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Molecular Diagnostics

Gene Related to Abnormal Brain Development Identified

Using integrative genomics of brain cells, researchers have identified a gene thought to be associated with the types of brain damage that can be caused by inflammation during premature birth, suggesting the presence of a previously unknown mechanism of brain injury. More...
13 Sep 2017
Image: The gene variant, with a single amino acid switch from alanine to threonine in the brain-expressed G-protein coupled recepter CX3CR1, causes disruption of Akt signaling (Photo courtesy of Osaka University).

Gene Mutation Increases Risk of Neurodevelopmental Disorders

Researchers have found that a rare variant of the G protein-coupled receptor CX3CR1, due to only a single amino acid substitution, may become useful in predicting increased risk for developing schizophrenia and autism. More...
12 Sep 2017

Serum Level Measurements Improve Disease Risk Prediction

Results obtained by using a commercially available uromodulin ELISA kit to analyze serum samples from individuals at risk for heart and circulatory system diseases indicated that this kidney-specific protein is a biomarker not only for kidney disease but also for cardiovascular diseases. More...
12 Sep 2017
Image: A colored scanning electron micrograph (SEM) of a lung cancer cell during cell division (Photo courtesy of the National Institutes of Health).

Early Stage Cancer CTCs Indicators of Poor Prognosis

By testing blood from a pulmonary vein near the site of a lung tumor rather than from a peripheral vein, cancer researchers found that the presence of circulating tumor cells (CTCs) in the blood during early stages of the disease was indicative of a poor prognosis for the patient. More...
12 Sep 2017
Image: The A7 Agar enables the culture, semi-quantitative enumeration and the morphological identification (solid method) of Ureaplasma urealyticum and Mycoplasma hominis (Typical “fried egg” appearance”(Photo courtesy of the ELITech Group).

Antibacterial Resistance Revealed in Women with UTIs

Nearly 20% of women aged 15-29 are diagnosed with a urinary tract infection (UTI) and antibiotic resistance prolongs UTI treatment and resistance profiles vary regionally. This regional variation is an important consideration in guiding empirical treatment selection. More...
08 Sep 2017
Image: Researchers have identified biomarkers in the blood that are a promising target for a potential new test to diagnose a recent ischemic stroke (Photo by MNT).

Molecular Blood Test Could Diagnose Ischemic Stroke

Ischemic strokes, the most common and deadliest form of stroke, are caused when the contents of plaque in a major artery break away, forming a clot and blocking blood flow to the brain. More...
07 Sep 2017
Image: The AU480 is the ideal main clinical chemistry analyzer for small- to medium-sized laboratories (Photo courtesy of Beckman Coulter).

Side Effects of BP Drugs Genetically Determined

Thiazide diuretics are one of the most widely used and effective class of medications used to treat high blood pressure, and is highly effective at preventing heart attacks and strokes in patients with hypertension. More...
07 Sep 2017
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