Immunology
Invasive Pulmonary Aspergillosis Diagnosed by Molecular Test
Invasive aspergillosis (IA) is a common opportunistic fungal infection, mainly affecting patients with severe and prolonged neutropenia. Early diagnosis of invasive pulmonary aspergillosis (IPA) is notoriously difficult, but crucial for prompt treatment initiation required to improve patient outcome. More...12 Jun 2019
Mannose-Binding Lectin Associated with IgG Subclass Deficiency
Mannose-binding lectin (MBL; mannan-binding protein or lectin) is involved in innate immune defense, is produced largely by hepatocytes and is encoded by MBL2 (chromosome 10q21.1). MBL promotes killing of microorganisms by complement activation via the lectin pathway and by opsonization. More...11 Jun 2019
Novel 3D-Printed Technology Lowers Cost of ELISA
Traditional enzyme-linked immunosorbent assay (ELISA) tests are performed on plates featuring 96 micro-wells; each well works as a separate testing chamber where samples can be combined with various agents that will then react with the sample, typically by changing color. More...06 Jun 2019
Cysteine-Rich 61 Biomarker Reflects RA Disease Activity
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes progressive articular damage, functional loss, and comorbidity. Until now, the exact pathological processes involved in RA remain incompletely understood. More...05 Jun 2019
Urinary Biomarkers Diagnose Serious Kidney Allergic Reaction
Acute interstitial nephritis is a condition marked by inflammation and swelling of the renal tubules, the tiny portals in the kidneys where blood is filtered. As a result, the tubules cannot properly reabsorb water and useful organic substances, such as glucose and amino acids, or secrete waste products such as urea and creatinine into urine. More...27 May 2019
Diagnostic Process Detects Alzheimer’s Years before Symptoms Appear
Alzheimer's disease (AD) pathology is accompanied by misfolding of amyloid-β (Aβ) and tau from monomeric into β-sheet–enriched pathogenic species. This process is suggested to precede about 10 to 15 years before clinical onset of the disease. More...23 May 2019
Simple and Inexpensive Ebola Virus Disease Test Developed
Ebola and Marburg viruses can cause severe bleeding and organ failure, with fatality rates reaching 90% in some outbreaks. The diseases spread through direct contact with bodily fluids of an infected person, monkey, gorilla, chimpanzee or bat. More...21 May 2019
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In Other News
Renal Transplant Rejection Assessed by HLA Antigen Bead Assay
Blood Test May Predict Cardiovascular Disease
Immune Cell Profiling Assay Boosts Use of Mass Cytometry
Multiple Myeloma Sequences Reveal Prognostic Immunoglobulin Translocation
Rapid Test for Chlamydia Antigen Antibodies Optimized
Flow Cytometry Leukemia/Lymphoma Antibody Panel Receives Approval
Diagnostic Methods Compared for Human Granulocytic Anaplasmosis
Novel Genes and Pathways Discovered in Celiac Disease
Novel Software Reduces Variability in ELISA Biomarker Tests
Parallel Assays Developed for CSF Alzheimer's Disease Proteins
High-Res Genotyping Improves Survival for Stem Cell Transplantation
Recombinant Capture Molecule Used for Viral Disease Diagnosis
TB Interferon-Gamma Release Assay Assessed in Children
Immune Signature Drives Leukemia Relapse after Transplantation
Haptoglobin Expression Linked to Newborn Outcomes
Storage Conditions Affect Urinary Albumin and Creatinine
EBV-DNA Measured in Nasopharyngeal Carcinoma Patients
Immune Relationship to Lung Tumor Evolution Characterized
Preterm Birth Clues Identified in Cervicovaginal Microbiome
Blood Test to Diagnose Heart Attacks Can Be Misleading
Oral Bacteria Linked to More Aggressive Tumors
Urinary KIM-1 Concentration Interpreted in Detecting AKI
Efficacy Investigated for Electrochemiluminescence Immunoassay
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.