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Clinical Chemistry

Image: Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is caused by a build-up of fatty deposits and fibrous tissue on the right ventricle, the chamber of the heart that pumps blood into the lungs (Photo courtesy of National Heart Foundation of Australia)

Novel Cardiovascular Biomarker Secretoneurin Implicated in Arrhythmogenesis

Secretoneurin is a 33-amino acid peptide derived from neuroendocrine and myocardial tissue that belongs to the granin protein family. Secretoneurin may play a role in regulating processes in the myocardium, including cardiomyocyte Ca2+ handling, and has been implicated in arrhythmogenesis. More...
21 Oct 2021
Image: The association between admission HbA1c and subsequent risk of composite vascular events, including stroke, myocardial infarction, and vascular death, in patients with acute ischemic stroke and diabetes has been reported (Photo courtesy of Diabetes.co.uk)

Admission HbA1c Levels Associated with Risk of Second Stroke in Diabetics

An ischemic attack is caused by a disruption in the blood supply to part of the brain and this disruption in blood supply results in a lack of oxygen to the brain. This can cause sudden symptoms similar to a stroke, such as speech and visual disturbance, and numbness or weakness in the face, arms and legs. More...
18 Oct 2021
Image: Simoa is an ultra-sensitive immunoassay technology that allow detection of proteins and nucleic acids at lowest possible levels (Photo courtesy of Quanterix)

Plasma Amyloid-β 42/40 Assays Compared in Alzheimer Disease

Blood-based tests for brain amyloid-β (Aβ) pathology are needed for widespread implementation of Alzheimer disease (AD) biomarkers in clinical care and to facilitate patient screening and monitoring of treatment responses in clinical trials. More...
14 Oct 2021
Image: The SCIEX QTRAP 6500+ system combines triple quadrupole mass spectrometry with linear ion trap (LIT) (Photo courtesy of Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences)

Folate, Vitamin B12 Tied to GDM Risk in Early Pregnancy

Gestational diabetes mellitus (GDM) is a common medical disorder in pregnancy, estimated to affect more than 20 million pregnancies worldwide, and causes significant short- and long-term consequences to both the women and their offspring. More...
12 Oct 2021
Image: Laboratory water systems from Carolina Liquid Chemistries (Photo courtesy of Carolina Liquid Chemistries, Corp.)

Carolina Liquid Chemistries Corp. Introduces Line of Water Systems for Clinical Chemistry Analyzers

Carolina Liquid Chemistries, Corp. (CLC, Greensboro, NC, USA) has introduced a new line of laboratory water systems to the US market. The water system is offered in two models for compatibility with a variety of automated clinical analyzers. More...
07 Oct 2021
Image: The AU5800 Clinical Chemistry Analyzer is an automated chemistry analyzer that measures many different chemical analytes (Photo courtesy of Beckman Coulter)

Differential Biochemical Markers Identified in Inflammatory Processed Synovial Fluid

Joint infections with a non-specific presentation are difficult to diagnose, mainly due to the absence of specific clinical signs and symptoms, relative lack of accurate laboratory tests, low virulence due to previous treatment, and biofilm ability of the pathogens. More...
06 Oct 2021
Image: DxU Iris Workcell Urinalysis Solution (Photo courtesy of Beckman Coulter, Inc.)

New Urinalysis Solution Improves Laboratory Workflow by Reducing Manual Reviews and Sample Processing Time

Beckman Coulter, Inc. (Brea, CA, USA) has launched the DxU Iris Workcell, its new fully automated system that streamlines urinalysis workflow and reduces manual reviews to 4%. More...
05 Oct 2021
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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