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BioResearch

Image: A micrograph of eosinophilic esophagitis (EoE), H&E stain. Characteristic features are present: Abundant eosinophils—criteria vary; one common definition is: > 20 eosinophils/0.24 mm2; Papillae are elongated; papillae reach into the top 1/3 of the epithelial layer; Basal cell hyperplasia; > 3 cells thick or >15% of epithelial thickness; Spongiosis (Photo courtesy of Wikimedia).

Pathway Implicated in Development of Eosinophilic Esophagitis

Scientists have identified a protein whose dysfunction appears to be involved in causing the tissue damage in patients with eosinophilic esophagitis (EoE). The finding may lead to improved pathology analysis, diagnostics, and specific drug therapies for patients. More...
26 Apr 2016
Image: A transmission electron micrograph (TEM) image of the Zikavirus (red disks) (Photo courtesy of the CDC).

Mouse Model Study Supports Sexual Transmission of Zikavirus Infection

A newly established mouse model, which is expected to accelerate efforts to develop a vaccine to protect against Zikavirus (ZIKV) infection, revealed high levels of the virus in the testes of the animals, a finding that supports the possible sexual transmission of the disease. More...
26 Apr 2016
Image: The lipid raft organization, region (1) is standard lipid bilayer, while region (2) is a lipid raft (Photo courtesy of Wikimedia Commons).

Ganglioside Probes Enable Tracking of Membrane Lipid Rafts in Living Cells

A team of Japanese cell biologists developed a series of fluorescently labeled gangliosides that enabled them to visualize cell membrane lipid raft domains in living cells. More...
26 Apr 2016
Image: An example of magnetite with sharp, lustrous, jet-black crystals (Photo courtesy of Wikimedia Commons).

Enzyme-Loaded Magnetic Nanoparticles Suitable for Therapeutic and Industrial Applications

Members of a novel class of nano-sized transport vessels are composed of only two biocompatible components: an enzyme and magnetite nanoparticles. More...
25 Apr 2016
Image: A scanning electron microscope (SEM) image of animal cells (colored blue) cultured on an array of carbon nanotubes (Photo courtesy of the University of Rochester).

Carbon Nanotube-Based Device Efficiently Transports Nucleic Acids into Cell Cultures

A novel device based on carbon nanotubes arranged in "honeycomb-like" structures was used to safely and efficiently transfer genetic material into cultures of different types of human and animal cells. More...
25 Apr 2016
Image: A photomicrograph showing that breast tumor cells have high levels of LIPG (endothelial lipase) expression in their membranes (Photo courtesy of the Institute for Research in Biomedicine, Barcelona).

Supply of Lipid Precursors Modulates Growth of Breast Cancer Cells

An enzyme present in the cell membranes of breast cancer cells, which supplies lipid precursors that enable rapid cell growth, has emerged as a promising drug target.  More...
21 Apr 2016

DNA Synthesis Specialists Acquire Advanced Software Design Capabilities

An American biotech firm that develops and produces synthetic DNA has established an international presence by purchasing an Israeli genetic design software company.  More...
21 Apr 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.