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BioResearch

Signaling Regulatory Protein Found That Mediates Metastasis of Human Colorectal Cancer Cells

The direct effect of the signaling regulatory protein km23-1 on TGF-beta defines its role in mediating the migration, invasion, and tumor growth of human colorectal carcinoma cells. More...
09 Jul 2013
Image: Various mouse tissues before and after immersion in SeeDB (Photo courtesy of RIKEN).

Sugar Solution Turns Tissues See-Through

A new study describes a sugar and water-based solution that turns tissues transparent in just three days, without disrupting the shape and chemical nature of the samples. More...
09 Jul 2013
Image: A frequency-based MRI image of an MS patient shows changes in tissue structure (Photo courtesy of the University of British Columbia).

New Imaging Technology Accelerates Multiple Sclerosis Research

Canadian investigators have developed a new MRI technique that detects the characteristic signs of multiple sclerosis in finer detail than ever before, providing a more effective tool for evaluating new treatments. More...
09 Jul 2013
Image: The interaction of HBV circular DNA with host UNG (uracil-DNA glycosylase), (Photo courtesy of Kanazawa University).

Usurping Host DNA Repair Mechanisms Enables Hepatitis B Virus to Evade Replication Inhibitors

Virologists used a duck hepatitis B virus (DHBV) model to examine the molecular pathways involved in maintaining the integrity of the virus' circular DNA, which modulates the transition from an acute infection into a chronic disease. More...
08 Jul 2013

Prototype Microarray System Automates Antimicrobial Drug Development

A prototype microarray system enables automatic screening of 1,200 individual bacterial or fungal cultures for their response to candidate drugs or other compounds. More...
08 Jul 2013

Growth Factors Identified for Current Orphan Drug Market

A new market research report by Kalorama Information identifies factors likely to have stimulated the current orphan drug market, with further growth expected for the next forecast period. More...
08 Jul 2013
Image: Space-filling model of heme (Photo courtesy of Wikimedia Commons).

New Anticancer Therapy to Target Cancer Cells' Elevated Need for Heme

Cancer cells have metabolic requirements that separate them from normal cells, and render them vulnerable to drugs that target these processes. More...
04 Jul 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.