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Molecular Diagnostics

Image: A photomicrograph showing hypertrophic decidual vasculopathy, a finding seen in gestational hypertension and pre-eclampsia (Photo courtesy of Nephron).

Risk of Preeclampsia Linked to Fetal Genes

Preeclampsia affects around 3% of births in Norway; worldwide, that number is estimated to be about 5%. For the first time, a relationship has been found between fetal genes and the risk of preeclampsia in the mother. More...
15 Sep 2017
Image: The GeneXpert MTB/RIF Ultra assay for tuberculosis; this new test is critical in allowing clinicians improved diagnostic interpretation (Photo courtesy of Cepheid).

New Diagnostic Test Improves Detection of Tuberculosis

Tuberculosis (TB) remains a global health threat despite the development of new diagnostics and antitubercular drugs. The MTB/RIF assay was developed to improve TB and rifampin resistance (RIF-R) detection. More...
14 Sep 2017

Gene Related to Abnormal Brain Development Identified

Using integrative genomics of brain cells, researchers have identified a gene thought to be associated with the types of brain damage that can be caused by inflammation during premature birth, suggesting the presence of a previously unknown mechanism of brain injury. More...
13 Sep 2017
Image: The gene variant, with a single amino acid switch from alanine to threonine in the brain-expressed G-protein coupled recepter CX3CR1, causes disruption of Akt signaling (Photo courtesy of Osaka University).

Gene Mutation Increases Risk of Neurodevelopmental Disorders

Researchers have found that a rare variant of the G protein-coupled receptor CX3CR1, due to only a single amino acid substitution, may become useful in predicting increased risk for developing schizophrenia and autism. More...
12 Sep 2017

Serum Level Measurements Improve Disease Risk Prediction

Results obtained by using a commercially available uromodulin ELISA kit to analyze serum samples from individuals at risk for heart and circulatory system diseases indicated that this kidney-specific protein is a biomarker not only for kidney disease but also for cardiovascular diseases. More...
12 Sep 2017
Image: A colored scanning electron micrograph (SEM) of a lung cancer cell during cell division (Photo courtesy of the National Institutes of Health).

Early Stage Cancer CTCs Indicators of Poor Prognosis

By testing blood from a pulmonary vein near the site of a lung tumor rather than from a peripheral vein, cancer researchers found that the presence of circulating tumor cells (CTCs) in the blood during early stages of the disease was indicative of a poor prognosis for the patient. More...
12 Sep 2017
Image: The A7 Agar enables the culture, semi-quantitative enumeration and the morphological identification (solid method) of Ureaplasma urealyticum and Mycoplasma hominis (Typical “fried egg” appearance”(Photo courtesy of the ELITech Group).

Antibacterial Resistance Revealed in Women with UTIs

Nearly 20% of women aged 15-29 are diagnosed with a urinary tract infection (UTI) and antibiotic resistance prolongs UTI treatment and resistance profiles vary regionally. This regional variation is an important consideration in guiding empirical treatment selection. More...
08 Sep 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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