Molecular Diagnostics

Single-Cell RNA-Seq Reveals Cell Type–Specific Molecular and Genetic Associations to Lupus
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with elevated prevalence in women and individuals of Asian, African, and Hispanic ancestry. SLE is a disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. More...12 Apr 2022

Lyo-Ready PCR Reagents Make Ultra-Sensitive Diagnostics Development Painless
PCR Biosystems Ltd. (London, UK) has launched the Lyo-Ready Probe 1-Step Kit, a lyophilizable 4x RT-qPCR reagent mix designed for ultra-sensitive high-throughput detection of RNA sequences. The new reagents will bring the exceptional sensitivity of the company’s liquid format 1-step RT-qPCR reagents to a freeze-dryable format. More...12 Apr 2022

Smartphone-Powered Microfluidic ‘Lab on a Strip’ Dengue Test More Powerful Than LFT Testing
Dengue fever affects an estimated 400 million people each year and dengue is a serious health challenge facing half the global population. Now, new ‘lab on a strip’ technology has shown the capability of smartphone-powered tests for dengue fever. More...11 Apr 2022

Single-Cell RNA Sequencing Identifies Mechanisms Underlying Autoimmune Diseases
Two recently published studies were designed to help understand how gene expression patterns are cell-type and context specific and can explain observed variation in immune cell function among individuals. More...11 Apr 2022

Cervicovaginal DNA Virome Alterations Associated with Genital Inflammation
Cervical cancer is one of the most common cancers among women. In 2021, more than 600,000 cases and 340,000 deaths were reported worldwide. In addition to infection with the human papillomavirus (HPV), known risk factors for cervical cancer include immunodeficiency, smoking and oral contraceptive use. More...08 Apr 2022

High-Throughput Screening Assay Identifies Drugs to Treat Resistant Prostate Cancer
Many men with prostate cancer receive hormone treatment, which works by stopping male hormones like testosterone feeding the cancer. The problem is that some cancers become resistant to hormone treatment. Now, a novel high-throughput screening assay has been designed to identify inhibitors of the androgen receptor and could be used to identify new drugs to treat resistant forms of prostate cancer. More...08 Apr 2022

Circulating Levels of Anti-Müllerian Hormone Can Identify Premenopausal Women Prior to Significant Bone Density Loss
The level of anti-Müllerian hormone (AMH) in the blood has been linked to menopause-related bone loss and may be used to identify women who are experiencing, or about to experience, bone loss related to their transition into menopause. More...07 Apr 2022
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World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies
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Blood Test to Detect Protein Biomarkers Identified Using Breast Milk Could Enable Breast Cancer Screening
Newly Identified Biomarkers Detect Subcortical Small-vessel Disease
miRNA-Based Blood Borne Diagnostic Test Holds Potential for Management of Cancer Patients
Liquid Biopsy Can Detect Recurrent Breast Cancer and Monitor Progression
Thermo Fisher Launches CE-IVD Marked NGS Instrument for Diagnostic Testing
Siemens sNfL Blood Test Predicts Risk of MS Disease Activity
Rapid Test Predicts Sepsis Soon After Infection and Before Organ Damage
NGS Panels Detect RNA and DNA Cancer Biomarkers in Single Assay
Novel System to Accelerate Development of New Diagnostic Tests
Urine Liquid Biopsy Test Detects Molecular Evidence of Prostate Cancer
BDNF Risk Variant Linked to Brain Inflammation in RRMS Patients
Blood Levels of Glial Fibrillary Acidic Protein Predict Dementia Risk in Older Mexican Americans
A Minimally Invasive PCR Test for Diagnosis of Oral Cancer
Enzyme-Based Point-of-Care Test Could Rapidly Identify Stroke Patients upon Arrival at Hospital
New Antibody Test Diagnoses Multiple Sclerosis in 20 Minutes
An Extracellular Vesicle-based Liquid Biopsy for Early Cancer Detection
Cerebrospinal Fluid Liquid Biopsy for Diagnosis of Metastatic Breast Cancer
Novel Painless Test Massively Simplifies Diagnosis of Allergies and Predicts Success of Immunotherapy
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.







