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Molecular Diagnostics

Image: Magic-Angle-Spinning (MAS) nuclear magnetic resonance (NMR) was used to establish the lung cancer predictive model. The sample (blue) is rotating with high frequency inside the main magnetic field (B0). It is tilted by the magic angle θm with respect to the direction of the magnetic field orientation (Photo courtesy of Wikimedia Commons)

Metabolomics-Based Test Detects Early-Stage Lung Cancer and Predicts Patient Survival Time

A predictive model based on alterations in blood metabolites measured by high-resolution magnetic resonance spectroscopy can detect early-stage lung cancer. More...
18 Feb 2022
Image: Positive alpha-synuclein staining of a Lewy body from a patient who had Parkinson`s disease (Photo courtesy of Wikimedia Commons)

Sensitive Protein Assay Differentiates Parkinson’s Disease from Other Synucleinopathies

A team of British researchers adapted a sensitive analytical method to evaluate the diagnostic value of a real-time quaking-induced conversion (RT-QuIC) assay for assessing disease progression, stratification, and conversion in synucleinopathies such as Parkinson’s disease. More...
18 Feb 2022
Image: HER2DX test (Photo courtesy of REVEAL GENOMICS, S.L.)

World's First Genomic Test for Personalized HER2+ Breast Cancer Treatment Could Revolutionize Precision Oncology

A new test predicts the risk of HER2+ breast cancer recurrence in newly diagnosed patients and the likelihood that they will respond to pharmacological treatment. More...
18 Feb 2022
Image: Prospera dd-cfDNA test (Photo courtesy of Pexels)

dd-cfDNA Test for Assessing Kidney Transplant Rejection Performs Strongly in Real-World Study

A large, real-world study has confirmed the strong performance of its donor-derived cell-free DNA (dd-cfDNA) test in assessing rejection for kidney transplant patients. More...
18 Feb 2022
Image: SARS-CoV-2 RNA strand (Photo courtesy of 123rf.com)

CRISPR-based Assay Platform Detects Multiple Viruses and COVID-19 Variants

A cost-effective virus and variant detection platform has been developed that can test for up to 21 viruses, including SARS-CoV-2, other coronaviruses, and both influenza strains. More...
17 Feb 2022
Image: FusionPlex Dx and LiquidPlex Dx cancer tests launched in Europe (Photo courtesy of Unsplash)

New In-Vitro Diagnostic Kits Help Patients Fight Cancer in Europe

Invitae Corporation (Boulder, CO, USA) has announced the availability of FusionPlex Dx and LiquidPlex Dx in Europe, part of its Anchored Multiplex PCR chemistry in-vitro diagnostic (IVD) products. More...
17 Feb 2022
Image: FoundationOneCDx Test (Photo courtesy of Foundation Medicine)

Personalized Molecular Monitoring Assay Uses Algorithms for Early Detection of ctDNA

A circulating tumor DNA (ctDNA) detection and molecular monitoring assay uses optimized algorithms for identifying patient-specific variants and a personalized assay design that allows for the detection of ctDNA in plasma. More...
17 Feb 2022
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