BioResearch
Inhibition of a Tyrosine Kinase in Mouse Models Decreased Tumor Growth and Metastasis
Studies with genetically engineered mouse models of breast cancer, melanoma, and colon cancer have shown that inhibiting the action of the tyrosine kinase MerTK increased the ability of the animals to produce an active immune response and blocked tumor growth and metastasis. More...24 Jul 2013
BRAF Mutation Triggers Series of Cellular Transformations Leading to Colon Cancer
Cancer researchers have found that the activity of the protein encoded by the mutant BRAFV600E gene triggers a series of transformations that convert normal cells in the colon into a precancerous and ultimately fully cancerous state. More...23 Jul 2013
New Chemotherapeutic Approach Will Selectively Starve Cancer Cells
Blocking the activity of the enzyme eukaryotic elongation factor 2 kinase, which is found in cancer cells but not in normal cells, prevents tumors from adapting to nutrient deprivation and may represent a new chemotherapeutic approach. More...21 Jul 2013
Genetically Engineered Mouse Models That Closely Resemble Human Patients Enable More Relevant Cancer Drug Studies
The use of genetically engineered mouse models as recipients for xenografts of various types of human tumors enables study of tumor growth that can be used to predict the responsiveness of these tumors to drug treatment. More...18 Jul 2013
Blocking Action of a Macrophage Surface Protein Limits Damage in Chronic Inflammatory Diseases
The macrophage integral membrane protein CD36 has been identified as a central regulator of inflammasome activation in several chronic inflammatory disease such as atherosclerosis, Alzheimer's disease, and diabetes. More...18 Jul 2013
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In Other News
NMR Innovation Offers Insights into Protein Interaction
A Novel Cellular Thermal Shift Assay Monitors Intracellular Drug Binding
Disrupted Micronuclei Cited as Potential Non-Small-Cell Lung Cancer Biomarkers
Hydrogels Assessed for Biomedical Uses
Computational Modeling Yields Potential Anti-Adenovirus Drugs
Analysis Reveals Detailed Structural Features of Amyloid Oligomers
Human Clinical Trial Shows Stem Cell Therapy Hastens Bone Repair
Sialyltransferase Initiates New Line of Sugar-Modifying Enzymes
Tracing Technique Untangles Brain Circuit Networks
Signaling Regulatory Protein Found That Mediates Metastasis of Human Colorectal Cancer Cells
Sugar Solution Turns Tissues See-Through
New Imaging Technology Accelerates Multiple Sclerosis Research
Usurping Host DNA Repair Mechanisms Enables Hepatitis B Virus to Evade Replication Inhibitors
Prototype Microarray System Automates Antimicrobial Drug Development
Growth Factors Identified for Current Orphan Drug Market
New Anticancer Therapy to Target Cancer Cells' Elevated Need for Heme
Online Software Designed to Enhance Target Enrichment Custom Design Process for Next-Generation Sequencing
Chemical Nanoengineering Advance in Designing Light-Controlled Drugs
Osteoporosis Drug Stops Growth of Breast Cancer Cells, Even in Resistant Tumors
Ultrahigh Resolution of 3D Human Brain Offered Free for Researchers
Experimental Drug Restores Communication Between Synapses in Mouse Alzheimer's Disease Model
Investigational Thiophene Drug Kills Tuberculosis Bacteria by Blocking Mycolic Acid Synthesis
Novel Monoclonal Antibody Blocks Breast Cancer Metastasis in Mouse Model
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
