Molecular Diagnostics
Genomes of Advanced Neuroendocrine Neoplasms Unveil Subtypes
Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and genetically heterogeneous malignancies, characterized by distinct prognoses based upon primary tumor localization, functionality, grade, proliferation index and diverse outcomes to treatment. More...13 Aug 2021
Molecular Assays Compared For MRD Detection In B-ALL
B-cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy in children, and it may be associated with gene alterations that regulate B-cell development. The prognostic significance of minimal residual disease (MRD) in children with acute lymphoblastic leukemia (ALL) has been demonstrated. More...11 Aug 2021
Advanced Sequencing Techniques Determine Cancer Genome Variants in Young Patients
A recent paper described a three-platform sequencing approach, including whole genome (WGS), exome, and RNA sequencing, that was used to examine tumor and germline genomes from prospectively identified children with newly diagnosed or relapsed/refractory cancers. More...03 Aug 2021
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In Other News
ALDOA and FH4 Antibodies Associated with Cerebrovascular Disease
Highly Sensitive Genetic Test for Glaucoma Developed
Neurofilament Light Chain Levels Increase Accuracy of Neurodegenerative Disease Detection
Thombomodulin Identified as Unique Biomarker for Diagnosing Necrotizing Soft-Tissue Infections
APOE Gene Influences Alzheimer's Symptoms, Biomarkers in Down Syndrome
Preemies' Blood Type Tied to Risk for Necrotizing Enterocolitis
Optical Genome Mapping Enables Constitutional Chromosomal Aberration Detection
Serum Biomarkers Enable Tracing the Progress of COVID-19 Infections
Rectal Colonization by Klebsiella Leads to Different Risks for Bacteremia
Telomerase Reverse Transcriptase Protein Expression Evaluated for Melanomas
Metabolomic Analytical Approach Identifies Multiple Neonatal Errors of Metabolism Disorders
Targeted Locus Amplification Validated for Lymphoma
Protein Biomarker Helps Diagnose Pancreatic Cancer
Rotavirus Co-Infection with Diarrheagenic Pathogens Detected by Different Methods
Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection
Genotyping Helps Avoid Needless Bone Marrow Biopsies in African-Americans
A Novel Nanowell Array Sensor for POC Measurement of Stress Hormones
Novel Stool Biomarker Screening Tests Detect Colorectal Cancer and Inflammatory Bowel Disease
Protein Biomarker Blood Test Accurately Detects Alzheimer’s Disease
Sensitive PCR Test Predicts Treatment Response in Metastatic Head and Neck Cancers
Blood-based Liquid Biopsy Test Accurately Detects More Than Fifty Types of Cancer
Circulating Tumor DNA Following Surgery Predicts Bladder Cancer Recurrence
A Nanowire-based Liquid Biopsy Method for Detection of Tumors of the Central Nervous System
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
