Lab Offers New Generation Sequencing Test for Wound Microorganisms

DNA sequencing technology underlies a new diagnostic service that claims to identify all bacteria, fungi, and parasites as well as select viruses in a wound or infected area.

The "Wound~Seq" test, which is performed on swab samples taken from the affected area, is available through Granger Diagnostics (Richmond, VA, USA). Samples collected by the doctor are sent to Granger's laboratory, and results are usually returned within 48 hours.


The Wound~Seq assay utilizes state-of-the-art DNA sequencing technology to identify all microorganisms present in the wound and does not rely on culture methods. It is the second Next-Generation Care Test in Granger Diagnostics' pipeline, following Gynecologene, a test for bacterial vaginosis that incorporates this DNA sequencing technology.

Dr. David G. Bostwick, chief medical officer at Granger Diagnostics, said, "We are excited to make available, for the first time, our clinically- significant test, Wound~Seq, that utilizes next-generation sequencing of the skin microbiome. Wounds and infections afflict millions of Americans every year, and are often perplexing to treat owing to the presence of unknown pathogens. Our new validated test provides significant actionable information that assists physicians in managing infections. Previous studies have shown that wound closure that relies on genetic-assisted testing is much more rapid, decreases pain and suffering, and results in cost savings. The promise of personalized medicine is now fulfilled."

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