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Microbiology

This photomicrograph of a Gram-stained urethral smear specimen, reveals some of the histopathology in an acute case of gonococcal urethritis, caused by the Gram-negative bacterium, Neisseria gonorrhoeae.  (Image courtesy of [U.S.] Centers for Disease Control and Prevention\'s Public Health Image Library)

Diagnostic Test Identifies Resistance Mutation that Enables Use of Inexpensive, Single Dose Gonorrhea Drug

By detecting the mutated gene responsible for resistance to the drug ciprofloxacin, it is possible to identify gonorrhea patients who can be cured by a single oral dose of this drug. More...
17 Aug 2020
Graphic representation of how the urinary tract microbiome in older women exhibits host genetic and environmental influences (Photo courtesy of King\'s College London).

Host Genetic, Environmental Factors Influence Urinary Tract Microbiome

The urinary microbiome is a relatively unexplored niche that varies with gender. Urinary microbes, especially in aging populations, are associated with morbidity. Both genetic and environmental factors influence the makeup of the urinary tract microbiome of older women. More...
14 Aug 2020
Image: The Melioidosis DS assay principle: A dipstick is placed into a well containing patient serum diluted in dipstick master mix (running buffer, detection antibody and control reagent) (Photo courtesy of Medical University of Graz).

Serological Dipstick Assay Developed for Melioidosis

The Gram-negative environmental pathogen Burkholderia pseudomallei, causes the severe disease melioidosis. It is highly endemic in southeast Asia and northern Australia, but recent studies suggest that it is also present in many other parts of the world where it is severely underreported. More...
05 Aug 2020
Image: The Quantikine ELISA Human Lipocalin-2/NGAL Kit is a solid phase sandwich ELISA that quantifies human Lipocalin-2/NGAL in serum, heparin plasma, saliva, and urine (Photo courtesy of R&D Systems).

Lipocalin 2 Proposed as Biomarker for Bacterial Meningitis

Central nervous system (CNS) infections cause significant mortality and morbidity worldwide. Common CNS infections include bacterial meningitis (BM) other than tuberculosis, viral encephalitis, tuberculous meningitis (TBM) and cryptococcal meningitis, but there are more than 100 documented infectious causes of CNS infections. More...
05 Aug 2020
Image: The Multisizer 4e Coulter Counter is a highly versatile particle counting and characterization system (Photo courtesy of Beckman Coulter).

Eosinophil Count Provides Diagnostic Information for COVID-19

Early diagnosis of coronavirus disease 2019 (COVID-19) and patient isolation are important for both individual patient care and disease containment. The diagnosis is confirmed by testing for the presence of nasopharyngeal viral RNA with a polymerase chain reaction assay, which has limited availability, variable turnaround time, and a high false-negative rate. More...
29 Jul 2020
Image: An ACL TOP Hemostasis Testing System (Photo courtesy of Instrumentation Laboratory).

Endotheliopathy Assessed in COVID-19-Associated Coagulopathy

An important feature of severe acute respiratory syndrome coronavirus 2 pathogenesis is COVID-19-associated coagulopathy, characterized by increased thrombotic and microvascular complications. COVID-19 infection coagulopathy is characterized by high D-dimer and fibrinogen concentrations with minor changes in prothrombin time and platelet count. More...
23 Jul 2020
Image: The FECPAKG2 is an internet connected, image based diagnostic platform scientifically validated to conduct fecal egg count (FEC) tests (Photo courtesy of Techion).

Methods Compared Classifying Intensity of Soil-Transmitted Helminth Infections

Soil-transmitted helminths (Ascaris lumbricoides, Trichuris trichiura) and the hookworms, Necator americanus and Ancylostoma duodenale affect one quarter of the world population, and are responsible for the loss of more than three million disability-adjusted life years (DALYs). More...
23 Jul 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.