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Clinical Chemistry

Image: N-terminal pro-B-type natriuretic peptides (NT-proBNP) concentration could mean drastically different absolute risks of heart failure (HF) for different demographics (Photo courtesy of TCTMD)

NT-proBNP Underestimates Heart Failure Risk for Certain Patients

The N-terminal pro-B-type natriuretic peptides (NT-proBNP) concentration could mean drastically different absolute risks of heart failure (HF) for different demographics, according to a cohort study suggesting the importance of sex and race in interpreting risk for people free of HF at baseline. More...
03 May 2022
Image: Study demonstrates significant inconsistencies with pediatric reference interval (Photo courtesy of Unsplash)

Groundbreaking Study Points to Crucial Gap in Children’s Clinical Testing

A groundbreaking study has demonstrated significant inconsistencies with pediatric reference intervals, which are essential to high quality pediatric medical testing. More...
03 May 2022
Image: Nanotechnology-enabled low-cost, POC test detects sodium (Photo courtesy of Pexels)

Paper-Based Sensor Strip Rapidly Detects Sodium in Urine and Blood at POC

A team of researchers has developed nanotechnology-based paper sensor strips to detect sodium focus in urine and blood serum that could revolutionize scientific analysis. More...
29 Apr 2022
Image: The Randox Lipoprotein(a), (Lp(a)), assay offers a truly accurate method for the assessment of Lp(a) in serum or plasma (Photo courtesy of Randox Laboratories)

Elevated Lipoprotein(a) Mediates Risk of Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults, with a prevalence between 0.5% and 2%. Longer life span and higher prevalence of AF risk factors are projected to further increase the global prevalence of AF. More...
27 Apr 2022
Image: Randox Daytona RX chemical analyzer (Photo courtesy of Gemini BV)

Urine Testing Differentiates Glomerular from Tubulointerstitial Diseases on Kidney Biopsy

Histological examination of kidney biopsy tissue can help differentiate between glomerular and tubulointerstitial diseases, as well as differentiate between their underlying etiologies and subtypes. More...
22 Apr 2022
Image: The Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometer (Photo courtesy of Creative Proteomics)

Lipidomics Approach Developed to Predict Cardiovascular Disease, Diabetes

Current detection of cardiovascular disease and diabetes relies heavily on factors such as patient history, sex, age, body mass index, as well as blood panels measuring blood glucose and lipid metabolites, such as high- and low-density cholesterol and triglycerides. More...
18 Apr 2022
Image: The ARCHITECT i2000SR immunoassay analyzer (Photo courtesy of Abbott)

Sex Hormones Influence HbA1c Levels in Non-Diabetic Population

Sex hormones, including estrogen, progesterone, and androgens, are synthesized by the human gonads and adrenal cortex. Their main role is to promote development of the reproductive system and maintain secondary sexual characteristics. More...
15 Apr 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.