to detect and distinguish viral infections to improve patient care. Unlike dengue virus (DENV), ZIKV infections during pregnancy correlate with severe birth defects, including microcephaly and neurological disorders. More...
01 Nov 2017
Image: The Agilent 2100 Bioanalyzer is a microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cells (Photo courtesy of CORELAB).

Viral Marker Predicts Flu Severity in Infected Patients

Influenza A viruses are the causative agents of annual epidemics, sporadic zoonotic outbreaks and occasionally pandemics. Worldwide, acute respiratory infections caused by influenza A viruses continue to be one of the main causes of acute illness and death. More...
01 Nov 2017
Image: This petri dish culture plate inoculated with Clostridium difficile has been illuminated using long-wave UV irradiation, causing the bacterial colonies to emit a fluorescent glow (Photo courtesy of James Gathany).

Infectious Diarrhea Guidelines Recommend When to Test

New culture-independent tests are much more sensitive than traditional diagnostic methods in detecting the cause of infectious diarrhea, a significant problem that leads to nearly 500,000 hospitalizations and more than 5,000 deaths in the USA every year. More...
31 Oct 2017
Image: The new Atomo HIV Self Test incorporates a unique blood collection and delivery system to further simplify the test procedure and eliminate user errors common to other test kits (Photo courtesy of Atomo Diagnostics).

Accurate HIV Self-Test Granted CE Mark

Designed for ease-of-use by untrained lay users, the rapid diagnostic self-test consists of a 3rd-generation HIV test-strip in a handheld device that incorporates a sterile safety lancet and unique blood collection and delivery system. More...
30 Oct 2017
Image: Sensitivity of the loop-mediated isothermal amplification (LAMP) assay for the detection of Clonorchis sinensis eggs in feces experimentally spiked with a known number of eggs in ten-fold serial dilutions from 10,000 eggs (lane 1) to one egg (lane 5) (Photo courtesy of Seoul National University Medical Research Center).

LAMP Assay Detects Clonorchiasis in Human Samples

Clonorchiasis is prevalent in the Far East, and a major health problem in endemic areas. Infected persons may experience, if not treated, serious complications such as bile stone formation, pyogenic cholangitis, and even cholangiocarcinoma. More...
26 Oct 2017
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