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Molecular Diagnostics

Image: A representation of the portable device uMEDNA for DNA amplification and detection (Photo courtesy of Harvard University).

Handheld Device Developed for DNA Amplification and Detection

A method has been developed that combines electrochemical detection with recombinase polymerase amplification (RPA) on a portable device to improve detection of genetic material from multiple tuberculosis strains. More...
23 Jan 2018

Amplification Tests Evaluated for Pelvic Inflammatory Disease

Sexually transmitted Chlamydia trachomatis (chlamydia) is the most prevalent sexually transmitted infection (STI) with an estimated 68,455,000 incident cases globally in women in 2012. Chlamydia is the subject of intensive control efforts in many high-income settings. More...
23 Jan 2018

Portable Olfactory Sensor Designed for Diagnosis of Bacteria

A portable electronic "nose" (eNose) has been designed to rapidly detect and identify the most common bacteria causing soft tissue infections. More...
22 Jan 2018
Image: The crystal structure of nucleotide-free myosin V with essential light chain (Photo courtesy of Wikimedia Commons).

Loss of Myosin Prognostic for Colorectal Cancer Recurrence

Loss of the protein Myosin Vb in colorectal cancer (CRC) patients has been identified as a strong prognostic factor for recurrence of the disease. More...
22 Jan 2018
Image: A new study suggests early diagnosis changes acute care management and that rapid whole genome sequencing improves clinical care (Photo courtesy of Scientific American).

Whole Genome Sequencing Yields Clinical Information

Among acutely ill neonatal intensive care unit (NICU) patients, rapid whole genome sequencing (WGS) offers clinically useful information and substantial cost savings in comparison to the current standard of care. More...
18 Jan 2018
Image: The HTG EdgeSeq processor, assays, and parser software facilitate analysis of gene expression profiles from a wide variety of specimen types (Photo courtesy of HTG Molecular Diagnostics).

CSF MicroRNA Levels Investigated for Prodromal HD

Huntington disease (HD) is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition). Adult-onset HD is the most common form of this disorder and the mean age of onset of HD is 35 to 44 years and the median survival time is 15 to 18 years after onset. More...
17 Jan 2018

Genetic Study Predicts Stomach Cancer Progression

Although stomach cancer is treatable if detected early, diagnosis often occurs at an advanced stage, resulting in high mortality. Intestinal metaplasia (IM) is a pre-malignant condition of the gastric mucosa associated with increased gastric cancer (GC) risk. More...
17 Jan 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.