BioResearch
Nanocarriers Deploy Enzymes for Targeted Delivery of Anticancer Drugs
A newly devised nanocarrier delivery system transports a combination of anticancer and anti-angiogenesis drugs to the site of a tumor where the acidic environment releases them to damage the cancer cells and deprive them of nutrients by blocking creation of new blood vessels. More...08 Feb 2016
Gene Editing Technique Corrects Patient-Derived Stem Cell Mutation
The relatively new CRISPR/Cas9 gene editing technique was used to correct a mutation in the genome of stem cells derived from skin cells taken from patients with the hereditary optical disorder retinitis pigmentosa. More...08 Feb 2016
Antibiotic Resistant Bacteria Succumb to Treatment with Unique Natural Clay
A team of Canadian medical microbiologists has demonstrated the potential use of a unique type of natural clay for treating pathogenic bacteria that have become resistant to the commonly used antibiotics. More...07 Feb 2016
![Image: Molecular model of E3 ubiquitin ligase (green), E2 ubiquitin enzyme (orange), \"activated ubiquitin\" (cyan), and \"allosteric ubiquitin\" (blue) (Photo courtesy of Dr. Bernhard Lechtenberg, Sanford Burnham Prebys Medical Discovery Institute).](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2016-02-03/GMS-035.jpg "Image: Molecular model of E3 ubiquitin ligase (green), E2 ubiquitin enzyme (orange), \\"activated ubiquitin\\" (cyan), and \\"allosteric ubiquitin\\" (blue) (Photo courtesy of Dr. Bernhard Lechtenberg, Sanford Burnham Prebys Medical Discovery Institute).")
Researchers Resolve Molecular Structure of Critical Ubiquitin-Binding Enzyme
The molecular structure of a protein complex critically involved in diverse cellular functions such as cell signaling, DNA repair, and mounting anti-inflammatory and immune responses has been elucidated and presented in a recent paper. More...03 Feb 2016
Biochemists Present First 3D Crystal Structure of a Nonribosomal Peptide Synthetase
A team of Canadian biochemists has presented a series of three-dimensional X-ray crystallography structures of the initiation module of the antibiotic-producing nonribosomal peptide synthetase megaenzyme, linear gramicidin synthetase. More...
03 Feb 2016
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Photoactivated Nanoparticles Block Pancreatic Cancer Growth and Metastasis in Mouse Models
Antibodies Isolated from Ebola Survivors Recognize Wide Range of Ebolavirus Species
Researchers Co-opt Slow DNA Release to Improve Accuracy of CRISPR/Cas9 Genome Editing
ApoE4 Linked to Various Diseases by Transcription Factor Activity
Purchase Agreement to Boost Ebola Vaccine Development
Synthetic RNA Improves the CRISPR/Cas 9 Genome Editing Tool
First High-Throughput Imaging Platform for Predicting Kidney Toxicity of Chemicals
Protein Identified That Boosts Brain Tumor Resistance to Chemotherapy
Induced Pluripotent Stem Cells Flourish in Novel 3D Culture System
Genetically Engineered Mouse Model Mimics Rare Human Bone Disorder
Exosome Delivery Dramatically Boosts Anticancer Drug Potency
Pulmonary Neuroendocrine Cells Function as Airway Sensors to Control Immune Response in the Lung
Macrophages Lacking Ubiquitin-Binding Protein Stimulate Growth of Atherosclerotic Plaques
Biotech Companies Agree to Commercialize an Anticancer PARP Inhibitor Drug
Key Finding May Lead to Improved Treatment of Aggressive Brain Cancers
Novel Combination of Nanotechnology and Gene Therapy Repairs Damaged Arterial Walls
Bacterial Toxins Promote Growth of Rare Skin Cancer
Blocking ERK Signaling Inhibits Growth of Some Pancreatic Cancer Cell Lines
Bioengineered Connective Tissue to Promote Development of Treatment Strategies
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.