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Pathology

Image: A micrograph of circulating tumor cells (CTCs) visualized by in situ RNA labeling (Photo courtesy of Wikimedia Commons).

Circulating Tumor Cells Provide Information Leading to Liquid Biopsy Biomarkers

Genomic analysis of pooled circulating tumor cells (CTCs) from men with metastatic castration-resistant prostate cancer revealed a reproducible, but highly complex pool of potential molecular biomarkers. More...
04 Oct 2016
Image: The C Scanner high-resolution microarray scanner (Photo courtesy of Agilent Technologies).

Method Developed Predicts Disease Activity in Multiple Sclerosis

Multiple sclerosis, or MS, is an inflammatory disease of the central nervous system that mainly affects young adults and it is not currently possible to know which individuals with multiple sclerosis, a life-long condition, risk developing severe disease. More...
28 Sep 2016
Image: The metabolic profiler system based on nuclear magnetic resonance (NMR) and mass spectrometry (MS) (Photo courtesy of Bruker BioSpin).

Protein Particle Parameters Help Differentiate Acute Kawasaki Disease

Kawasaki disease (KD) is a self-limited vasculitis that typically presents in young children as an acute illness with fever and mucocutaneous changes. If KD is incorrectly diagnosed or left untreated, coronary artery aneurysms (CAA) may develop, predisposing KD patients to long-term cardiovascular complications including myocardial ischemia and infarction. More...
28 Sep 2016
Image: A colorized scanning electron micrograph (SEM) of human prostate cancer cells (Photo courtesy of Dr. Gopal Murti).

Tumor Analysis Method Identifies High-Risk Prostate Cancer

A new way to identify which prostate cancer patients are likely to develop aggressive types of the disease, even if their tumors at first appear to be lower risk, has been created. More...
21 Sep 2016
Image: A colorized scanning electron micrograph (SEM) of esophageal cancer cells (Photo courtesy of the University of California-Davis).

New Test Could Revolutionize Cancer Diagnosis

A new blood test has been developed that could detect cancer earlier than ever before and it will change the way cancer is diagnosed, and in turn potentially save millions of lives. More...
21 Sep 2016
Image: The nCounter analysis system (Photo courtesy of NanoString Technologies).

Rare Inflammatory Disease Identified in Children

A rare, deadly inflammatory disease among young children, known as otulipenia has been discovered, and it is caused by the malfunction of OTULIN, a gene on chromosome 5 that regulates the development of new blood vessels and the mobilization of infection-fighting cells and proteins. More...
20 Sep 2016
Image: The NuQ Triage colorectal cancer screening test detects epigenetic changes to nucleosomes (DNA fragments) (Photo courtesy of VolitionRx).

Triage Colorectal Cancer Screening Test Should Reduce Colonoscopy Referral

The most frequently used first line screening test for colorectal cancer across Europe is the fecal immunochemical test (FIT) and patients with a positive score following FIT tests are then referred for colonoscopy. More...
20 Sep 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.