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Molecular Diagnostics

Image: A blood smear from a patient with non-Hodgkin lymphoma showing very large lymphocytes (Photo courtesy of Venngage).

BRCA2 Mutations Linked to Pediatric Non-Hodgkin Lymphoma Risk

Inherited mutations in BRCA1 and BRCA2 genes are most typically associated with an increased risk of developing breast and ovarian cancer. BRCA2 was the third most frequently mutated gene (14 occurrences) among 3,006 survivors of childhood cancer, with the highest number observed among survivors of lymphoma. More...
09 Aug 2019
Image: A photomicrograph showing tumor-infiltrating lymphocytes in colorectal carcinoma, which are suggestive of microsatellite instability, and may be seen in Lynch syndrome (Photo courtesy of Nephron).

Mutation Study Suggests Changes to Clinical Management

Lynch syndrome (LS) results from pathogenic variants in the mismatch repair (MMR) genes and is the most common hereditary cancer syndrome, affecting an estimated 1 in 300 individuals. More...
08 Aug 2019
Image: A diagram of a normal and a nerve cell affected by amyotrophic lateral sclerosis (Photo courtesy of Mayo Clinic).

Study Shows Heritability of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease, is a specific disease that causes the death of neurons controlling voluntary muscles. More...
08 Aug 2019
Image: A scientist assembling the cartridge assay that distinguishes cancer from benign aspirates from mammographically suspicious breast lesions (Photo courtesy of Wanjun Ding).

Molecular Test Accurately Distinguishes Breast Tumors

A new laboratory test has been developed to identify chemical changes to a group of cancer-related genes that can accurately detect which breast tumors are cancerous or benign, and do it in far less time than gold-standard tests on biopsied breast tissue. More...
08 Aug 2019
Image: A diagram of the workflow of the conditional reprogramming (CR) method for collection of urine and tissue samples and establishment of primary bladder cancer cell cultures (Photo courtesy of Fudan University).

Urine Test Used to Individualize Bladder Cancer Treatment

Bladder cancer is the most common urologic cancer in China and is in the top 10 most common cause of cancer death in the USA, leading to approximately 17,000 deaths in 2018. More...
08 Aug 2019
Image: The cobas e 801 module is a high throughput immunochemistry module that performs a broad range of heterogeneous immunoassay tests (Photo courtesy of Roche Diagnostics).

Low Serum IGF1 Predicts CV Events in RA Women

Hypertension is a significant health threat and an independent predictor of cardiovascular (CV) events including coronary heart disease, stroke, heart failure, and dementia in the general population and in rheumatoid arthritis (RA). More...
06 Aug 2019
Image: The device without a smartphone (left) and with a smartphone attached (right) (Photo courtesy of Rohan Mehra - Division for Strategic Public Relations).

Smartphone-Based Device Used for Influenza Virus Detection

A simple and inexpensive smartphone-based device was able to detect influenza virus particles in clinical samples with almost 100 times greater sensitivity than commercial rapid influenza diagnostic tests. More...
05 Aug 2019
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Acusera Serum Indices Control


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.