BioResearch

Nanoparticle Assay Detects Respiratory Bacteria in Pneumonia Model
Researchers used a mouse pneumonia model to demonstrate how a nanoparticle-based technique could be used to detect Pseudomonas aeruginosa bacteria in infected animals and monitor bacterial clearance from their lungs during the course of antibiotic treatment. More...13 Dec 2018

Deeply Penetrating Nanoparticles Designed to Treat Osteoarthritis
A novel nanoparticle-based drug transport system designed to treat osteoarthritis delivers the anabolic growth factor IGF-1 (insulin-like growth factor 1) directly to injured chondrocytes, which are located deep within a dense layer of cartilage tissue. More...12 Dec 2018

Diabetes Researchers Convert Stem Cells into Insulin-Producing Cells
A team of stem cell biologists working on the problem of pancreas replacement in patients with type I diabetes identified the extrinsic and intrinsic signaling mechanisms that coordinate the fate-determining transcriptional events underlying the maturation of bipotent pancreatic progenitors and used this information to convert these pancreatic progenitors - derived from human embryonic stem cells - to insulin-producing islet cells. More...11 Dec 2018


Mannose Treatment Enhances Chemotherapy and Slows Growth of Cancers
Cancer researchers have found that treatment with mannose leads to growth retardation in several tumor types in vitro and in a mouse model system and enhances cell death in response to major forms of chemotherapy. More...05 Dec 2018

In Other News
Subpopulation of Fibroblasts Drives Breast Tumor Development
African Folk Drug Modulates Critical Potassium Channel Protein
Protein Crystals Used to Prepare Cellular Drug Delivery Nanotubes
Modified Nanoparticle Drug Carriers Target Solid Tumors in Model
New Method Eliminates Unwanted Neurons from Cultures of Kidney Organoids
Linked Antibodies Provide Universal Protection from Influenza Infection
Technology Evaluated for T-cell Receptor Identification and Cloning
Nanoneedle Bio-patch Provides Minimally Invasive Drug Delivery
Mutation in p53 Suppressor Gene Drives Tumor Development
Biodegradable Nanoscaffolds Improve Chances for Stem Cell Therapies
In vivo CRISPR/Cas9 Therapy Prevents Arrhythmias in Model
Mechanism Explains Why Damaged DNA Accumulates in ALS Neurons
Immune Sensitivity Hampers Clinical Applications of CRISPR/Cas9
Proposed Treatment Aims to Re-Sensitize Cancer Cells
Tumor-Secreted Ligands Induce Fibroblast Behavior
Novel CDK9 Inhibitor Prevents Cancer Growth
Dysregulation of Retinoic Acid Signaling in Stem Cells Spurs Tumor Growth
Functional 3D Neural Network Models Generated from Stem Cells
Antisense DNA Drug Cures Prostate Cancer in Model
Researchers Aim to Reduce Variability of Gene Therapy Vectors
Candidate Anticancer Drug Effectively Treats Drug-resistant Pancreatic Cancer
Gene Mutation Reduces Glucose Uptake and Premature Mortality
Long Non-Coding RNA Identified Modulates Synaptic Morphology and Function
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.







