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Molecular Diagnostics

$Image: An example of a TaqMan Low Density Array card; each well contains a specific miRNA forward primer, a specific miRNA TaqMan probe, and a reverse \"tail\" primer (Photo courtesy of Dana-Farber Cancer Institute).$

Molecular Blood Test Developed for Kidney Cancer

Kidney cancer is usually caught because of the symptoms a patient develops, but it is also possible for kidney cancer to be asymptomatic, with tumors growing quite large before causing pain or other noticeable problems. More...
29 Aug 2017

Image: The QuantStudio 12K Flex system is a highly flexible, comprehensive real-time PCR platform (Photo courtesy of Thermo Fisher Scientific).

Gene Expression Profiling Validated for Uveal Melanoma

Uveal melanoma is a cancer of the eye involving the iris, ciliary body, or choroid (collectively referred to as the uvea). Tumors arise from the pigment cells (melanocytes) that reside within the uvea giving color to the eye. More...
29 Aug 2017

$Image: An artist\'s concept of the circulating DNA sequencing approach for cancer detection (Photo courtesy of Victor Velculescu et al / Science Translational Medicine).$

Deep Sequencing of Circulating Tumor DNA Detects Cancers Early

A recently developed blood test utilizes targeted error correction sequencing (TEC-Seq) of circulating tumor DNA to detect early-stage cancers. More...
28 Aug 2017

Image: A ribbon diagram of human cathepsin K, colored by secondary structure (Photo courtesy of Wikimedia Commons).

Bone Peptide Measurement Predicts Fracture Risk

Measurement of the peptide fragment that results from in vivo digestion of the periostin protein by the enzyme cathepsin K in blood samples identifies subjects at high risk of bone fracture. More...
28 Aug 2017

Image: A scanning electron micrograph (SEM) of a human neutrophil ingesting methicillin resistant Staphylococcus aureus (MRSA) (Photo courtesy of US National Institute of Allergy and Infectious Diseases).

DNA Sequencing of MRSA Predicts Patient Survival

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that has become resistant to most types of antibiotics, and up to 20% of patients with invasive infections die. Although S. aureus is a common bacterium that lives on the skin, if it gets inside the body through a cut it can cause septicemia. More...
23 Aug 2017

Image: A histologic section of a colonic adenoma containing invasive carcinoma (Photo courtesy of Dr. Mauro Risio).

New Molecular Test Identifies Colorectal Cancer

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, with more than 600,000 deaths each year. Among individuals undergoing treatment for the disease, recurrence occurs in 30% to 50% of all cases. The majority of these cases present in the first two to three years following initial diagnosis and treatment. More...
23 Aug 2017

Image: A glioblastoma induced by the new gene-editing and screening technology (Photo courtesy Chen Lab, Yale University).

CRISPR Technology Identifies Cancer-Causing Genes

Researchers have identified specific gene combinations that can cause the brain cancer glioblastoma, using their newly developed modified CRISPR technology that can also pinpoint triggers and primary drivers of other types cancers. Thus the new technology could help improve diagnostics, as well as in finding more specific targets for developing more effective drugs. More...
22 Aug 2017

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.