Molecular Diagnostics

Cerebrospinal Fluid Liquid Biopsy for Diagnosis of Metastatic Breast Cancer
A liquid biopsy technique that detects cell-free tumor DNA (ctDNA) in the cerebrospinal fluid (CSF) offers the possibility for early and definitive diagnosis of leptomeningeal metastasis of breast and other cancers. More...23 Mar 2022

Novel Painless Test Massively Simplifies Diagnosis of Allergies and Predicts Success of Immunotherapy
Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear. Skin tests so far have been unpleasant, time-consuming and associated with a certain risk of triggering an allergic overreaction. Researchers have now developed a novel test that massively simplifies the diagnosis of allergies and can reliably predict the success of a therapy. More...23 Mar 2022

Genetic Overlap Found for Ovarian Cancer Subtypes and Endometriosis
A research team in Australia, the US, and the UK has delved into genetic ties between specific epithelial ovarian cancer (EOC) histotypes and endometriosis, a condition previously associated with enhanced EOC risk. More...22 Mar 2022

Personalized Tumor-Informed Assay Helps Patients Get Ahead of Cancer
Over the past several years, research has shown that minimal or molecular residual disease (MRD) monitoring can reliably identify lung cancer patients at high risk of relapse, detect post-surgical recurrence often earlier than standard imaging, assess therapy response, and potentially act as a surrogate for clinical trial endpoints. Now, a newly-available platform can help detect MRD in patients with solid tumors. More...22 Mar 2022

Worm-on-a-Chip Device Could Noninvasively Diagnose Early-Stage Cancer
Dogs can use their incredible sense of smell to sniff out various forms of cancer in human breath, blood and urine samples. Similarly, in the lab a much simpler organism, the roundworm C. elegans, wriggles its way toward cancer cells by following an odor trail. Scientists have now reported a device that uses the tiny worms to detect lung cancer cells. More...22 Mar 2022

Pediatric Cancer Sequencing Expands Relapse Treatment Options
New data has demonstrated that sequencing the tumors of relapsing pediatric cancer patients can uncover alterations linked to existing and emerging targeted therapies, potentially offering improved outcomes over standard chemotherapy. More...21 Mar 2022

In Other News
Blood Plasma Biomarkers Could Improve Diagnostic Tests for Alzheimer's Disease
Groundbreaking DNA Test Evaluates Biomarkers in 517 Cancer-Relevant Genes across 30 Types of Solid Tumors
Single Cell Characterization Acral Melanoma Identifies Novel Targets for Immunotherapy
New Test Could Help Diagnose Lyme Disease Sooner and Determine Treatment Efficacy
Expression, Microbiome Features Provide Pre-Treatment Lung Function Clues for Pediatric Patients
Next-Gen Graphene Biosensor Technology Enables Lab Quality Diagnostics of Infectious Diseases, Anytime, Anywhere
Two Circulating Biomarkers Predict Cardiovascular Disease Risk in Psoriasis Patients
Fecal Microbiome Signature Predicts Pancreatic Cancer Risk
Stem Cell Architecture Drives Myelodysplastic Syndrome Progression
Single Test for Over 50 Genetic Diseases Cuts Diagnosis from Decades to Days
Paper-Based Portable Diagnostic Platform Accurately Detects Mosquito-Borne Diseases Under Field Conditions
Low-Cost Multiplexed Electrochemical Biomarker Detection Platform to Be Commercialized in POC Diagnostics
Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases
'Fingerprint' Machine Learning Technique Identifies Different Bacteria in Seconds
Liquid Biopsy of Cerebrospinal Fluid for Diagnosis of Medulloblastoma
Single-Antigen Assays Increase Clinical Laboratory's Ability to Identify Acceptable Donors for Transplants
Prognostic Test Identifies High Risk and Low Risk Smoldering Multiple Myeloma Patients
Epigenetic Biomarker Signature Predicts the Likelihood of Premature Birth
Semiconductor Microchip Detects Prostate Cancer Markers With Ultra-High Sensitivity
Biomérieux Launches Free Mobile App to Aid Clinicians in Emergency and Critical Care Diagnostics
Mitochondrial Damage May Explain the Increased Incidence of Hypertension in Black Adults
TTMV-HPV DNA Biomarker Predicts Recurrence of Oropharynx Cancer
Two Important Cardiovascular Disease Risk Factors Operate Independently
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.







