Molecular Diagnostics
Latinos and Hispanics Prone to Kidney Disease Gene Variant
Risk variants in the apolipoprotein A-I (APOL1) gene on chromosome 22, which were first discovered in African Americans, confer a substantially increased risk of kidney disease, early-onset hypertension, and cardiovascular disease, although disease risk is modified by other genetic factors and by environmental factors. More...21 Jan 2019
Tumor Sequencing Finds Mutations Caused by Blood Disorder
Clinical sequencing assays aim to identify somatic mutations in cancer cells for accurate diagnosis and treatment. However, most clinical-grade implementations lack patient-matched germline DNA, and supplemental analyses are needed to infer the mutational status of variants. More...15 Jan 2019
Newborn Genomic Sequencing Detects Disease Risk Factors
Genomic sequencing provides many opportunities in newborn clinical care, but the challenges of interpreting and reporting newborn genomic sequencing (nGS) results need to be addressed for its broader and effective application. More...15 Jan 2019
Tools for Meningitis Diagnostics Implemented in Resource-Limited Settings
Meningitis remains a top cause of premature death and loss of disability-adjusted life years in low-income countries. In resource-limited settings, proper laboratory diagnostics are often scarce and knowledge about national and local epidemiology is limited. More...14 Jan 2019
LAMP Test Rapidly Detects Sexually Transmitted Chlamydia
Chlamydia trachomatis is the leading cause of sexually transmitted diseases (STDs) in females and males in both developed and developing countries, with more than 110 million cases annually. C. trachomatis resists antibiotic treatment and is a cofactor in HIV transmission and human cervical cancer. More...10 Jan 2019
New Risk Loci Identified for Polycystic Ovary Syndrome
Polycystic ovary syndrome is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. More...09 Jan 2019
In Other News
Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing
Rapid Next-Gen Sequencing Method Predicts Prostate Cancer Risks
Metastatic Colorectal Cancer Linked to Transcription Factors
Epigenetic Cervical Cancer Test Has Perfect Detection Rate
Molecular Cause Found for Rare Autoimmune Disorders
Gut Microbes Differ Between Two Common Conditions
Sequencing Assay Adopted for Advanced Lung Cancer Reflex Testing
Neuroblastoma Molecular Analysis Leads to Prognostic Markers
Genetic and Epigenetic Features Found in Glioma Tumors
Tick-Borne Diseases Diagnosed with Multiplex Molecular Panel
HCV-RNA Present in Body Fluids in High Viral Load Patients
Banna Virus Detected by Reverse Transcription-Loop-Mediated Isothermal Amplification
Alzheimer's Disease Risk Alleles Profiled in Latino Populations
Genetic Marker Predicts Early Relapse in Pediatric ALL
Colorectal Cancer Risk Linked to Common and Rare Variants
Newborn Cytomegalovirus Test Cleared for Marketing
Unique Genetic Makeup of Myeloma Tumor Cells Profiled
Liquid Biopsy Identifies Advanced Lung Cancer Drivers
Metagenomic Sequencing Proposed for Respiratory Tract Infection Detection
Plasmodium vivax Isolated in Duffy Negative Individuals
MALDI-TOF MS Identifies Oomycete Causing Pythiosis
Circulating Tumor DNA Detects Early Melanoma Growth
Methylation-Based Liquid Biopsy Test Detects Liver Cancer
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.