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Microbiology

Image: The Vitros 350 clinical chemistry system (Photo courtesy of Ortho Clinical Diagnostic).

Ammonia Predicts Prognosis in Hepatitis B Virus‐Related Liver Failure

Acute‐on‐chronic liver failure (ACLF) is the rapid deterioration of liver function in chronic liver disease often associated with the development of serious complications such as hepatorenal syndrome and hepatic encephalopathy within a short period of time. More...
24 Sep 2020
Image: Gut Microbiome Data Helps Routine Screening of Cardiovascular Disease (Photo courtesy of Nishant Mehta PhD).

Gut Microbiome Data Helps Routine Screening of Cardiovascular Disease

Besides genetics and environmental factors, gut microbiota has emerged as a new factor influencing cardiovascular disease (CVD). Although cause-effect relationships are not clearly established, the reported associations between alterations in gut microbiota and CVD are prominent. More...
22 Sep 2020
Image: Increased MAIT and iNKT cell activation is associated with improved outcome in severe COVID-19 patients (Photo courtesy of the University of Tours).

Unconventional T Cells in COVID-19 Patients Predicts Disease Outcome

While most people infected with the SARS-CoV-2 virus experience relatively mild symptoms, some patients mount an aberrant inflammatory response that can damage the lungs and cause acute respiratory distress syndrome (ARDS), potentially resulting in the patient's death. More...
17 Sep 2020
Image: Using advanced biochemical analysis of patient serum, researchers found signatures that help predict which patients are at highest risk of dying from S. aureus bacteremia, a blood infection (Photo courtesy of University of California, San Diego)

Proteomics-Based Diagnostic Test Predicts Risk of Dying from Staphylococcus aureus Bacteremia

A diagnostic approach that integrates proteomic and metabolomic techniques enabled the identification of biomarkers that could predict which patients had the highest risk of dying from Staphylococcus aureus bacteremia. More...
14 Sep 2020
Image: Schematic diagram of the immunoassay based on proximity extension assay (PEA) technology (Photo courtesy of Olink Proteomics).

Six Biomarkers Predict Severity of COVID-19

Coronavirus disease 2019 patients admitted to the ICU have high mortality. The host response to coronavirus disease 2019 has only been partially elucidated, and prognostic biomarkers have not been identified. More...
08 Sep 2020
Image: Visualization of Loopamp Trypanosoma cruzi results by the naked eye, Tubes 1 (Negative control) and 5 were negative, but #5 was positive on qPCR with a very low DNA load (Photo courtesy of Laboratorio de Biología Molecular de la Enfermedad de Chagas).

Loop-Mediated Isothermal Amplification Kit Detects Chagas Disease

Chagas disease (CD), also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that affects about six to seven million people worldwide, mainly in endemic areas of 21 Latin American countries. More...
07 Sep 2020
Image: A mobile phone app called HandLens was designed to read and report paper strip SHERLOCK results (Photo courtesy of Anna Lachenauer, Stanford University School of Medicine)

Rapid CRISPR/Cas Assay for Diagnosis of Viral Fevers in Low-Tech Environments

Rapid diagnostic tests for Ebola and Lassa fever viruses based on the RNA-targeting CRISPR/Cas13a complex have been tested successfully under field conditions in several African countries. More...
07 Sep 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.