Molecular Diagnostics
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
DNA mismatch repair (MMR) status is routinely assessed in colorectal and endometrial carcinoma as a method of cancer prevention, surveillance in patients with Lynch syndrome and their families, and for prognostic, predictive, and therapeutic implications. More...25 Jan 2021
Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles
Peritoneal Carcinomatosis (PC) is a late stage manifestation of several gastrointestinal malignancies including appendiceal, colorectal, and gastric cancer. In PC, tumors metastasize to and deposit on the peritoneal surface and often leave patients with only palliative treatment options. More...21 Jan 2021
Alzheimer's Disease Subtypes Proposed from Brain Gene Expression Profiles
Alzheimer’s disease (AD) is the most common form of dementia in the elderly, estimated to affect more than 5.8 million individuals in the USA and more than 50 million worldwide, with almost half of individuals aged over 75 years. More...18 Jan 2021
Common Brain Malformation Traced to Its Genetic Roots
About one in 100 children has a common brain disorder called Chiari 1 malformation, but most of the time such children grow up normally and no one suspects a problem. However about one in 10 of those children, the condition causes headaches, neck pain, hearing, vision and balance disturbances, or other neurological symptoms. More...12 Jan 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.