Immunology
Melatonin Levels in Parkinson’s Patients Linked to Non-Motor Symptoms
Parkinson’s disease (PD) is a complex neurodegenerative disease characterized by the loss of dopaminergic neurons in the pars compacta (SNpc), resulting in the classic motor manifestations in PD patients. The clinical diagnosis of PD mainly relies on the presence of motor symptoms as the disease progresses. More...21 Jul 2020
Immunogenomic Landscape of Hematological Malignancies Mapped
The reaction of the body's immune system against cancer can be thought of as a cycle. Cancer cells contain proteins that differ from proteins in other tissue. Their components, known as antigens, have to be presented to the T cells of the immune system by the cancer cells. More...20 Jul 2020
Clonal Hematopoiesis of Indeterminate Potential Associated with hsC-Reactive Protein
Clonal hematopoiesis (CH) occurring in normally aging subjects, initially suggested by X-chromosome inactivation studies, is caused by acquired mutations in genes recurrently mutated in hematological cancers, and in non-driver candidates. More...14 Jul 2020
Fully-Automated Calprotectin Immunoassay Validated for IBD Patients
The incidence of inflammatory bowel disease (IBD) is increasing. This chronic intestinal inflammation disorder comprises two major forms of inflammation: Crohn’s disease (CD) and ulcerative colitis (UC). Distinction between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) based on clinical symptoms is often difficult. More...13 Jul 2020
RNA Sequencing as Alternative to Immunohistochemistry in Cancer Diagnostics
The conventionally used method for cancer diagnostics relies on immunohistochemical dyeing of tumor tissue sections. It allows detecting the presence and measuring the concentration of marker proteins characterizing malignant growths. The resulting microscope images indicate whether the tumor is malignant and what its molecular type is. This information is crucial for selecting the right therapy. More...06 Jul 2020
Immune Cells Hampered Fighting Soft Tissue and Bone Sarcomas
Immunotherapies such as checkpoint inhibitors that enhance the body's natural ability to fight cancer have been only minimally successful in treating sarcomas which are rare cancers that grow in the soft tissues and bones. More...06 Jul 2020
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In Other News
Blood Test Could Predict Multiple Sclerosis Progression
Diagnostic Assay Developed for Unclassified Severe Combined Immune Deficiency
Detection Rate of Monoclonal Gammopathy of Undetermined Significance Determined
Certain Cytokines Not Associated with Severity of COVID-19 Symptoms
Presepsin Values Evaluated as Sepsis Severity Markers
Biomarkers Evaluated for Lung Disease Severity in Cystic Fibrosis
Two Serodiagnostic Tests Compared for Loiasis in Non-Endemic Area
Increasingly Efficient Serological Tests Developed with Electrochemiluminescence
Tumor Mutation and Immune Microenvironment Revealed in Colorectal Cancer
Serological Exposure Markers Developed for Vivax Malaria
Endogenous Testosterone Levels Associated with Risk of Diabetes
Cytokine Signatures of Tertian Malaria Infection Profiled During Pregnancy
Silver Nanocubes Make Point-of-Care Diagnostics Easier to Read
Initial Immune Response After Dengue Virus Infection Identified
Immune Microenvironment Changes Contribute to Early-Stage Multiple Myeloma
Immune Responses Evaluated for Tick-Borne Encephalitis
High-Throughput T Cell Profiling Technique Developed
Antibody Detection Is Critical for COVID-19 Diagnosis
Blood Biomarkers Help Diagnose Parkinson's Disease
Molecular Differences Discovered Among Ovarian Cancer Subgroups
Urea Dissociation Tests Reduces SARS-CoV-2 IgM False-Positives
Human NK Cells Identified by Single-Cell RNA Sequencing
Biomarker Panel Evaluated for Primary Hyperoxaluria Patients
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.