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Molecular Diagnostics

Image: Example of gene duplication that has created a copy number variation. The chromosome now has two copies of this section of DNA, rather than one (Photo courtesy of Wikimedia Commons)

A Liquid Biopsy Approach for Predicting Likely Relapse Following Treatment of Medulloblastoma in Children

A liquid biopsy technique that determines the level of cell-free DNA in cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children being treated for the malignant brain tumor medulloblastoma. More...
02 Nov 2021
Image: The Envisia Genomic Classifier Improves Idiopathic Pulmonary Fibrosis Diagnosis (Photo courtesy of Clinical Lab Products)

Gene Expression Test Improves Idiopathic Pulmonary Fibrosis Diagnosis

Idiopathic pulmonary fibrosis (IPF) is a serious chronic disease that affects the tissue surrounding the air sacs, or alveoli, in the lungs. This condition occurs when that lung tissue becomes thick and stiff for undetermined reasons. More...
01 Nov 2021
Image: Ball-and-stick model of the cyclic adenosine monophosphate (cAMP) molecule (Photo courtesy of Wikimedia Commons)

Cyclic Adenosine Monophosphate (cAMP) May Be a Diagnostic Biomarker for Chronic Respiratory Diseases

Levels of cyclic adenosine monophosphate in the blood are higher in asthma and chronic obstructive pulmonary disease (COPD) patients and may be a diagnostic biomarker for these disorders. More...
01 Nov 2021
Image: CFX Opus Real-Time PCR System (Photo courtesy of Bio-Rad Laboratories Inc.)

Bio-Rad Launches New CFX Opus Dx Real-Time PCR Detection Systems for In Vitro Diagnostics

Bio-Rad Laboratories Inc. (Hercules, CA, USA) has launche the CFX Opus 96 Dx System and the CFX Opus 384 Dx System, real-time PCR detection systems that have been listed with the US Food and Drug Administration (FDA) for IVD testing and that meet the CE-IVD requirement for IVD use in Europe. More...
01 Nov 2021
Image: A cancer cell during cell division (Photo courtesy of [U.S.] National Institutes of Health)

New Method Promises Rapid Isolation of Biomarker-Rich Extracellular Vesicles

A new method for isolating and analyzing cancer biomarkers from extracellular vesicles present in biological fluids is based on a novel magnetic particle based liquid biopsy chip. More...
29 Oct 2021
Image: Schematic Diagram of Fabric GEM workflow that provides fast, accurate results for any clinical NGS test (Photo courtesy of Fabric Genomics)

AI-Based Technology Identifies Genetic Causes of Serious Diseases

Clinical interpretation of genetic variants in the context of the patient’s phenotype is becoming the largest component of cost and time expenditure for genome-based diagnosis of rare genetic diseases. More...
28 Oct 2021
Illustration

Meridian Launches Innovative Air-Dryable qPCR Mixes Enabling Direct Detection of DNA or RNA from Urine Samples

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched two innovative Air-Dryable qPCR Mixes that enable direct detection of DNA or RNA/DNA from urine samples. More...
28 Oct 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.