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Molecular Diagnostics

Image: Tumor cell populations identified using digital image analysis from a stained pathology slide, with the tumor regions detected and now colored orange (Photo courtesy of Definiens).

Biomarker Reveals Cause of Papillary Thyroid Carcinoma

The expression of the CAP-GLY domain containing linker protein 2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin.  More...
26 Oct 2014
Image: The DEPArray System for analyzing individual cells (Photo courtesy of Silicon Biosystems).

Genetic Mutation Detected in Circulating Tumor Cells

Tissue biopsies from metastatic cancer patients are invasive procedures that are frequently impossible due to the lack of accessible lesions, but a sample is required for genetic analysis.   More...
26 Oct 2014
Image: The Ion Torrent Ion AmpliSeq Cancer Primer Pool kit (Photo courtesy of Life Technologies).

Molecular Immunohistochemical Profiling Identifies Invasive Breast Carcinoma

Molecular and immunohistochemical profiling of invasive micropapillary carcinoma of the breast was used to identify potentially useful markers for targeted therapies with a focus on a specific gene mutation.   More...
23 Oct 2014
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Biomarkers Identified for Early Detection of Colon Cancer

Colorectal cancer is still one of the most frequent and deadly cancers world-wide in both women and men and the prevention of this disease is, therefore, a significant public health issue.  More...
22 Oct 2014
Image: The G-Storm GS4 Thermal Cycler (Photo courtesy of Labtech International Ltd.).

Type 2 Diabetes Caused by Low Vitamin D Disputed

Low circulating concentrations of 25-hydroxyvitamin D, a marker of vitamin D status, are associated with an increased risk of type 2 diabetes, but whether this association is causal remains equivocal.  More...
16 Oct 2014
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Genetic Data Predicts LDL Cholesterol Response to Statins

Genomic data could predict whether statins will benefit a patient or not, and this data alone can explain around 15% of patients' responses to a low density lipoprotein cholesterol lowering drugs.   More...
15 Oct 2014
Image: ECG of atrial fibrillation (top) and normal sinus rhythm (bottom). The purple arrow indicates a P wave, which is lost in atrial fibrillation (Photo courtesy of Wikimedia Commons).

Blood Test Based on Genetic Biomarkers Detects Atrial Fibrillation

Heart disease researchers have developed a DNA-based blood test that identifies individuals with atrial fibrillation and predicts likelihood of suffering ischemic stroke.  More...
15 Oct 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.