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Molecular Diagnostics

Image: Researchers have validated a new antibody test to diagnose multiple sclerosis (MS) (Photo courtesy of Mayo Clinic)

New Antibody Test Diagnoses Multiple Sclerosis in 20 Minutes

Researchers at Mayo Clinic (Rochester, MN, USA) have validated a new antibody test to diagnose multiple sclerosis (MS) that measures kappa immunoglobulin free light chains in cerebrospinal fluid. The researchers conclude the test is a valid alternative to a commonly used test to detect oligoclonal bands in cerebrospinal fluid. More...
25 Mar 2022
Image: Various kinds of extracellular vesicles (EVs) (Photo courtesy of American Physiological Society)

An Extracellular Vesicle-based Liquid Biopsy for Early Cancer Detection

An extracellular vesicle-based liquid biopsy method was shown to be a promising approach for the diagnosis of stages I and II pancreatic, ovarian, and bladder cancers. More...
24 Mar 2022
Image: Representation of a breast cancer cell (Photo courtesy of Anne Weston, Francis Crick Institute via the Wellcome Collection)

Cerebrospinal Fluid Liquid Biopsy for Diagnosis of Metastatic Breast Cancer

A liquid biopsy technique that detects cell-free tumor DNA (ctDNA) in the cerebrospinal fluid (CSF) offers the possibility for early and definitive diagnosis of leptomeningeal metastasis of breast and other cancers. More...
23 Mar 2022
Image: Novel test simplifies diagnosis of allergies (Photo courtesy of Pexels)

Novel Painless Test Massively Simplifies Diagnosis of Allergies and Predicts Success of Immunotherapy

Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear. Skin tests so far have been unpleasant, time-consuming and associated with a certain risk of triggering an allergic overreaction. Researchers have now developed a novel test that massively simplifies the diagnosis of allergies and can reliably predict the success of a therapy. More...
23 Mar 2022
Image: Genetic Overlap Found for Ovarian Cancer Subtypes and Endometriosis (Photo courtesy of University of Queensland)

Genetic Overlap Found for Ovarian Cancer Subtypes and Endometriosis

A research team in Australia, the US, and the UK has delved into genetic ties between specific epithelial ovarian cancer (EOC) histotypes and endometriosis, a condition previously associated with enhanced EOC risk. More...
22 Mar 2022
Image: A new liquid-based personalized cancer monitoring platform can help detect disease earlier (Photo courtesy of Invitae Corporation)

Personalized Tumor-Informed Assay Helps Patients Get Ahead of Cancer

Over the past several years, research has shown that minimal or molecular residual disease (MRD) monitoring can reliably identify lung cancer patients at high risk of relapse, detect post-surgical recurrence often earlier than standard imaging, assess therapy response, and potentially act as a surrogate for clinical trial endpoints. Now, a newly-available platform can help detect MRD in patients with solid tumors. More...
22 Mar 2022
Image: ‘Worm-on-a-chip’ device could someday help diagnose lung cancer (Photo courtesy of Myongji University)

Worm-on-a-Chip Device Could Noninvasively Diagnose Early-Stage Cancer

Dogs can use their incredible sense of smell to sniff out various forms of cancer in human breath, blood and urine samples. Similarly, in the lab a much simpler organism, the roundworm C. elegans, wriggles its way toward cancer cells by following an odor trail. Scientists have now reported a device that uses the tiny worms to detect lung cancer cells. More...
22 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.