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Immunology

Image: The FACSCanto II triple-laser flow cytometer (Photo courtesy of BD Biosciences).

Recurrent Miscarriage Patients Show Activated Immune System

Recurrent loss of pregnancy is an important reproductive health issue, affecting 2% to 5% of couples. Almost half of the cases remain unexplained and are treated empirically, using progesterone supplementation, anticoagulation, and/or immunomodulatory approaches. More...
19 Mar 2019
Image: The Fecal Immunochemical Test has been shown to detect colorectal cancer up to two years earlier than colonoscopy alone (Photo courtesy of Pinnacle BioLabs).

Fecal Immunochemical Tests Performance Characterized for CRC

Many patients experience fear and anxiety before undergoing colonoscopy, which may result in negative experiences. Some doctors believe that having fecal immunochemical test (FIT) as an option might result in more people getting screened for colon cancer. More...
14 Mar 2019
Image: Immunohistochemical stain for CD137 performed on paraffin-embedded tissue sections (cytoplasmic and membranous) using monoclonal BBK-2 clone (original magnification ×400) (Photo courtesy of Peter N. Carbone, MD and Qian-Yun Zhang, MD, PhD).

Immunohistochemical Stain Facilitates cHL Diagnosis

Remarkable efforts are underway to exploit classic Hodgkin lymphoma's (cHL) complex interplay of molecular alterations, loss of B-cell programming, and dependency of tumor microenvironment. More...
11 Mar 2019
Image: The Accuri C6 compact flow cytometer (Photo courtesy of BD Biosciences).

Cervical Microbes Potentially Tied to Infections and Lesions

Nearly all cervical cancers are causally associated with human papillomavirus (HPV). The burden of HPV-associated dysplasias in sub-Saharan Africa is influenced by human immunodeficiency virus (HIV). More...
07 Mar 2019
Image: Test strips of IMMY Cryptococcal Antigen Lateral Flow Assay kit (LFA) (Photo courtesy of the Institute for Medical Research, Kuala Lumpur, Malaysia).

Lateral Flow RPA Assay Developed for Cryptococcus in CSF

The most common presentations of cryptococcosis are meningitis and meningoencephalitis. Cryptococcal meningitis (CM) is a subacute meningoencephalitis and the most common cause of adult meningitis with very high mortality rates as well as vision and hearing loss in survivors. More...
06 Mar 2019
Image: A diagram of how human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans (Photo courtesy of the University of Kiel).

Intestinal Mucosa Fungus Can Affect Lung Health

The composition of the microbiome, the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs, makes a decisive contribution to human health or disease. However, biological mechanisms that cause inflammations in the microbiome are still largely unknown. More...
04 Mar 2019
Image: A colored scanning electron micrograph (SEM) of a Helicobacter pylori bacterium (red) in the stomach (Photo courtesy of Steve Gschmeissner / SPL).

Atrophic Gastritis Prevalence Determined by Serological Evidence

Gastric cancer, among the most common cancers, is a leading cause of cancer deaths worldwide. More...
19 Feb 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.