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Pathology

Image: The TMArrayer, a semi-automated tissue array device (Photo courtesy of Pathology Devices).

Prognostic Protein Biomarker Found for Esophageal Adenocarcinoma

Podocalyxin-like protein (PODXL) is a cell surface transmembrane glycoprotein, the expression of which has been associated with poor prognosis in a range of malignancies including glioblastoma multiforme, breast cancer, bladder cancer, periampullary and pancreatic adenocarcinoma and colorectal cancer. More...
31 Aug 2016
Image: A new study shows helical CT scans may reduce lung cancer mortality (Photo courtesy of MedicineWorld).

Study Highlights Importance of Regular Lung Cancer Screenings for Higher Risk Patients

Researchers have found that patients who tested negative for lung cancer (LC) in an LDCT (low-dose helical computed tomography) screening, but later went on to develop lung cancer within the following two years, had poorer outcomes than patients who initially had a non-cancerous positive screen test result. More...
29 Aug 2016
Image: A microscopic view of a colon cancer section (Photo courtesy of IDIBELL-Bellvitge Biomedical Research Institute).

Epigenetic Similarity in Cancer Cells Characterizes More Aggressive Tumors

Cancer researchers have found that the degree of epigenetic similarity among colorectal tumor cells was reflected in patients as significantly shortened relapse-free survival time and shortened time of overall survival. More...
29 Aug 2016
Image: The Rotor-Gene real-time PCR system (Photo courtesy of Qiagen).

Early Detection Identified for Leukemia Patients' Resistance to Therapy

A world-first breakthrough in the early detection of patients' resistance to a common treatment for chronic myeloid leukemia has been made. The discovery offers some hope that the patients' treatment could be changed sooner to improve their chances of survival. More...
25 Aug 2016
Image: Using Kinect motion-capture camera may improve evaluation of gait pathology in multiple sclerosis patients by increasing objectivity in diagnosis and treatment monitoring (Photo courtesy of the Montreal Neurological Institute & Hospital and McGill University).

Interactive Video Gaming Device Could Aid MS Patients

A commonly used 3D depth-sensing camera could become a low-cost means of monitoring treatment effectiveness for walking difficulties of patients with gait-impairing diseases such as multiple sclerosis (MS). More...
23 Aug 2016
Image: Different colored dots represent the status of micro RNA in the blood. Researchers looked for similarities among blood samples from Parkinson\'s patients (Photo courtesy of Van Andel Research Institute).

Parkinson's Disease Risk Indicators Found in Diverse Tissues

Tiny changes in DNA that have been linked to Parkinson's disease, the second most common neurodegenerative disorder after Alzheimer's, were found not only in brain cells, where they were expected, but also in liver, fat, immune and developmental cells. More...
18 Aug 2016
Image: A whole-mount section of the prostate from a cystoprostatectomy specimen with extension of the urothelial carcinoma of the bladder to the prostate (arrows). The encircled area is an incidental prostatic carcinoma (Photo courtesy of European Urology).

Biomarker of Aggressive Prostate Cancer Discovered

The level of a specific molecule present in prostate tumors is an indicator of whether the cancer is aggressive and likely to spread and this will aid future clinical tests to help doctors decide how best to treat prostate tumors. More...
18 Aug 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.