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Microbiology

Image: A low level of potassium (K+), known as  hypokalemia, in the blood serum in COVID-19 patients is associated with disease severity and the need for invasive mechanical ventilation (Photo courtesy of Remedy Health Media).

Hypokalemia Is Associated With COVID-19 Severity

Early studies reported various electrolyte abnormalities at admission in patients who later presented the severe form of coronavirus disease 2019 (COVID-19). Electrolyte imbalance may not only affect patient care, but could provide insights into the COVID-19 pathophysiology. More...
01 Oct 2020
Image: A field-applicable, ultrasensitive diagnostic assay specifically detects DNA and RNA sequences from all Plasmodium species in symptomatic and asymptomatic malaria, and delivers its results fast in simple reporter devices (Photo courtesy of Peter Nguyen, Harvard University)

Rapid One-Step Assay for Field-Based Detection of Asymptomatic Malaria

A novel CRISPR-based ultrasensitive assay system was able to detect the four major types of malaria-causing parasites and has been streamlined for use in locations lacking the advanced laboratory equipment and highly trained technicians required for tests such as RT-qPCR, which is used extensively for monitoring the COVID-19 pandemic. More...
29 Sep 2020

Mannose-Binding Lectin Associated with Coagulopathy in Severe COVID-19

The ongoing COVID-19 pandemic has caused significant morbidity and mortality worldwide, as well as profound effects on society. COVID-19 patients have an increased risk of thromboembolic (TE) complications, which develop despite pharmacological thromboprophylaxis. More...
24 Sep 2020
Image: The Vitros 350 clinical chemistry system (Photo courtesy of Ortho Clinical Diagnostic).

Ammonia Predicts Prognosis in Hepatitis B Virus‐Related Liver Failure

Acute‐on‐chronic liver failure (ACLF) is the rapid deterioration of liver function in chronic liver disease often associated with the development of serious complications such as hepatorenal syndrome and hepatic encephalopathy within a short period of time. More...
24 Sep 2020
Image: Gut Microbiome Data Helps Routine Screening of Cardiovascular Disease (Photo courtesy of Nishant Mehta PhD).

Gut Microbiome Data Helps Routine Screening of Cardiovascular Disease

Besides genetics and environmental factors, gut microbiota has emerged as a new factor influencing cardiovascular disease (CVD). Although cause-effect relationships are not clearly established, the reported associations between alterations in gut microbiota and CVD are prominent. More...
22 Sep 2020
Image: Increased MAIT and iNKT cell activation is associated with improved outcome in severe COVID-19 patients (Photo courtesy of the University of Tours).

Unconventional T Cells in COVID-19 Patients Predicts Disease Outcome

While most people infected with the SARS-CoV-2 virus experience relatively mild symptoms, some patients mount an aberrant inflammatory response that can damage the lungs and cause acute respiratory distress syndrome (ARDS), potentially resulting in the patient's death. More...
17 Sep 2020
Image: Using advanced biochemical analysis of patient serum, researchers found signatures that help predict which patients are at highest risk of dying from S. aureus bacteremia, a blood infection (Photo courtesy of University of California, San Diego)

Proteomics-Based Diagnostic Test Predicts Risk of Dying from Staphylococcus aureus Bacteremia

A diagnostic approach that integrates proteomic and metabolomic techniques enabled the identification of biomarkers that could predict which patients had the highest risk of dying from Staphylococcus aureus bacteremia. More...
14 Sep 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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