Clinical Chemistry

CSF Test Developed for Uncommon Brain Diseases
Scientific studies have linked the abnormal deposition of tau in the brain to at least 25 different neurodegenerative diseases. However, to accurately diagnose these diseases, brain tissue often must be analyzed after the patient has died. More...30 Oct 2019


Fluorimetric Assay Quantifies Galactocerebrosidase Activity in Dried Blood Spots
The lysosomal enzyme galactocerebrosidase hydrolyzes glycosidic bonds of several glycosphingolipids, including galactose from galactosylsphingosine (psychosine), and is essential to prevent the toxic accumulation of psychosine in the body. More...29 Oct 2019


Metabolic Classification of Thyroid Nodules Uses MS Imaging
Fine-needle aspiration (FNA) biopsy is a well-established technique for diagnosis of suspicious thyroid lesions. However, histologic discrimination between malignant and benign thyroid nodules from FNA can be challenging. More...26 Oct 2019

Pre-Analytical Protocols Compared for Serotonin Quantification
Serotonin (5-hydroxytryptamine) is an important neurotransmitter and neuromodulator, which affects many neurophysiological processes, mood and cognition, regulates motility and sensibility in the bowel, and has an essential role in regulating blood pressure. More...24 Oct 2019

Presepsin Concentrations Correlate with Kidney Function Decline
Sepsis is an important public health problem with more than 750,000 patients reported yearly in the USA with similar figures in Europe. Sepsis continues to be a challenge for practitioners, as sepsis mortality rates are still high despite new antimicrobial and resuscitation agents. More...24 Oct 2019
In Other News
Automated Urine Analyzer And Components Evaluated
Liver Biomarkers Tied to Glycemic Control in Diabetes
Human CRP-Levels Compared Using Point-of-Care Methods
Insulin Sensitivity and Adiponectin Level Predict Insulin Therapy Response
Deficiency of Vitamin D Linked to Increased Mortality
C‐Peptide Associated with NAFLD Inflammatory Progression
Methionine Levels Tied to Diabetes in Children
Biomarkers Panel Used for Pleural and Peritoneal Effusions Diagnosis
Bone and Cartilage Biomarkers Analyzed for Knee Osteoarthritis
New Method May Lower Costs Associated with HDL-CEC Measurements
Protein Panel Developed for Early Detection of Lung Cancer
Biomarker Identified for Early Beta-Cell Death in Type 1 Diabetes
Serum HMGB1 Levels Reflect Clinical Features of HLH
Increased Risk of Hypoandrogenemia Found in Obese Young Men
New Blood Test Helps Detect Brain Injury in Minutes
Gout Increases Risk of Advanced Chronic Kidney Disease
Blood Sugar Levels Affect Risks in Type 1 Diabetes
Specific Phenotype Narrows Risk of Preeclampsia
Analytical Performance Evaluated for Troponin T Gen 5 Assay
Persistent C-Peptide Secretion in Type 1 Diabetes Genetic-Related
Proteinuria Contributes to Greater CKD Progression Risk in Men
Platelet Volume Related to Geriatric Patient In-Hospital Mortality
C-Reactive Protein Point-Of-Care Test Evaluated
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.