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Microbiology

Image: An arthrogram is used to help confirm periprosthetic joint infection (Photo courtesy of Dr. Robin Smithuis, MD).

Preoperative Bacteriuria Unconnected to Joint Infection

Patients who undergo elective joint replacement are traditionally screened and treated for preoperative bacteriuria in order to prevent periprosthetic joint infection (PJI), but more recently, this practice has been questioned. More...
22 Aug 2017
Image: A digitally colorized scanning electron micrograph of a T cell infected by numerous, spheroid-shaped, mustard-colored human immunodeficiency virus (HIV) particles, which can be seen attached to the cell\'s surface membrane (Photo courtesy of the US National Institute of Allergy and Infectious Diseases).

Hematologic Abnormalities Found in HIV-Infected Children

In both antiretroviral-treated and untreated individuals, different types of hematological abnormalities have been documented, the most important being pancytopenia. These changes are related with increased risk of morbidity and mortality. More...
22 Aug 2017
Image: A micrograph of esophageal candidiasis showing hyphae. Biopsy specimen stained by periodic acid-Schiff procedure (PAS stain) (Photo courtesy of Wikimedia).

Review Provides Insight into Therapeutic Interventions

A new review has outlined recommendations and a gold standard for identifying at-risk patients who are critically ill, or in receipt of organ transplants, for preventing, diagnosing and treating invasive fungal infections. It was published as part of a set of papers intended to provide new insights into the breadth of serious fungal diseases and as a call to world health bodies to prevent millions of infections each year. More...
21 Aug 2017
Image: A bioplasmonic paper-based device (BPD) for the detection of Zika virus (ZIKV) infection, via quantification of serum anti-ZIKV-nonstructural protein 1 (NS1) IgG and IgM (Photo courtesy of James Byard).

Biosensor Device Developed for Zika Diagnosis

A novel plasmonic biosensor-based detection system was developed that can diagnose recent or current Zika virus (ZIKV) infection in 15 minutes or less. More...
21 Aug 2017
Image: The VITEK MS, MALDI-TOF1 Mass Spectrometry System, an automated microbial identification system (Photo courtesy of bioMérieux).

Expanded Pathogen Identification Receives FDA Clearance

Mycobacteria, Nocardia and molds are complex organisms to identify, requiring days or weeks of specific culture conditions for appropriate growth and subsequent advanced methods for reliable identification to the species level. More...
15 Aug 2017
Image: The automated ELISA instrument (Photo courtesy of Dynex Technologies).

Three Commercial Tests for Lyme Borreliosis Evaluated

The recommended approach for the diagnosis of Lyme borreliosis consists of screening for Borrelia-specific serum antibodies with an enzyme-linked immunosorbent assay (ELISA), followed by immunoblot confirmation of equivocal or positive ELISA results. More...
15 Aug 2017
Image: In the retrospective cohort study, fluoroquinolone resistance mutation detection assay was found to be equivalent to culture-based drug sensitivity testing in predicting multidrug-resistant tuberculosis treatment outcome (Photo courtesy of Harvard Medical School).

Molecular Tests Predict TB Treatment Outcome

New molecular tests are gaining popularity as a rapid way to detect genetic mutations that render tuberculosis (TB) impervious to drugs. Yet, how well these new tests fare in gauging risk of actual drug failure has remained unclear. Researchers have now found that molecular tests that detect resistance to the fluoroquinolones class of TB drugs may be at least as good as traditional drug-sensitivity tests conducted with lab cultures. More...
14 Aug 2017
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.