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Pathology

Image: Histopathology of an anaplastic astrocytoma showing marked nuclear pleomorphism. Note the atypical mitosis in the center (Photo courtesy of Dr. Peter C. Burger, MD).

Prognostic Marker Gene Found for Anaplastic Astrocytoma

A gene encoding for the enzyme isocitrate dehydrogenase 1 might be prognostic marker for a rare form of brain cancer known as anaplastic astrocytoma.  More...
23 Jun 2015
Image: Histopathology of classical Hodgkin lymphoma (Photo courtesy of Dr. John K.C. Chan).

Early-Stage Cancers May Be Detected with Noninvasive Prenatal Testing

A noninvasive prenatal testing is a screening technique used to detect Down syndrome and other conditions involving chromosomal abnormalities in a developing fetus.   More...
23 Jun 2015
Image: The Invitrogen Qubit Fluorometer for routine DNA, RNA, and protein quantitation (Photo courtesy of Life Technologies).

Endoscopic Samples Show Precancerous Genomic Changes in Barrett's Esophagus

Next-generation sequencing has been used to detect genomic mutations in precancerous esophageal tissue, which may improve cancer surveillance and early detection in patients with Barrett's esophagus.  More...
22 Jun 2015
Image: Micrograph of plasma cell with distinct clear perinuclear region of the cytoplasm containing a large number of Golgi bodies (Photo courtesy of Wikimedia Commons).

Circulating Biomarker for Autoimmune Disease Activity Identified

A circulating biomarker has been identified that shows potential for monitoring autoimmune diseases such as multiple sclerosis and lupus erythematosus.  More...
22 Jun 2015
Image: Highly magnified view of brain tumor (glioma) cells (Photo courtesy of the University of California, San Francisco).

Panel of Genetic Biomarkers Separates Brain Tumors into Five Distinct Classes

A panel of three genetic biomarkers has been identified that can differentiate brain tumors into five principal groups.  More...
21 Jun 2015
Image: Histopathology of a biopsy smear from a patient with squamous cell carcinoma in the anal canal showing proliferation of atypical cells that infiltrate the stromal (Photo courtesy of Muñiz Hospital).

Biomarker Analysis Reveals Treatment Targets in Anal Cancer

Squamous cell anal carcinoma is a rare, human papillomavirus-associated malignancy accounting for 2% of digestive system cancers and usually these malignancies are detected early and successfully managed with chemoradiation.  More...
16 Jun 2015
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Computer-Aided Microscopy Facilitates Autoimmune Disease Diagnostics

A new software and immunofluorescence microscope system that supports automated imaging and interpretation for clinical diagnostics now provides specialized software for autoimmune disease identification, including analysis of anti-nuclear antibodies and anti-neutrophil cytoplasm antibodies.   More...
15 Jun 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.