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Molecular Diagnostics

Image: A diagram of circulating tumor cells in a blood sample that can be analyzed for DNA (Photo courtesy of CellMax Life).

Liquid Biopsy Assists with Tumor Treatment Response Monitoring

Non-invasive “liquid biopsies” such as blood tests are growing in use as they help overcome problems of inherent tumor heterogeneity of cancer cells, while providing previously unavailable insight into drug-resistance. They are essential in tracking and monitoring an otherwise intractable disease. More...
19 Jan 2017
Image: The 2200 TapeStation instrument (Photo courtesy of Agilent Technologies).

Vaginal Microbes Denote Early Detection of Endometrial Cancer

Endometrial cancer triggers remain elusive, but given the typical inflammatory profile in these cases, microbes in the uterine environment are suspected to play a role in the development of this disease. More...
19 Jan 2017
Image: The NextSeq 500 Series desktop sequencing system (Photo courtesy of Illumina).

Mutational Profile of Metastatic Breast Cancers Analyzed

Breast cancer often results in poor outcomes after it has metastasized to distant organs, but, while primary breast tumors have been extensively characterized at the molecular level, metastatic lesions are poorly understood. More...
18 Jan 2017
Image: Babesia microti in a thin blood smear stained with Giemsa (Photo courtesy of Spencer S. Eccles Health Sciences Library).

Molecular Test Improves Diagnosis of Human Babesiosis

Babesia species are tick-borne apicomplexan parasites that infect erythrocytes and several species including B. microti, B. duncani, B. venatorum, B. divergens and B. divergens-like organisms can infect humans. More...
18 Jan 2017

Biomarker Signatures Predict Aging Health Quality

A panel of 19 biomarkers in the blood was utilized to create molecular signatures that are able to predict how well an individual is aging and how severe the likelihood that he or she will develop an aging-related disease. More...
17 Jan 2017

Susceptibility Genes Distinct from Severity Genes in Crohn's Disease

The group of 170 gene variants that have been linked to the development of Crohn's disease has been found to operate independently from a second group of four variants, which determines how severe the disease will be. More...
17 Jan 2017
Image: The BD LSR II flow cytometry analyzer (Photo courtesy of BD Bioscience).

Genetic Test Determines Patients Sensitivity to Cancer Drug

The identification of genetic biomarkers of synthetic lethal drug sensitivity effects provides one approach to the development of targeted cancer therapies. Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs. More...
12 Jan 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.