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BioResearch

Image: Biomedical engineering researchers have developed a technique for creating microscopic “depots” for trapping drugs inside cancer tumors. In an animal model, these drug depots were more effective at shrinking tumors than the use of the same drugs without the depots (Photo courtesy of Quanyin Hu, University of North Carolina).

Nanocarriers Deploy Enzymes for Targeted Delivery of Anticancer Drugs

A newly devised nanocarrier delivery system transports a combination of anticancer and anti-angiogenesis drugs to the site of a tumor where the acidic environment releases them to damage the cancer cells and deprive them of nutrients by blocking creation of new blood vessels.   More...
08 Feb 2016
Image: Skin cells from a patient with X-linked retinitis pigmentosa were transformed into induced pluripotent stem cells and the blindness-causing point mutation in the RPGR gene was corrected using CRISPR/Cas9 (Photo courtesy of Dr. Vinit Mahajan, University of Iowa).

Gene Editing Technique Corrects Patient-Derived Stem Cell Mutation

The relatively new CRISPR/Cas9 gene editing technique was used to correct a mutation in the genome of stem cells derived from skin cells taken from patients with the hereditary optical disorder retinitis pigmentosa.  More...
08 Feb 2016
Image: Naturally occurring clay from Kisameet Bay, Canada, exhibits potent antibacterial activity against multidrug-resistant pathogens (Photo courtesy of Kisameet Glacial Clay Inc.).

Antibiotic Resistant Bacteria Succumb to Treatment with Unique Natural Clay

A team of Canadian medical microbiologists has demonstrated the potential use of a unique type of natural clay for treating pathogenic bacteria that have become resistant to the commonly used antibiotics.  More...
07 Feb 2016
Image: The Zeiss Axiocam 512 color microscope camera (Photo courtesy of Carl Zeiss Meditec).

Zeiss Introduces New Digital Microscope Cameras

Carl Zeiss Meditec has released two new digital microscope cameras that complement their current portfolio of high-speed USB 3.0 microscope cameras.  More...
07 Feb 2016
Image: The Cognionics wearable 72-channel EEG headset (Photo courtesy of Cognionics).

Portable Monitoring System Tracks Real-Time Brain Activity

An innovative wearable brain activity monitoring system with dry electroencephalogram sensors provides a better solution for real-world applications.  More...
07 Feb 2016
Image: Molecular model of E3 ubiquitin ligase (green), E2 ubiquitin enzyme (orange), \"activated ubiquitin\" (cyan), and \"allosteric ubiquitin\" (blue) (Photo courtesy of Dr. Bernhard Lechtenberg, Sanford Burnham Prebys Medical Discovery Institute).

Researchers Resolve Molecular Structure of Critical Ubiquitin-Binding Enzyme

The molecular structure of a protein complex critically involved in diverse cellular functions such as cell signaling, DNA repair, and mounting anti-inflammatory and immune responses has been elucidated and presented in a recent paper.  More...
03 Feb 2016

Biochemists Present First 3D Crystal Structure of a Nonribosomal Peptide Synthetase

A team of Canadian biochemists has presented a series of three-dimensional X-ray crystallography structures of the initiation module of the antibiotic-producing nonribosomal peptide synthetase megaenzyme, linear gramicidin synthetase.  More...
03 Feb 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.