High Blood Glucose Tied to Cardiovascular Risk in Diabetes
By LabMedica International staff writers Posted on 14 Aug 2020 |
By measuring glycated hemoglobin (HbA1c), clinicians are able to get an overall picture of what the average blood sugar levels have been over a period of weeks/months (Photo courtesy of Diabetes.co.uk).
Glycated hemoglobin (HbA1c) is a measure of an overall picture of what the average blood sugar levels have been over a period of weeks/months. If the blood sugar levels have been high over recent weeks, the hemoglobinA1c test will be higher.
Blood sugar is commonly considered too high if it is higher than 130 mg/dL before a meal or higher than 180 mg/dL two hours after the first bite of a meal. However, most of the signs and symptoms of high blood sugar do not appear until the blood sugar level is higher than 250 mg/dL.
Clinical Scientists at the Miguel Hernandez University (San Juan de Alicante, Spain) conducted a study with an aim to analyze the relationship between HbA1c levels, blood sugar and mayor adverse cardiovascular events (MACE) risk in diabetes patients over 70 years of age. In total 5,016 subjects were included with a mean age of 75.1 years (46.7% men). Primary endpoint was the incidence of MACE: all-cause mortality and/or hospital admission due to coronary heart disease or stroke.
The scientists reported that during an average follow-up of 49 months (4.1 years), 807 (16.1%) MACE were recorded. The incidence of MACE was 20.6 per 1,000-person-years. Variables significantly associated to the incidence of MACE were male gender (HR: 1.61), heart failure (HR: 2.26), antiplatelet therapy (HR: 1.39), oral antidiabetic treatment (HR: 0.74), antithrombotic treatment (HR: 1.79), while age, creatinine, HbA1c and peripheral arterial disease were time-depend associated variables.
The authors concluded that their results highlights the importance of HbA1c level in the incidence of cardiovascular events in older diabetic patients. The study was originally published online on June 27, 2020 in the journal Primary Care Diabetes.
Related Links:
Miguel Hernandez University
Blood sugar is commonly considered too high if it is higher than 130 mg/dL before a meal or higher than 180 mg/dL two hours after the first bite of a meal. However, most of the signs and symptoms of high blood sugar do not appear until the blood sugar level is higher than 250 mg/dL.
Clinical Scientists at the Miguel Hernandez University (San Juan de Alicante, Spain) conducted a study with an aim to analyze the relationship between HbA1c levels, blood sugar and mayor adverse cardiovascular events (MACE) risk in diabetes patients over 70 years of age. In total 5,016 subjects were included with a mean age of 75.1 years (46.7% men). Primary endpoint was the incidence of MACE: all-cause mortality and/or hospital admission due to coronary heart disease or stroke.
The scientists reported that during an average follow-up of 49 months (4.1 years), 807 (16.1%) MACE were recorded. The incidence of MACE was 20.6 per 1,000-person-years. Variables significantly associated to the incidence of MACE were male gender (HR: 1.61), heart failure (HR: 2.26), antiplatelet therapy (HR: 1.39), oral antidiabetic treatment (HR: 0.74), antithrombotic treatment (HR: 1.79), while age, creatinine, HbA1c and peripheral arterial disease were time-depend associated variables.
The authors concluded that their results highlights the importance of HbA1c level in the incidence of cardiovascular events in older diabetic patients. The study was originally published online on June 27, 2020 in the journal Primary Care Diabetes.
Related Links:
Miguel Hernandez University
Latest Clinical Chem. News
- 3D Printed Point-Of-Care Mass Spectrometer Outperforms State-Of-The-Art Models
- POC Biomedical Test Spins Water Droplet Using Sound Waves for Cancer Detection
- Highly Reliable Cell-Based Assay Enables Accurate Diagnosis of Endocrine Diseases
- New Blood Testing Method Detects Potent Opioids in Under Three Minutes
- Wireless Hepatitis B Test Kit Completes Screening and Data Collection in One Step
- Pain-Free, Low-Cost, Sensitive, Radiation-Free Device Detects Breast Cancer in Urine
- Spit Test Detects Breast Cancer in Five Seconds
- Electrochemical Sensors with Next-Generation Coating Advances Precision Diagnostics at POC
- First-Of-Its-Kind Handheld Device Accurately Detects Fentanyl in Urine within Seconds
- New Fluorescent Sensor Array Lights up Alzheimer’s-Related Proteins for Earlier Detection
- Automated Mass Spectrometry-Based Clinical Analyzer Could Transform Lab Testing
- Highly Sensitive pH Sensor to Aid Detection of Cancers and Vector-Borne Viruses
- Non-Invasive Sensor Monitors Changes in Saliva Compositions to Rapidly Diagnose Diabetes
- Breakthrough Immunoassays to Aid in Risk Assessment of Preeclampsia
- Urine Test for Monitoring Changes in Kidney Health Markers Can Predict New-Onset Heart Failure
- AACC Releases Comprehensive Diabetes Testing Guidelines