Next-Gen Electrolyte Analyzers with Bio-Sensor Cartridge Technology Simplify Clinical Analysis
By LabMedica International staff writers Posted on 10 Jul 2023 |

Electrolytes and metabolites offer valuable insights into the body's metabolic processes. Electrolyte analyzers measure ion concentrations in the blood, such as potassium, sodium, bicarbonate, chloride, calcium, glucose, lactate, and magnesium. This analysis helps identify medical conditions like kidney failure, heart failure, uncontrolled diabetes, hemorrhage, chemical poisoning, drug overdose, shock, asthma, and chronic obstructive pulmonary disease (COPD). One of the significant long-term advancements in the electrolyte analyzer market is the creation of technologically enhanced devices and the utilization of sophisticated sensors for monitoring critical parameters like pH level and electrolyte concentration. Now, next-generation electrolyte analyzers with advanced features enable increased accuracy and productivity while shortening the turnaround time for each sample, and reducing human input errors.
The CBS series, a direct ISE analyzer, from B&E Biotechnology Co. Ltd. (Yantai, China) measures whole blood or serum samples directly without the need for dilution. The CBS series (e.g., the CBS-5) measures pH, K, Na, Cl, iCa, and TCO2, and offer simple module replacement. These analyzers come with a 20-hole sample tray and can test 60 samples per hour. The CBS series is popular in numerous countries worldwide, with approximately 10,000 units currently installed. Additionally, the company also offers the KS series of indirect ISE analyzers (e.g., the KS 401) which can automatically dilute samples up to 20 times for testing and can process up to 120 samples per hour. They offer easy electrode module replacement and have a long module lifespan (10,000 samples or two months of operation). With capabilities such as switching between serum mode and urine mode with a single click, direct total calcium testing, and a 60-hole sample tray, the KS series is particularly suitable for medium-sized hospitals. Due to its small sample size, flexibility, and ease of use, the KS series is also making waves in the global market.
Both the CBS and KS series of analyzers utilize multi-sensor modules developed from B&E's extensive technical experience in multi-biosensor technology (MBT). The modules, comprising ceramic plates and specific ion-selective membrane ingredients, exhibit impressive linearity, reproducibility, and long-term stability. Leveraging its MBT applications, B&E has also developed an electrolyte biosensor unit (EBU) that can be adapted to automatic biochemistry analyzers for electrolyte analysis to dramatically reduce running costs.
Related Links:
B&E Biotechnology Co. Ltd.
Latest Clinical Chem. News
- VOCs Show Promise for Early Multi-Cancer Detection
- Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC
- Gold Nanoparticles to Improve Accuracy of Ovarian Cancer Diagnosis
- Simultaneous Cell Isolation Technology Improves Cancer Diagnostic Accuracy
- Simple Non-Invasive Hair-Based Test Could Speed ALS Diagnosis
- Paper Strip Saliva Test Detects Elevated Uric Acid Levels Without Blood Draws
- Prostate Cancer Markers Based on Chemical Make-Up of Calcifications to Speed Up Detection
- Breath Test Could Help Detect Blood Cancers
- ML-Powered Gas Sensors to Detect Pathogens and AMR at POC
- Saliva-Based Cancer Detection Technology Eliminates Need for Complex Sample Preparation
- Skin Swabs Could Detect Parkinson’s Years Before Symptoms Appear
- New Clinical Chemistry Analyzer Designed to Meet Growing Demands of Modern Labs
- New Reference Measurement Procedure Standardizes Nucleic Acid Amplification Test Results
- Pen-Like Tool Quickly and Non-Invasively Detects Opioids from Skin
- Simple Urine Test Could Detect Multiple Cancers at Early Stage
- Earwax Test Accurately Detects Parkinson’s by Identifying Odor Molecules
Channels
Molecular Diagnostics
view channel
Liquid Biopsy Test Enables Early Detection of ICI-Related Myocarditis
Cancer treatments have advanced significantly in recent years, but they can still trigger severe and sometimes fatal side effects. Immune checkpoint inhibitors (ICIs), which have transformed cancer therapy,... Read more
Rapid POC Diagnostic Test Detects Asymptomatic Malaria Cases
Malaria is one of the leading causes of preventable deaths worldwide, with around 95% of all deaths occurring in Africa. Asymptomatic infections are a major driver of ongoing transmission because individuals... Read moreHematology
view channel
Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage
Postpartum hemorrhage, severe bleeding after childbirth, remains one of the leading causes of maternal mortality worldwide, yet many of these deaths are preventable. Standard care can be hindered by delays... Read more
Pioneering Model Measures Radiation Exposure in Blood for Precise Cancer Treatments
Scientists have long focused on protecting organs near tumors during radiotherapy, but blood — a vital, circulating tissue — has largely been excluded from dose calculations. Each blood cell passing through... Read more
Platelets Could Improve Early and Minimally Invasive Detection of Cancer
Platelets are widely recognized for their role in blood clotting and scab formation, but they also play a crucial role in immune defense by detecting pathogens and recruiting immune cells.... Read more
Portable and Disposable Device Obtains Platelet-Rich Plasma Without Complex Equipment
Platelet-rich plasma (PRP) plays a crucial role in regenerative medicine due to its ability to accelerate healing and repair tissue. However, obtaining PRP traditionally requires expensive centrifugation... Read moreImmunology
view channel
Blood Test Tracks Treatment Resistance in High-Grade Serous Ovarian Cancer
High-grade serous ovarian cancer (HGSOC) is often diagnosed at an advanced stage because it spreads microscopically throughout the abdomen, and although initial surgery and chemotherapy can work, most... Read more
Luminescent Probe Measures Immune Cell Activity in Real Time
The human immune system plays a vital role in defending against disease, but its activity must be precisely monitored to ensure effective treatment in cancer therapy, autoimmune disorders, and organ transplants.... Read more
Blood-Based Immune Cell Signatures Could Guide Treatment Decisions for Critically Ill Patients
When a patient enters the emergency department in critical condition, clinicians must rapidly decide whether the patient has an infection, whether it is bacterial or viral, and whether immediate treatment... Read moreMicrobiology
view channel
Fast Noninvasive Bedside Test Uses Sugar Fingerprint to Detect Fungal Infections
Candida bloodstream infections are a growing global health threat, causing an estimated 6 million cases and 3.8 million deaths annually. Hospitals are particularly vulnerable, as weakened patients after... Read more
Rapid Sepsis Diagnostic Device to Enable Personalized Critical Care for ICU Patients
Sepsis is a life-threatening condition that occurs when the body’s response to infection spirals out of control, damaging organs and leading to critical illness. Patients often arrive at intensive care... Read morePathology
view channel
AI Improves Cervical Cancer Screening in Low-Resource Settings
Access to cervical cancer screening in low- and middle-income countries remains limited, leaving many women without early detection for this life-threatening disease. The lack of access to laboratories,... Read more
New Multi-Omics Tool Illuminates Cancer Progression
Tracking how cancers evolve into more aggressive and therapy-resistant forms has long been a challenge for researchers. Many current tools can only capture limited genetic information from tumor samples,... Read moreTechnology
view channel
Acoustofluidic Device to Transform Point-Of-Care sEV-Based Diagnostics
Rapid and sensitive detection of small extracellular vesicles (sEVs)—key biomarkers in cancer and organ health monitoring—remains challenging due to the need for multiple preprocessing steps and bulky... Read more
AI Algorithm Assesses Progressive Decline in Kidney Function
Chronic kidney disease (CKD) affects more than 700 million people worldwide and remains a major global health challenge. The condition often progresses silently, and many patients remain undiagnosed until... Read more
Taste-Based Influenza Test Could Replace Nasal Swabs with Chewing Gum
Influenza is one of the most dangerous infectious diseases worldwide, claiming around half a million lives each year. What makes it particularly insidious is that flu viruses are contagious even before... Read more
3D Micro-Printed Sensors to Advance On-Chip Biosensing for Early Disease Detection
Early-stage disease diagnosis depends on the ability to detect biomarkers with exceptional sensitivity and precision. However, traditional biosensing technologies struggle with achieving this at the micro-scale,... Read moreIndustry
view channel
Hologic to be Acquired by Blackstone and TPG
Hologic (Marlborough, MA, USA) has entered into a definitive agreement to be acquired by funds managed by Blackstone (New York, NY, USA) and TPG (San Francisco, CA, USA) in a transaction valued at up to... Read more
Bio-Techne and Oxford Nanopore to Accelerate Development of Genetics Portfolio
Bio-Techne Corporation (Minneapolis, MN, USA) has expanded its agreement with Oxford Nanopore Technologies (Oxford, UK) to broaden Bio-Techne's ability to develop a portfolio of genetic products on Oxford... Read more
Terumo BCT and Hemex Health Collaborate to Improve Access to Testing for Hemoglobin Disorders
Millions of people worldwide living with sickle cell disease and other hemoglobin disorders experience delayed diagnosis and limited access to effective care, particularly in regions where testing is scarce.... Read more