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Microbiology

Image: The NextSeq 550 System brings the power of a high-throughput sequencing system to the benchtop (Photo courtesy of Illumina).

Antibiotic-Resistant Mutations Revealed by Sequencing Method

Antimicrobial resistance is on the rise and is responsible for millions of deaths every year. Bacterial populations consistently and rapidly overcome the challenge imposed by the use of a new antibiotic. More...
11 Oct 2018
Image: The Autoscope uses deep-learning software to quantify the malaria parasites in a sample (Photo courtesy of Intellectual Ventures).

Automated Microscopy Compared for Routine Malaria Diagnosis

Microscopic examination of Giemsa-stained blood films remains a major form of diagnosis in malaria case management. However, as with other visualization-based diagnoses, accuracy depends on individual technician performance, making standardization difficult and reliability poor. More...
10 Oct 2018
Image: The BD BACTEC MGIT automated mycobacterial detection system is a fully automated solution for mycobacterial liquid culture and susceptibility testing (Photo courtesy of Becton Dickinson).

TB Sequencing Could Replace Drug Susceptibility Testing

Tuberculosis (TB) is the most deadly infectious disease worldwide, causing 1.6 million deaths in 2017. Drug resistance is a particularly challenging and growing problem: as in 2017, it was estimated that 558,000 new cases of TB were resistant to rifampicin, the most effective first-line drug, and globally, just over half of patients with multi-drug resistant TB are successfully treated. More...
08 Oct 2018
Image: The MinION is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Oxford Nanopore Technologies).

Pneumonia Diagnosed by Nanopore Sequencing of Sputum

Pathogen identification in patients with community-acquired pneumonia primarily relies on culture-based techniques. Sequencing-based approaches for pathogen identification are being applied to pneumonia patients. More...
04 Oct 2018
Image: The NADAL Malaria 4 species test (RDT) (Photo courtesy of Nal von Minden).

Diagnostic Methods Compared for Detection of Malaria

The main strategy for malaria control is quick and accurate diagnosis followed by effective treatment. The early and accurate diagnosis of malaria is essential for both effective disease management and malaria surveillance. More...
04 Oct 2018
Image: The NEBNext ultra directional RNA library prep kit (Photo courtesy of New England Biolabs).

Nanopore Sequencing Enables Outbreak Field Surveillance

Outbreaks of fever of unknown origin start with nonspecific symptoms and case definition is only slowly developed and adapted, therefore, identifying the causative agent is crucial to ensure suitable treatment and control measures. More...
03 Oct 2018

Standalone HPV Testing Recommended for Cervical Cancer Screening

The number of deaths from cervical cancer in the USA has decreased substantially since the implementation of widespread cervical cancer screening and has declined from 2.8 to 2.3 deaths per 100,000 women from 2000 to 2015. More...
02 Oct 2018
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.