通过一次检验检测所有现有的H5N1毒株
|
By LabMedica International staff writers Posted on 05 Sep 2012 |
新加坡一家研究所和一家医院的科学家们成功开发了一款禽流感诊断试剂盒。
这种先进的试剂盒使医生能够通过一次检验快速检测所有的现有H5N1病毒,准确率几乎达到100%。这将促进公共医疗系统,并将帮助全世界做好准备应对这一高度传染性且经常是致命性的疾病。
新型H5N1检验试剂盒的更准确名称是H5N1实时逆转录聚合酶链反应(RT-PCR)测定。它是目前市场上唯一能准确而迅速地检测所有已知H5N1禽流感甲型流感病毒毒株的检测试剂盒。
瑞士日内瓦的世界卫生组织(WHO; www.who.int)推荐的检测H5N1的现行金标准只能检测10种不同的基因分组(分化枝1、2和3)里的3种。WHO推荐的检测方法不可能检测所有现有的H5N1毒株。
新加坡科学技术与研究署(ASTAR; www.etc.a-star.edu.sg)下属实验治疗中心(ETC)的高级研究科学家暨技术发展项目主任Masafumi Inoue博士和新加坡陈笃生医院(TTSH; www.ttsh.com.sg)的高级医疗化验顾问Timothy Barkham博士共同开发的这款新发布的H5N1检验试剂盒已经过东南亚几所医院的临床确证。
这款新型检验试剂盒兼容以前发布的“四重”流感诊断试剂盒。后者正在泰国的几家地区医院使用。使用这类多重测定能够通过一次检验同时检测和鉴别不同类型的流感感染,从而为实验室节省时间和花费。
Inoue博士说:“我们的专业知识和技巧能为对抗H5N1病毒的斗争做出贡献,我们对此感到兴奋。我们的技术极大简化和加速了检测与鉴定H5N1新变种的过程。当病毒变异得更加危险时,比如获得抗药性,这样的信息就尤为重要。”
Related Links:Agency for Science and Technology Research >> www.etc.a-star.edu.sg
Tan Tock Seng Hospital >> www.ttsh.com.sg
World Health Organization >> www.who.int
这种先进的试剂盒使医生能够通过一次检验快速检测所有的现有H5N1病毒,准确率几乎达到100%。这将促进公共医疗系统,并将帮助全世界做好准备应对这一高度传染性且经常是致命性的疾病。
新型H5N1检验试剂盒的更准确名称是H5N1实时逆转录聚合酶链反应(RT-PCR)测定。它是目前市场上唯一能准确而迅速地检测所有已知H5N1禽流感甲型流感病毒毒株的检测试剂盒。
瑞士日内瓦的世界卫生组织(WHO; www.who.int)推荐的检测H5N1的现行金标准只能检测10种不同的基因分组(分化枝1、2和3)里的3种。WHO推荐的检测方法不可能检测所有现有的H5N1毒株。
新加坡科学技术与研究署(ASTAR; www.etc.a-star.edu.sg)下属实验治疗中心(ETC)的高级研究科学家暨技术发展项目主任Masafumi Inoue博士和新加坡陈笃生医院(TTSH; www.ttsh.com.sg)的高级医疗化验顾问Timothy Barkham博士共同开发的这款新发布的H5N1检验试剂盒已经过东南亚几所医院的临床确证。
这款新型检验试剂盒兼容以前发布的“四重”流感诊断试剂盒。后者正在泰国的几家地区医院使用。使用这类多重测定能够通过一次检验同时检测和鉴别不同类型的流感感染,从而为实验室节省时间和花费。
Inoue博士说:“我们的专业知识和技巧能为对抗H5N1病毒的斗争做出贡献,我们对此感到兴奋。我们的技术极大简化和加速了检测与鉴定H5N1新变种的过程。当病毒变异得更加危险时,比如获得抗药性,这样的信息就尤为重要。”
Related Links:Agency for Science and Technology Research >> www.etc.a-star.edu.sg
Tan Tock Seng Hospital >> www.ttsh.com.sg
World Health Organization >> www.who.int
Latest 分子诊断 News
Channels
Clinical Chemistry
view channel
Blood Test Predicts Alzheimer Disease Risk Before Imaging Changes and Symptoms
Alzheimer's disease often advances silently for years, making timely risk stratification difficult in routine practice. Current approaches to detect pathology can involve lumbar puncture or positron emission... Read more
Study Finds ApoB Testing More Effective Than LDL for Guiding Lipid Therapy
Routine blood tests that measure low-density lipoprotein (LDL), commonly known as “bad” cholesterol, are widely used to guide lipid-lowering therapy, but they do not always provide a complete picture of... Read more
AI-Enabled POC Test Quantifies Multiple Cardiac Biomarkers
Cardiovascular diseases are a leading cause of death, responsible for nearly 20 million deaths each year. Timely triage of myocardial infarction and heart failure hinges on rapid cardiac biomarker measurement,... Read moreNext Generation Automated Analyzers Increase Throughput for Clinical Chemistry and Electrolyte Testing
Clinical laboratories continue to face staffing shortages, limited space, and growing test volumes that pressure chemistry and electrolyte workflows. Maintaining rapid turnaround times increasingly depends... Read moreMolecular Diagnostics
view channel
Ultrasensitive Assay Reveals Previously Undetected Tuberculosis in Hospital Patients
Tuberculosis remains the leading cause of death from an infectious disease worldwide, and diagnosis can be difficult when bacterial load is low or disease is atypical. In the United States, the disease... Read more
Study Confirms Barrett’s Esophagus as Precursor to Esophageal Cancer
Esophageal adenocarcinoma is rising in Western countries and is often detected late, limiting treatment options. Clinicians suspect many cases begin in Barrett’s esophagus, yet the precursor lesion is... Read moreHematology
view channel
Routine Blood Test Parameters Link Anemia to Cancer Risk and Mortality
Anemia detected in routine care can signal underlying pathology and is frequently encountered in adults. Because it is defined by hemoglobin levels below the normal range, it is often evaluated with red... Read more
Prognostic Tool Guides Personalized Treatment in Rare Blood Cancer
Chronic myelomonocytic leukemia (CMML) is a rare blood cancer in which acquired genetic mutations in bone marrow stem cells drive disease. Stem cell transplantation is the only curative option but carries... Read moreImmunology
view channel
Study Finds Influenza Often Undiagnosed in Winter Deaths
Seasonal influenza drives substantial excess mortality, yet its contribution is often obscured when infections go undiagnosed near the time of death. Many deaths occur outside hospitals or in older adults... Read moreCombined Screening Approach Identifies Early Leprosy Cases
Leprosy remains a significant public health concern, with more than 200,000 new cases reported globally each year and early disease often escaping routine laboratory detection. In its initial phase, bacterial... Read moreMicrobiology
view channel
Syndromic Panel Enables Rapid Identification of Bloodstream Infections
Bloodstream infections require rapid identification of causative pathogens and resistance determinants to guide therapy, yet laboratories often face pressure to deliver clinically relevant results quickly... Read more
RNA-Based Workflow Identifies Active Skin Microbes for Dermatology Research
Human skin carries diverse microbial communities that influence barrier function and inflammation, yet identifying which organisms are metabolically active has been challenging. DNA-based surveys catalog... Read more
Cost-Effective Sampling and Sequencing Workflow Identifies ICU Infection Hotspots
Intensive care units face persistent threats from hospital-acquired infections, increasingly driven by drug-resistant bacteria. Rapidly pinpointing environmental reservoirs and transmission hotspots remains... Read morePathology
view channel
Biomarker Predicts Immunotherapy Response and Prognosis in Colorectal Cancer
Colorectal cancer is common and often lethal, and therapeutic decision-making is complicated by heterogeneous tumor microenvironments. Immunotherapy benefits only a small subset of patients, around 5%,... Read more
Collaboration Applies AI Pathology to Predict Response to Antibody-Drug Conjugates
Antibody-drug conjugates (ADC) are reshaping oncology, yet scalable biomarkers that reliably predict which patients will benefit remain limited as treatment regimens and combinations grow more complex.... Read moreTechnology
view channel
AI Tool Predicts Non-Response to Targeted Therapy in Colorectal Cancer
Advanced bowel cancer remains difficult to treat, and many patients receive targeted therapies that do not help them but still cause harm. Clinicians need reliable ways to identify likely responders before... Read more
Integrated System Streamlines Pre-Analytical Workflow for Molecular Testing
Pre-analytical variation remains a leading source of inconsistent molecular test results and added costs, particularly when laboratories rely on multiple instruments and protocols. Standardizing nucleic... Read moreIndustry
view channel
Beckman Coulter Gains CE Mark for Rapid Assay Distinguishing Bacterial vs Viral Infections
Clinicians often struggle to distinguish bacterial from viral infections at first presentation because symptoms overlap and definitive culture or molecular results can take hours or days.... Read more







