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Molecular Diagnostics

Image: The MiSeq Sequencing platform (Photo courtesy of Illumina).

Human Pegivirus Identified in Encephalitis Patients

Human pegivirus (HPgV), was previously called hepatitis G virus or GB virus C, and is a lymphotropic virus with undefined pathology and many viruses from the family Flaviviridae, to which HPgV belongs, are neurotropic. More...
17 Oct 2018
Image: The LightCycler 480 II is a high-performance, medium- to high-throughput PCR platform (Photo courtesy of Roche).

Novel Fecal Biomarker Found for Colorectal Cancer

Colorectal cancer (CRC) is a lethal disease that has been rising in incidence during recent decades, placing an increasingly important burden on the healthcare system worldwide and gut microbial dysbiosis contributes to the development of this deadly disease. More...
17 Oct 2018
Image: The LINEAR ARRAY HPV Genotyping Test is used for the detection of 37 high- and low-risk human papillomavirus genotypes (Photo courtesy of Roche Diagnostics).

Individual HPV Types Linked to HIV Infection

Although it is known that individuals living with human immunodeficiency virus (HIV) have a higher human papilloma virus (HPV) prevalence, the impact of individual HPV types on HIV acquisition is less clear. More...
15 Oct 2018
Image: A nanopore device can contain different binding proteins. Once inside the pore, these proteins act as transducers to identify specific small molecules in a sample of body fluid (Photo courtesy of Dr. Giovanni Maglia, University of Groningen).

Detection System Used for Monitoring Small Molecules

A biological nanopore-based detection system can continuously monitor glucose and asparagine levels in microliter samples of blood, urine, saliva, or other body fluid in real-time. More...
15 Oct 2018
Image: The NextSeq 550 System brings the power of a high-throughput sequencing system to the benchtop (Photo courtesy of Illumina).

Antibiotic-Resistant Mutations Revealed by Sequencing Method

Antimicrobial resistance is on the rise and is responsible for millions of deaths every year. Bacterial populations consistently and rapidly overcome the challenge imposed by the use of a new antibiotic. More...
11 Oct 2018
Image: A scanning electron micrograph of dividing breast cancer cells (Photo courtesy of National Cancer Institute).

Disease-Associated Variants in Genes Allow Early Diagnosis

Sequencing the exomes of patients can identify breast cancer risk variants, even in patients without a family history of cancer or who otherwise would not be considered to be at an elevated risk. More...
10 Oct 2018
Image: Manhattan plot for meta-analysis (discovery) of GWAS of chronic back pain; Red line depicts genome-wide statistical significance; Blue line depicts suggestive significance (Photo courtesy of University of Washington).

New Gene Variants Associated with Chronic Back Pain

Back pain causes more years lived with disability than any other health condition worldwide. Although most adults experience a new (‘acute’) episode of back pain at some point in their lives, the societal burden of back pain is driven by the minority of individuals who fail to recover from such episodes and go on to develop persistent (‘chronic’) back pain (CBP). More...
09 Oct 2018
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