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Pathology

Image: Investigators evaluate results of the AQP1 ELISA, part of a noninvasive method to screen for kidney cancer by measuring the presence of protein biomarkers in the urine (Photo courtesy of the Washington University School of Medicine).

Urinary Proteins Kidney Cancer Biomarkers

Two urinary proteins are elevated in individuals with kidney cancer or papillary renal cell carcinoma, and are candidates to serve as biomarkers for early detection of the disease.  More...
29 Mar 2015
Image: Fine needle aspiration cytology of a thyroid nodule showing benign epithelial cells, colloid, and occasional macrophages, typical of a colloid nodule (Photo courtesy of Shahidul Islam, MD, PhD).

Benign Thyroid Nodules Follow-Up Shows Favorable Prognosis

A majority of asymptomatic, benign thyroid nodules exhibited no significant change in size, after five years of follow-up, or actually decreased in size, and diagnoses of thyroid cancer were rare.    More...
24 Mar 2015
Image: Histopathology of cerebral diffuse beta amyloid plaque (Photo courtesy of Dr. Dimitri P. Agamanolis, MD).

Blood-Based Test Developed for Diagnosing Alzheimer's Disease

A simple blood test has been developed to confirm the presence of beta amyloid proteins in the brain, which is a hallmark of Alzheimer's disease, and could be a key advance in diagnosing this neurodegenerative disorder.   More...
23 Mar 2015

British Genomic Study Finds Fifteen New Breast Cancer Loci

British genomic and cancer researchers have identified 15 previously unknown loci associated with the risk of developing breast cancer.  More...
22 Mar 2015
Image: The MiSeq desktop sequencer (Photo courtesy of Konrad Förstner).

Healthy-Looking Prostate Cells Mask Cancer-Causing Mutations

Genome-wide DNA sequencing has been used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of individuals.  More...
18 Mar 2015
Image: Manual Tissue Arrayer for the construction of tissue microarrays (Photo courtesy of Beecher Instruments Inc.).

Biomarkers Show Promise Improving Prostate Cancer Care

Two biomarkers have been discovered that may improve oncologists’ ability to predict which patients’ prostate cancer will recur after surgery, long before the development of visible cancer elsewhere in the body.  More...
18 Mar 2015
Image: Histopathology of esophageal carcinoma showing infiltrating nests of neoplastic cells (Photo courtesy of Dr. Elliot Weisenberg, MD).

Multianalyte Test Predicts Drug Resistance in Esophageal Cancer

A multianalyte algorithmic immunohistochemistry assay accurately identifies patients with locoregional esophageal adenocarcinoma who exhibit extreme resistance to neoadjuvant chemoradiotherapy.   More...
16 Mar 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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