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BioResearch

Innovative DNA Technology May Provide More Efficient Disease Detection and Treatment

Researchers have developed a novel DNA aptamer with potential to improve detection and targeted treatment of infectious diseases and other illnesses, such as cancer.  More...
17 Feb 2016
Image: Space-filling model of part of the crystal structure of calcium carbonate, CaCO3 (Photo courtesy of Wikimedia Commons).

Calcium Carbonate Nanoparticles Stop Cancer by Neutralizing the Tumor Microenvironment

Tumor growth was halted in a mouse cancer model by the injection of novel calcium carbonate nanoparticles that neutralized the pH of the tumor microenvironment.  More...
17 Feb 2016
Image: Topographic AFM (left) and DREEM phase (right) images of large TRF2 complexes (Photo courtesy of NCSU).

New Imaging Technique Provides Insights on Telomere Structure

A new microscopy technique enables direct visualization of DNA wrapping outside and around histone proteins, such as in telomeres.  More...
16 Feb 2016
Image: The majority of kidney cell carcinomas are missing the VHL tumor-suppressor gene. These renal cancer cells remain healthy when all nutrients are present (left panel), but quickly swell up and die of necrosis when deprived of cystine (right panel) (Photo courtesy of Chien-Kuang Ding, Duke University).

Lack of Cystine Kills Renal Cancer Cells in Mouse Model

Restricting access to a specific extracellular nutrient—the amino acid cysteine—caused the death of certain types of renal cancer cells both in culture and in a kidney cancer mouse model.  More...
16 Feb 2016
Image: Source, input images, shuffled, and reordered images using the optical brush (Photo courtesy of MIT Media lab).

Optical Fiber Brush Provides Flexible Imaging Interface

Computational techniques and ultrafast imaging have been combined to create a flexible fiber interface for imaging, with no need for lenses or a protective housing.  More...
16 Feb 2016
Image: Hepatitis E virus capsids can resist passing through the digestive system. These virus-like particles can be modified to target specific cell types and could be used to carry vaccines or drugs into the body through the oral route. (Photo courtesy of Marie Stark, University of California, Davis).

Viral Protein Coat-Based Nanoparticle Delivery System Targets Breast Cancer Cells

A novel transport system for targeted delivery of toxic chemotherapeutic agents or labile protein-based vaccines was based on nanoparticles fashioned from empty hepatitis E virus capsids.  More...
15 Feb 2016

Partners Seek to Develop Rare Monoclonal Antibodies for Therapeutic Use

A recently publicized collaborative research agreement is set to boost the use of a high-throughput single cell antibody platform for the discovery of rare monoclonal antibodies for therapeutic use.  More...
15 Feb 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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